Atorvastatin calcium

Name: Atorvastatin calcium
SKU: A11800

目录号: A11800

HMG-CoA reductase 抑制剂

Atorvastatin calcium Chemical Structure

CAS NO. 134523-03-8

Atorvastatin calcium (Lipitor)是HMG-CoA还原酶的抑制剂，可用作降低胆固醇的药物，可阻止胆固醇的产生。

库存：现货

规格	价格	数量
50 mg	￥ 490.00
100 mg	￥ 840.00
250 mg	￥ 1,540.00
500 mg	￥ 2,660.00
10mM * 1mL in DMSO	￥ 525.00

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生物活性

Atorvastatin calcium (Lipitor)是HMG-CoA还原酶的抑制剂，可用作降低胆固醇的药物，可阻止胆固醇的产生。

靶点信息

HMG-CoA reductase (Cell-free assay)

溶解度 *

In vitro (25°C)	DMSO	92 mg/mL (79.63 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% DMSO+35% PEG300+2% Tween 80+ddH2O	3 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	8.66 mL	43.28 mL	86.55 mL
0.5 mM	1.73 mL	8.66 mL	17.31 mL
1 mM	0.87 mL	4.33 mL	8.66 mL
5 mM	0.17 mL	0.87 mL	1.73 mL

*The above data is based on the productmolecular weight 1155.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11800
作用机制	Inhibitor (抑制剂)
M. Wt	1155.34
Formula	2(C33H34FN2O5).Ca
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	134523-03-8
Synonyms	Lipitor
SMILES	CC(C)C1=C(C(=C(N1CC[C@H](C[C@H](CC(=O)[O-])O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4.CC(C)C1=C(C(=C(N1CC[C@H](C[C@H](CC(=O)[O-])O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4.[Ca+2]