Auglurant

目录号: A20958

mGlu5 antagonist

Auglurant

Auglurant Chemical Structure

CAS NO. 1396337-04-4

Auglurant (VU0424238) is a novel and selective mGlu5 antagonist with an IC50 value of 11 nM (rat) and an IC50 value of 14 nM (human). Auglurant (VU0424238) has an acceptable CNS penetration.

库存: 现货

规格 价格 数量
1 mg
¥ 2,240.00
5 mg
¥ 6,720.00
10 mg
¥ 11,200.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Auglurant (VU0424238) is a novel and selective mGlu5 antagonist with an IC50 value of 11 nM (rat) and an IC50 value of 14 nM (human). Auglurant (VU0424238) has an acceptable CNS penetration.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.74 mL 153.7 mL 307.41 mL
0.5 mM 6.15 mL 30.74 mL 61.48 mL
1 mM 3.07 mL 15.37 mL 30.74 mL
5 mM 0.61 mL 3.07 mL 6.15 mL

*The above data is based on the productmolecular weight 325.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A20958
作用机制 Antagonist (拮抗剂)
M. Wt 325.3
Formula C16H12FN5O2
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1396337-04-4
Synonyms VU0424238, VU 0424238, VU-0424238
SMILES CC1=NC(C(NC2=CC=C(F)C=N2)=O)=CC(OC3=CN=CN=C3)=C1

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