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AUT1 is a Kv3 potassium channel modulator with pEC50s of 5.33 and 5.31 for human recombinant Kv3.1b and Kv3.2a, respectively, exhibits 10-fold lower potency at human recombinant Kv3.3 channel (pEC50, 4.5).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 29.29 mL | 146.47 mL | 292.94 mL |
| 0.5 mM | 5.86 mL | 29.29 mL | 58.59 mL |
| 1 mM | 2.93 mL | 14.65 mL | 29.29 mL |
| 5 mM | 0.59 mL | 2.93 mL | 5.86 mL |
*The above data is based on the productmolecular weight 341.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A18648 |
|---|---|
| 作用机制 | Modulator (调节剂) |
| M. Wt | 341.37 |
| Formula | C18H19N3O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1311136-84-1 |
| Synonyms | AUT-1; AUT 1; AUT1 |
| SMILES | O=C1N(C2=CC=C(OC3=CC=C(C)C(OC)=C3)N=C2)C([C@@H](CC)N1)=O |
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