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AZ 23是一种有效的选择性酪氨酸激酶Trk抑制剂，对TrkA和TrkB的IC50分别为2和8 nM。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.52 mL | 127.61 mL | 255.21 mL |
| 0.5 mM | 5.1 mL | 25.52 mL | 51.04 mL |
| 1 mM | 2.55 mL | 12.76 mL | 25.52 mL |
| 5 mM | 0.51 mL | 2.55 mL | 5.1 mL |
*The above data is based on the productmolecular weight 391.83. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A12666 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 391.83 |
| Formula | C17H19ClFN7O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 915720-21-7 |
| Synonyms | AZ23, AZ-23 |
| SMILES | C[C@@H](C1=NC=C(C=C1)F)NC2=NC=C(C(=N2)NC3=CC(=NN3)OC(C)C)Cl |
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