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AZ32是ATM激酶的特异性抑制剂，对小鼠具有良好的BBB渗透性，ATM酶的IC50值<0.0062 uM。它对ATR有足够的选择性，并且具有较高的细胞通透性。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.45 mL | 152.27 mL | 304.53 mL |
| 0.5 mM | 6.09 mL | 30.45 mL | 60.91 mL |
| 1 mM | 3.05 mL | 15.23 mL | 30.45 mL |
| 5 mM | 0.61 mL | 3.05 mL | 6.09 mL |
*The above data is based on the productmolecular weight 328.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16814 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 328.37 |
| Formula | C20H16N4O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | Not Available N/A |
| Synonyms | AZ-32, AZ 32 |
| SMILES | O=C(NC)C(C=C1)=CC=C1C2=CN=C3C=NC(C4=CC=CC=C4)=CN32 |
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