Azacitidine(Vidaza)

Name: Azacitidine(Vidaza)
SKU: A10105

目录号: A10105

DNMT 抑制剂

Azacitidine(Vidaza) Chemical Structure

CAS NO. 320-67-2

Azacitidine (Vidaza)是DNA和RNA中使用的胞嘧啶核苷的化学类似物，主要用于治疗骨髓增生异常综合症（MDS）。

库存：现货

规格	价格	数量
100 mg	￥ 378.00
10mM * 1mL in DMSO	￥ 448.00

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生物活性

Azacitidine (Vidaza)是DNA和RNA中使用的胞嘧啶核苷的化学类似物，主要用于治疗骨髓增生异常综合症（MDS）。

靶点信息

DNA methyltransferase (Cell-free assay)

溶解度 *

In vitro (25°C)	DMSO	Warmed: 45 mg/mL (184.28 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5% DMSO+30% PEG 300+ddH2O	9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	40.95 mL	204.75 mL	409.5 mL
0.5 mM	8.19 mL	40.95 mL	81.9 mL
1 mM	4.1 mL	20.48 mL	40.95 mL
5 mM	0.82 mL	4.1 mL	8.19 mL

*The above data is based on the productmolecular weight 244.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10105
作用机制	Inhibitor (抑制剂)
M. Wt	244.2
Formula	C8H12N4O5
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	320-67-2
Synonyms	5-azacytidine, Mylosar, Ladakamycin, Vidaza
SMILES	C1=NC(=NC(=O)N1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)N