AZD3514

Name: AZD3514
SKU: A12396

目录号: A12396

AR 抑制剂 downregulator

AZD3514 Chemical Structure

CAS NO. 1240299-33-5

AZD3514是一种有效的雄激素受体下调剂，具有潜在的抗癌活性。

库存：现货

规格	价格	数量
5 mg	￥ 420.00
10 mg	￥ 700.00
25 mg	￥ 1,400.00
100 mg	￥ 4,200.00
10mM * 1mL in DMSO	￥ 1,071.00

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产品仅用于科学研究，不针对患者销售，望谅解.

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生物活性

AZD3514是一种有效的雄激素受体下调剂，具有潜在的抗癌活性。

靶点信息

Androgen Receptor
2.2 μM(Ki)

溶解度 *

In vitro	DMSO	97 mg/mL (186.7 mM)
	Water	Insoluble
	Ethanol	97 mg/mL (186.7 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.25 mL	96.24 mL	192.47 mL
0.5 mM	3.85 mL	19.25 mL	38.49 mL
1 mM	1.92 mL	9.62 mL	19.25 mL
5 mM	0.38 mL	1.92 mL	3.85 mL

*The above data is based on the productmolecular weight 519.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12396
作用机制	Inhibitor (抑制剂)
M. Wt	519.56
Formula	C25H32F3N7O2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1240299-33-5
Synonyms	AZD 3514, AZD-3514
SMILES	CC(=O)N1CCN(CC1)CCOC2=CC=C(C=C2)C3CCN(CC3)C4=NN5C(=NN=C5C(F)(F)F)CC4