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β-lactamase

β-lactamase

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Avibactam sodium

Catalog No. A17306
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non-β-lactam β-lactamase inhibitor

Avibactam sodium (NXL-104) is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively. 了解更多

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Zidebactam sodium salt

Catalog No. A21896
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β-lactamase inhibitor

Zidebactam sodium salt (WCK-5107 sodium salt) is a potent β-lactamase inhibitor. Zidebactam also is a penicillin-binding protein2 (PBP2) inhibitor with an IC50 of 0.26 μg/mL. 了解更多

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Nacubactam

Catalog No. A19471
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non-β-lactam-β-lactamase inhibitor

Nacubactam (OP0595 free acid) is a potent non-β-lactam-β-lactamase inhibitor with activity against class A and class C β-lactamases. 了解更多

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Taniborbactam

Catalog No. A20232
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β-lactamase inhibitor

Taniborbactam is a potent inhibitor of β-lactamase, with IC50s of <100 nM for SHV-5, KPC-2, VIM-2, and AmpC β-lactamase, and 0.1 to 1 μM for OXA-1 β-lactamase, used in the research of bacterial infections. 了解更多

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Vaborbactam

Catalog No. A20638
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β-lactamase inhibitor

Vaborbactam is a cyclic boronic acid pharmacophore β-lactamase inhibitor. 了解更多

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BRL-42715

Catalog No. A20726
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β-lactamase inhibitor

BRL-42715 is a potent inhibitor of a broad range of bacterial beta-lactamases (β-lactamase) . 了解更多

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Avibactam

Catalog No. A11299
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β-lactamase 抑制剂

Avibactam是一种共价，可逆的非β-内酰胺β-内酰胺酶抑制剂。了解更多

Product Citations (3)

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- Moonsuk Bae, .et al. In Vitro Activities of Ceftazidime-Avibactam and Aztreonam-Avibactam at Different Inoculum Sizes of Extended-Spectrum β-Lactam-Resistant Enterobacterales Blood Isolates, Antibiotics (Basel), 2021, Dec 5;10(12):1492 PMID: 34943704
- Taeeun Kim, .et al. In Vitro Activities and Inoculum Effects of Ceftazidime-Avibactam and Aztreonam-Avibactam against Carbapenem-Resistant Enterobacterales Isolates from South Korea, Antibiotics (Basel), 2020, Dec 15;9(12):912 PMID: 33334045
- Annelien Everaert, .et al. Effect of β-Lactamase inhibitors on in vitro activity of β-Lactam antibiotics against Burkholderia cepacia complex species, Antimicrob Resist Infect Control, 2016, 5: 44 PMID: 27895902
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Sulbactam

Catalog No. A11648
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β-lactamase 抑制剂

Sulbactam是一种β-内酰胺酶抑制剂，平均IC50为0.8μM。了解更多

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- Pholwat S, .et al. Genotypic antimicrobial resistance assays for use on E. coli isolates and stool specimens, PLoS One, 2019, May 10;14(5):e0216747 PMID: 31075137
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Clavulanic acid

Catalog No. A12384
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Clavulanic acid是一种基于机制的β-内酰胺酶，与青霉素类抗生素联合抑制，以克服某些类型的抗生素耐药性。了解更多

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AAI101

Catalog No. A18341
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β-lactamase 抑制剂

AAI-101, also known as Enmetazobactam, is a beta lactamase inhibitor potentially for the treatment of multi-drug resistant gram-negative bacterial infections. 了解更多

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Zidebactam

Catalog No. A18722
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β-lactamase 抑制剂

Zidebactam (WCK-5107) is a potent β-lactamase inhibitor. Zidebactam also is a penicillin-binding protein2 (PBP2) inhibitor with an IC50 of 0.26 μg/mL. 了解更多

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VNRX-5133

Catalog No. A18824
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β-lactamase 抑制剂

VNRX-5133 is a cyclic boronate β-lactamase inhibitor. 了解更多

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