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BI 224436是一种新型的HIV-1非催化位点整合酶抑制剂。具有针对不同HIV-1实验室菌株的<15 nM的抗病毒EC50,细胞毒性> 90μM。
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 22.6 mL | 112.99 mL | 225.98 mL |
0.5 mM | 4.52 mL | 22.6 mL | 45.2 mL |
1 mM | 2.26 mL | 11.3 mL | 22.6 mL |
5 mM | 0.45 mL | 2.26 mL | 4.52 mL |
*The above data is based on the productmolecular weight 442.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A16018 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 442.51 |
Formula | C27H26N2O4 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 1155419-89-8 |
Synonyms | BI224436, BI-224436 |
SMILES | CC1=NC2=CC=CC=C2C(=C1C(C(=O)O)OC(C)(C)C)C3=C4C5=C(C=C3)OCCC5=CC=N4 |
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