BMS303141

Name: BMS303141
SKU: A13807

目录号: A13807

ATP-citrate lyase 抑制剂

BMS303141 Chemical Structure

CAS NO. 943962-47-8

BMS303141是有效的ATP柠檬酸裂解酶（ACL）抑制剂。BMS303141以8μM的IC50抑制HepG2细胞中的脂质合成，并在鼠类高脂血症模型中降低血浆甘油三酸酯。

库存：现货

规格	价格	数量
10 mg	￥ 595.00
25 mg	￥ 1,120.00
50 mg	￥ 2,100.00
100 mg	￥ 3,360.00

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生物活性

BMS303141是有效的ATP柠檬酸裂解酶（ACL）抑制剂。BMS303141以8μM的IC50抑制HepG2细胞中的脂质合成，并在鼠类高脂血症模型中降低血浆甘油三酸酯。

溶解度 *

In vitro	DMSO	73 mg/mL (172.04 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.57 mL	117.84 mL	235.68 mL
0.5 mM	4.71 mL	23.57 mL	47.14 mL
1 mM	2.36 mL	11.78 mL	23.57 mL
5 mM	0.47 mL	2.36 mL	4.71 mL

*The above data is based on the productmolecular weight 424.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A13807
作用机制	Inhibitor (抑制剂)
M. Wt	424.3
Formula	C19H15Cl2NO4S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	943962-47-8
Synonyms	BMS 303141, BMS-303141
SMILES	COC1=C(C=C(C=C1)C2=CC=CC=C2)NS(=O)(=O)C3=CC(=CC(=C3O)Cl)Cl