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BNS-22是Topo II的有效小分子抑制剂（Topo II alpha和Topo II beta的IC50分别为2.8 M和0.42 M）。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.54 mL | 122.71 mL | 245.42 mL |
| 0.5 mM | 4.91 mL | 24.54 mL | 49.08 mL |
| 1 mM | 2.45 mL | 12.27 mL | 24.54 mL |
| 5 mM | 0.49 mL | 2.45 mL | 4.91 mL |
*The above data is based on the productmolecular weight 407.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13443 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 407.46 |
| Formula | C24H25NO5 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1151668-24-4 |
| Synonyms | BNS22, BNS 22, Topoisomerase II Inhibitor |
| SMILES | CCCC1=CC(=O)OC2=C1C(=CC(=C2C(=O)N3CCCC4=CC=CC=C43)OC)OC |
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