Bosentan Hydrate

目录号: A14944

ET-A and ET-B 拮抗剂

Bosentan Hydrate

Bosentan Hydrate Chemical Structure

CAS NO. 157212-55-0

Bosentan Hydrate是ET-A和ET-B的内皮素(ET)受体拮抗剂,Ki分别为4.7 nM和95 nM。

库存: 现货

规格 价格 数量
50 mg
¥ 420.00
100 mg
¥ 700.00
500 mg
¥ 2,100.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Bosentan Hydrate是ET-A和ET-B的内皮素(ET)受体拮抗剂,Ki分别为4.7 nM和95 nM。
In vitro (25°C) DMSO 92 mg/mL (161.51 mM)
Water Insoluble
Ethanol 2 mg/mL (3.51 mM)
In vivo 2% DMSO+30% PEG 300+2% Tween 80+ddH2O 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.56 mL 87.78 mL 175.55 mL
0.5 mM 3.51 mL 17.56 mL 35.11 mL
1 mM 1.76 mL 8.78 mL 17.56 mL
5 mM 0.35 mL 1.76 mL 3.51 mL

*The above data is based on the productmolecular weight 569.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14944
作用机制 Antagonist (拮抗剂)
M. Wt 569.63
Formula C27H29N5O6S.H2O
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 157212-55-0
Synonyms Ro 47-0203
SMILES CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)NC2=C(C(=NC(=N2)C3=NC=CC=N3)OCCO)OC4=CC=CC=C4OC.O

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