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BRD-IN-3 ((R,R)-36n) is a highly potent PCAF bromodomain (BRD) inhibitor, with an IC50 of 7 nM. BRD-IN-3 also exhibits activity against GCN5 and FALZ.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.29 mL | 126.44 mL | 252.88 mL |
| 0.5 mM | 5.06 mL | 25.29 mL | 50.58 mL |
| 1 mM | 2.53 mL | 12.64 mL | 25.29 mL |
| 5 mM | 0.51 mL | 2.53 mL | 5.06 mL |
*The above data is based on the productmolecular weight 395.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A18454 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 395.45 |
| Formula | C21H25N5O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 2351938-32-2 |
| SMILES | CN(C1)C[C@H](NC(N2C)=NC3=C(NC=C3)C2=O)C[C@@H]1C4=CC=C5OCCOC5=C4 |
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