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Calcium Channels

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  1. BAPTA/AM
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    BAPTA/AM

    Catalog No. A14023
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    Selective calcium chelator
    BAPTA/AM是一种细胞内钙螯合剂，可通过脂氧合酶介导的自由基在小鼠皮层培养物中诱导延迟性坏死。 了解更多
  2. Dantrolene
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    Dantrolene

    Catalog No. A13928
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    Ca2+ release 抑制剂
    Dantrolene是一种肌肉松弛剂，其作用可能是通过消除对ryanodine受体的作用来消除肌肉细胞中的兴奋-收缩偶联。 了解更多
  3. Atagabalin
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    Atagabalin

    Catalog No. A13402
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    Atagabalin与加巴喷丁相关，加巴喷丁同样与α结合。2β钙通道(1和2)。 了解更多
  4. Berbamine
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    Berbamine

    Catalog No. A14794
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    Calcium channel blocker
    Berbamine是钙通道阻滞剂。 了解更多
  5. (S)-Amlodipine
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    (S)-Amlodipine

    Catalog No. A14935
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    Calcium channel blocker
    (S)-Amlodipine是氨氯地平的(S)-对映体，具有活性的二氢吡啶钙通道阻滞剂主要存在于(-)-异构体中。 了解更多
  6. NNC 55-0396
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    NNC 55-0396

    Catalog No. A15188
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    Calcium channel blocker
    NNC 55-0396是Mibefradil衍生物，是一种高度选择性的T型钙通道阻滞剂；分别在INS-1细胞中抑制Cav3.1 T型通道和HVA电流的IC50值为6.8和> 100μM。 了解更多
  7. NP118809
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    NP118809

    Catalog No. A15192
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    N-type calcium channel blocker
    NP118809是有效的N型钙通道阻滞剂（IC50 = 0.11 uM）；对L型钙通道的选择性好。 了解更多
  8. NS6180
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    NS6180

    Catalog No. A12405
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    K(Ca) 3.1 channel blocker
    NS6180是一种新型有效的选择性KCa3.1通道抑制剂（IC50 = 9 nM），可防止T细胞活化和炎症反应。 了解更多
  9. Bay K 8644
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    Bay K 8644

    Catalog No. A15875
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    Calcium Channel Activator
    Bay K 8644是一种有效的L型Ca2+通道选择性激活剂，IC50为17.3 nM。 了解更多
  10. Mibefradil dihydrochloride
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    Mibefradil dihydrochloride

    Catalog No. A12482
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    Calcium channel blocker
    Mibefradil dihydrochloride是钙通道阻滞剂，对T型Ca2+通道具有中等选择性，对T型和L型通道的IC50值分别为2.7 uM和18.6 uM。 了解更多
  11. Dantrolene sodium Hemiheptahydrate
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    Dantrolene sodium Hemiheptahydrate

    Catalog No. A16146
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    Dantrolene sodium是一种骨骼肌松弛剂，其通过干扰肌肉纤维中的激发-收缩偶联起作用。 了解更多
  12. YM-58483
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    YM-58483

    Catalog No. A16346
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    CRAC channel 抑制剂
    YM-58483是CRAC通道和随后的Ca2+信号的第一个选择性抑制剂。 了解更多
  13. Chlorocresol
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    Chlorocresol

    Catalog No. A16444
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    Chlorocresol是ryanodine受体的活化剂。 了解更多
  14. Cinepazide maleate
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    Cinepazide maleate

    Catalog No. A16454
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    Cinepazide maleate是Cinepazide的马来酸盐形式，其为血管扩张剂。 了解更多
  15. Cinnarizine
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    Cinnarizine

    Catalog No. A16455
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    calcium channel blocker
    Cinnarizine是哌嗪的药物衍生物，其特征在于抗组胺药和钙通道阻滞剂。 了解更多
  16. Aranidipine
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    Aranidipine

    Catalog No. A18291
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    Calcium channel antagonist
    Aranidipine (MPC1304) is a Ca2+ channel antagonist with potent and long-lasting antihypertensive effects. 了解更多
  17. ABT-639
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    ABT-639

    Catalog No. A12330
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    T-type Ca2+ channel blocker
    ABT-639 is a novel, peripherally acting, selective T-type Ca2+ channel blocker. 了解更多
  18. Ca2+ channel agonist 1
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    Ca2+ channel agonist 1

    Catalog No. A12186
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    Ca2+ channel agonist/CDK2 inhibitor
    Ca2+ channel agonist 1 is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2, with EC50s of 14.23 μM and 3.34 μM, respectively, and is used as a potential treatment for motor nerve terminal dysfunction. 了解更多
  19. Barnidipine
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    Barnidipine

    Catalog No. A21940
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    L-type calcium antagonist
    Barnidipine (Mepirodipine) is an L-type calcium antagonist (CaA) with high affinity for [3H] initrendipine binding sites (Ki=0.21 nmol/l), has selective action against CaA receptors. 了解更多
  20. Dantrolene sodium
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    Dantrolene sodium

    Catalog No. A17644
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    Calcium channel proteins inhibitor
    Dantrolene sodium is a inhibitor of calcium channel proteins, inhibiting the release of Ca2+ from the sarcoplasm. Dantrolene sodium is a skeletal muscle relaxant which acts by blocking muscle contraction beyond the neuromuscular junction. 了解更多
  21. Tetrandrine (Fanchinine)
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    Tetrandrine (Fanchinine)

    Catalog No. A10921
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    Calcium Channel 抑制剂
    Tetrandrine (Fanchinine)是一种钙通道阻滞剂。粉防己碱具有抗炎和抗纤维化作用，使粉防己碱及其相关化合物潜在地用于治疗肺矽肺，肝硬化和类风湿性关节炎。 了解更多
  22. Astragaloside A
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    Astragaloside A

    Catalog No. A11405
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    Ca2+ signaling modulator
    Astragaloside A是缺氧条件下人脐静脉内皮细胞HIF-1α和通过PI3K/Akt途径血管生成的一种新型调节因子。 了解更多
  23. CK-1827452 (Omecamtiv mecarbil)
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    CK-1827452 (Omecamtiv mecarbil)

    Catalog No. A11206
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    Myosin activator
    CK-1827452 (Omecamtiv mecarbil)是选择性的心脏特异性肌球蛋白激活剂。 了解更多
  24. Manidipine 2HCl
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    Manidipine 2HCl

    Catalog No. A10554
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    Manidipine dihydrochloride是Manidipine的HCl盐形式，Manidipine是Ca2+电流的钙通道阻滞剂，IC50为2.6 nM。 了解更多
  25. Amlodipine
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    Amlodipine

    Catalog No. A10068
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    L-type calcium channel blocker
    Amlodipine是一种L型钙通道阻滞剂，具有降压作用。它抑制去极化大鼠主动脉中Ca2 +诱导的收缩（IC50 = 1.9 nM），并在心血管疾病中显示出血管保护作用。 了解更多
  26. Amlodipine besylate (Norvasc)
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    Amlodipine besylate (Norvasc)

    Catalog No. A10069
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    L-type calcium channel blocker
    Amlodipine besylate是一种L型钙通道阻滞剂，具有降压作用。它抑制去极化大鼠主动脉中Ca2 +诱导的收缩（IC50 = 1.9 nM）。 了解更多
  27. Cilnidipine
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    Cilnidipine

    Catalog No. A10215
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    Calcium channel blocker
    Cilnidipine是提供血管平滑肌中L型电压门控钙通道和交感神经末梢N型钙通道的双重阻滞剂。 了解更多
  28. Isradipine
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    Isradipine

    Catalog No. A10487
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    calcium channel blocker
    伊拉地平是二氢吡啶类钙通道阻滞剂。 了解更多
  29. Azelnidipine
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    Azelnidipine

    Catalog No. A11219
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    calcium channel blocker
    Azelnidipine是一种钙阻断剂，可减轻肝纤维化并可能增加抗氧化防御能力。可以减轻肝纤维化并可能增加抗氧化防御能力。 了解更多
  30. Lacidipine
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    Lacidipine

    Catalog No. A11729
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    Lacidipine是一种钙通道阻滞剂。 了解更多
  31. BAPTA tetrapotassium
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    BAPTA tetrapotassium

    Catalog No. A13989
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    Selective calcium chelator
    BAPTA tetrapotassium是一种选择性钙螯合剂，对Ca2+的亲和力大于Mg2+。 了解更多
  32. Nimodipine
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    Nimodipine

    Catalog No. A10645
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    Calcium Channel 抑制剂
    Nimodipine是一种L型Ca2+通道阻滞剂。 了解更多
  33. Nifedipine
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    Nifedipine

    Catalog No. A10643
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    L-type calcium channel blocker.
    Nifedipine是一种L型钙通道阻滞剂。 了解更多
  34. Pinaverium Bromide
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    Pinaverium Bromide

    Catalog No. A12684
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    Pinaverium Bromide是一种痉挛剂，抗胆碱能作用的发生率低。吡那溴铵也是解痉药。 了解更多
  35. Manidipine (Manyper)
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    Manidipine (Manyper)

    Catalog No. A10553
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    Manidipine (Manyper)是二氢吡啶化合物和钙通道蛋白抑制剂和拮抗剂。 了解更多
  36. Diltiazem HCl
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    Diltiazem HCl

    Catalog No. A10311
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    Diltiazem HCl是一种非二氢吡啶（非DHP）药物，称为钙通道阻滞剂，用于治疗高血压，心绞痛和某些类型的心律不齐。 了解更多
  37. Diethylstilbestrol
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    Diethylstilbestrol

    Catalog No. A10309
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    Diethylstilbestrol是一种合成的非甾体雌激素，于1938年首次合成。它也被分类为内分泌干扰物。 了解更多
  38. Clevidipine
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    Clevidipine

    Catalog No. A11746
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    Calcium channel blocker
    Clevidipine是一种二氢吡啶类钙通道阻滞剂，用于在口服治疗不可行或不理想时降低血压。 了解更多
  39. Nilvadipine (ARC029)
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    Nilvadipine (ARC029)

    Catalog No. A11731
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    calcium channel blocker
    Nilvadipine (ARC029)是一种钙通道阻滞剂（CCB），用于治疗高血压和慢性主要脑动脉阻塞。 了解更多
  40. Benidipine hydrochloride
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    Benidipine hydrochloride

    Catalog No. A11730
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    Benidipine hydrochloride是一种长效的T型钙通道阻滞剂，对高血压糖尿病患者的血压和肾功能有影响。 了解更多
  41. Caldaret
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    Caldaret

    Catalog No. A13148
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    intracellular Ca2+ handling modulator
    Caldaret is an intracellular Ca2+ handling modulator that acts through reverse mode Na+/Ca2+ exchanger inhibition. 了解更多
  42. ABT-639 hydrochloride
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    ABT-639 hydrochloride

    Catalog No. A12571
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    T-type Ca2+ channel blocker
    ABT-639 hydrochloride is a novel, peripherally acting, selective T-type Ca2+ channel blocker. 了解更多
  43. (S)-(-)-Bay-K-8644
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    (S)-(-)-Bay-K-8644

    Catalog No. A21164
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    L-type Ca2+ channel agonist
    (S)-(-)-Bay-K-8644 is an agonist of L-type Ca2+ channel. (S)-(-)-Bay-K-8644 activates Ba2+ currents (IBa) (EC50=32 nM). 了解更多
  44. TTA-Q6
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    TTA-Q6

    Catalog No. A21360
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    T-type Ca2+ channel antagonist
    TTA-Q6 is a selective T-type Ca2+ channel antagonist, used in the neurological disease. 了解更多
  45. TTA-Q6(isomer)
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    TTA-Q6(isomer)

    Catalog No. A21724
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    T-type Ca2+ channel antagonist
    TTA-Q6(isomer) is an isomer of TTA-Q6. TTA-Q6 is a selective T-type Ca2+ channel antagonist. 了解更多
  46. JTV-519 free base
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    JTV-519 free base

    Catalog No. A21846
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    Ca2+-dependent blocker
    TV-519 free base (K201 free base) is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle. Antiarrhythmic and cardioprotective properties. 了解更多
  47. GV-58
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    GV-58

    Catalog No. A21966
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    N- and P/Q-type Ca2+ channels agonist
    GV-58 is a potent, selective N- and P/Q-type Ca2+ channels agonist with EC50 of 7.21/8.81 uM for N-type/P-Q-type Ca2+ channel; 20-fold less potent CDK inhibitor activity. 了解更多

47 个项目

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  1. Inhibitor (抑制剂) (6)
  2. Agonist (激动剂) (3)
  3. Antagonist (拮抗剂) (4)
  4. Activator (激活剂) (2)
  5. Modulator (调节剂) (2)
  6. Blocker (阻断剂) (18)
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