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Candesartan (Atacand)是一种血管紧张素受体阻滞剂(也称为血管紧张素II受体拮抗剂或AIIRA)。
靶点信息
AT1 receptor | ||||
0.26 nM |
In vitro (25°C) | DMSO | 79 mg/mL (179.36 mM) | |
Water | Insoluble | ||
Ethanol | 1 mg/mL (2.27 mM) | ||
In vivo | 2% DMSO+40% PEG 300+2% Tween 80+ddH2O | 9 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 22.7 mL | 113.51 mL | 227.01 mL |
0.5 mM | 4.54 mL | 22.7 mL | 45.4 mL |
1 mM | 2.27 mL | 11.35 mL | 22.7 mL |
5 mM | 0.45 mL | 2.27 mL | 4.54 mL |
*The above data is based on the productmolecular weight 440.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A10175 |
---|---|
作用机制 | Antagonist (拮抗剂) |
M. Wt | 440.5 |
Formula | C24H20N6O3 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 139481-59-7 |
Synonyms | Blopress, Atacand, Amias, Ratacand |
SMILES | CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5)C(=O)O |
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