“bibx 1382”的搜索结果

25 个项目

每页

设置降序顺序
  1. BIBX 1382

    Catalog No. A11334
    Quick View
    EGFR 抑制剂
    BIBX 1382是一种细胞可渗透的嘧啶嘧啶化合物,可作为一种有效的,可逆的,ATP竞争性高选择性的EGFR抑制剂。 了解更多
  2. STING agonist-3

    Catalog No. A19882
    Quick View
    STING agonist
    STING agonist-3, compound 3, is a selective and non-nucleotide small-molecule STING agonist, which has durable anti-tumor effect and tremendous potential to improve treatment of cancer. 了解更多
  3. Estrone-N-O-C1-amido

    Catalog No. A19746
    Quick View
    estrogen ligand
    Estrone-N-O-C1-amido (ERα ligand 1) is an Estrone-based estrogen ligand, which targets estrogen receptor α (ERα). Estrone-N-O-C1-amido (ERα ligand 1) binds to cIAP1 ligand Bestatin via a linker to form SNIPER. 了解更多
  4. Mirogabalin besylate

    Catalog No. A19379
    Quick View
    ligand for the α2δ subunit of voltage-gated calcium channels
    Mirogabalin besylate is a selective and orally available ligand for the α2δ subunit of voltage-gated calcium channels, with Kds of 13.5 nM, 22.7 nM, 27 nM, and 47.6 nM for human α2δ-1, human α2δ-2, rat α2δ-1, and rat α2δ-2, respectively. 了解更多
  5. AN-3485

    Catalog No. A20989
    Quick View
    TLR inhibitor
    AN-3485 is a benzoxaborole analog, Toll-Like Receptor(TLR) inhibitor with IC50 values ranging from 18 to 580 nM. 了解更多
  6. diABZI STING agonist-1 trihydrochloride

    Catalog No. A21694
    Quick View
    STING receptor agonist
    diABZI STING agonist-1 (trihydrochloride) is a selective stimulator of interferon genes (STING) receptor agonist, with an EC50s of 130 for human PBMCs. 了解更多
  7. diABZI STING agonist-1

    Catalog No. A21688
    Quick View
    STING receptor agonist
    diABZI STING agonist-1 is a selective stimulator of interferon genes (STING) receptor agonist, with an EC50s of 130 nM for human PBMCs. 了解更多
  8. Mirogabalin

    Catalog No. A21626
    Quick View
    Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium channel complexes in the CNS. 了解更多
  9. Ipragliflozin L-Proline

    Catalog No. A21579
    Quick View
    SGLT2 inhibitor
    Ipragliflozin (L-Proline) is a highly potent and selective SGLT2 inhibitor with an IC50 of 2.8 nM; little and NO potency for SGLT1/3/4/5/6. 了解更多
  10. PF-00446687

    Catalog No. A21382
    Quick View
    MC4R agonist
    PF-00446687 is a potent, selective melanocortin-4 receptor (MC4R) agonist with EC50 of 12????1 nM. Pf-446687 is brain penetrant. 了解更多
  11. Pentiapine

    Catalog No. A12512
    Quick View
    dopamine release inhibitor
    Pentiapine is a novel dopamine release inhibitor. 了解更多
  12. Dipraglurant

    Catalog No. A11382
    Quick View
    mGluR5 antagonists
    Dipraglurant (ADX 48621) is a mGluR5 antagonists with IC50 of 0.021 μM. 了解更多
  13. MK-8719

    Catalog No. A18839
    Quick View
    OGA inhibitor
    MK-8719 is a highly potent and selective OGA inhibitor (EC50 = 52.7 nM) which is a Potential Treatment for Tauopathies. MK-8719 showed excellent CNS penetration that has been advanced to first-in-human phase I clinical trials. 了解更多
  14. AUH Human

    Catalog No. AP4083
    Quick View
    AU RNA Binding Protein/Enoyl-CoA Hydratase Human Recombinant 了解更多
  15. PAX8 Human

    Catalog No. AP1382
    Quick View
    Paired Box 8 Human Recombinant 了解更多
  16. Photochlor

    Catalog No. A13824
    Quick View
    Photochlor是一种亲脂性的第二代基于二氢卟酚的光敏剂。静脉内给药时,HPPH选择性地积聚在癌症或癌前细胞的细胞质中。 了解更多
  17. 21-Deacetoxy Deflazacort

    Catalog No. A13823
    Quick View
    21-Deacetoxy Deflazacort是Deflazacort(一种系统性的皮质类固醇)的中间体。 了解更多
  18. SC75741

    Catalog No. A14278
    Quick View
    NF-κB 抑制剂
    SC75741是有效的NF-kB抑制剂,EC50为200 nM。 了解更多
  19. TG 100572

    Catalog No. A13820
    Quick View
    VEGFR2/Src 抑制剂
    TG 100572是VEGFR2和Src激酶抑制剂。 了解更多
  20. Erastin

    Catalog No. A13822
    Quick View
    VDAC 抑制剂
    Erastin是一种细胞可渗透的哌嗪基-喹唑啉酮化合物,在具有H-Ras突变的细胞中表现出癌基因选择性致死性。 了解更多
  21. CGP77675

    Catalog No. A13821
    Quick View
    Src 抑制剂
    CGP77675是有效的Src激酶抑制剂。CGP77675抑制了肽底物的磷酸化和纯化Src的自磷酸化(分别为IC50:5-20和40 nM)。 了解更多
  22. APY29

    Catalog No. A13828
    Quick View
    IRE1α 抑制剂
    APY29抑制IRE1α自磷酸化(IC50 = 280 nM),并激活IRE1αRNase活性。 了解更多
  23. CK-636

    Catalog No. A13827
    Quick View
    Arp2/3 抑制剂
    CK-636是一种Arp2/3复合抑制剂。CK-636在Arp2和Arp3之间结合,似乎阻止了Arp2和Arp3进入其活性构象。 了解更多
  24. PTC-209

    Catalog No. A13826
    Quick View
    BMI-1 抑制剂
    PTC-209是一种新型的有效选择性BMI-1抑制剂,靶向BMI-1自我更新机制,IC50为?0.5μM。 了解更多
  25. Icotinib

    Catalog No. A13825
    Quick View
    EGFR 抑制剂
    Icotinib是一种有效的特异性EGFR抑制剂,IC50为5 nM,包括EGFR,EGFR(L858R),EGFR(L861Q),EGFR(T790M)和EGFR(T790M,L858R)。 了解更多

25 个项目

每页

设置降序顺序
Rewards