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Kv3 modulator 3
Catalog No. A18958 Kv3.1/Kv3.2/Kv3.3 channels modulatorKv3 modulator 3 (Compound 4) is a selective modulator of Kv3.1 and/or Kv3.2 and/or Kv3.3 channels extracted from patent WO2017098254A1, compound 4, has analgesic activity for use in the prophylaxis o or treatment of pain. 了解更多 -
Kv3 modulator 2
Catalog No. A18965 Kv3 channels modulatorKv3 modulator 2 (formula (I)) is a potent Kv3 channels modulator extracted from patent WO2018109484A1, compound formula (I) , has analgesic activity and is used in the prophylaxis or treatment of related disorders. 了解更多 -
Ulipristal acetate
Catalog No. A21041 progesterone receptor modulatorUlipristal (acetate) is a novel selective progesterone receptor modulator (SPRM) for the treatment of benign gynecological conditions such as uterine myoma. 了解更多 -
(Rac)-VU 6008667
Catalog No. A21939 mAChR M5 negative allosteric modulator(Rac)-VU 6008667 is a selective negative allosteric modulator of muscarinic acetylcholine receptor subtype 5 (M5 NAM) (IC50=1.8 μM, pIC50= 5.75), has high CNS penetration. 了解更多 -
(R)-ADX-47273
Catalog No. A21887 mGluR5 positive allosteric modulator(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator, with an EC50 of 168 nM for potentiation . 了解更多 -
PF-4778574
Catalog No. A21157 AMPA receptor positive allosteric modulatorPF-4778574 is a potent AMPA receptor positive allosteric modulator (PAM) that has been shown to enhance cognition in animal models. 了解更多 -
GLP-26
Catalog No. A18914 HBV capsid assembly modulatorGLP-26 is a HBV capsid assembly modulators (CAM), inhibits HBV DNA replication in Hep AD38 system (IC50=3 nM), and reduces cccDNA by >90% at 1 μM. GLP-26 disrupts the encapsidation of pre-genomic RNA, causes nucleocapsid disassembly and reduces cccDNA pools. 了解更多 -
PZ-2891
Catalog No. A18880 PANK modulatorPZ-2891 is an orally bioavailable, brain penetrant pantothenate kinase (PANK) modulator. PZ-2891 act as an orthosteric inhibitor at high concentrations and an allosteric activator at lower sub-saturating concentrations. PZ-2891 inhibits human pantothenate kinases PANK1β, PANK2, and PANK3 with IC50s of 40.2 nM, 0.7 nM and 1.3 nM, respectively. 了解更多 -
Lasofoxifene Tartrate
Catalog No. A18097 selective Estrogen receptor modulatorLasofoxifene tartrate is a third-generation selective estrogen receptor modulator. 了解更多 -
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KL1333
Catalog No. A17234 NAD+ ModulatorKL1333 is an orally available, small organic molecule that reacts with NAD(P)H:quinone oxidoreductase 1 (NQO1) as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation. KL-1333 Improves Energy Metabolism and Mitochondrial Dysfunction in MELAS Fibroblasts. 了解更多 -
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Tonabersat (SB-220453)
Catalog No. A11593
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