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19 个项目
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Serlopitant
Catalog No. A21582 Neurokinin-1 (NK-1) receptor antagonistSerlopitant is a selective Neurokinin-1 (NK-1) receptor antagonist. 了解更多 -
Vofopitant dihydrochloride
Catalog No. A21543 NK1 receptor antagonistVofopitant dihydrochloride (GR 205171A) is a potent, selective and orally available tachykinin neurokinin 1(NK1) receptor antagonist. 了解更多 -
Maropitant
Catalog No. A21473 -
Pavinetant
Catalog No. A21174 NK3R antagonistPavinetant (MLE-4901) is a neurokinin-3 receptor (NK3R) antagonist. 了解更多 -
Befetupitant
Catalog No. A13149 NK1R antagonistBefetupitant is a high-affinity, nonpeptide, competitive tachykinin 1 receptor (NK1R) antagonist. 了解更多 -
Tradipitant
Catalog No. A16918 -
Talnetant hydrochloride
Catalog No. A15255 NK3 receptor 拮抗剂Talnetant Hydrochloride是一种有效且选择性的NK3受体拮抗剂（ki = 1.4 nM，hNK-3-CHO）；对hNK-3受体的选择性是对hNK-2受体的100倍，在浓度高达100 uM时对hNK-1没有亲和力。 了解更多 -
Netupitant
Catalog No. A14428 NK1 receptor 拮抗剂Netupitant是一种选择性的神经激肽1（NK1）受体拮抗剂。它竞争性地结合并阻断中枢神经系统（CNS）中人类物质P/NK1受体的活性，从而抑制内源性速激肽神经肽物质P（SP）的NK1受体结合，这可能导致预防化疗引起的恶心和呕吐（CINV）。 了解更多 -
Rolapitant
Catalog No. A13680 NK1 receptor 拮抗剂Rolapitant，也称为SCH-619734，是一种选择性的，可生物利用的CNS渗透性神经激肽NK1受体拮抗剂，在呕吐动物模型中显示出行为效应。 了解更多 -
Fosaprepitant dimeglumine
Catalog No. A11069 -
Ibodutant (MEN 15596)
Catalog No. A13104 tachykinin NK2 receptor 拮抗剂Ibodutant (MEN 15596)是速激肽NK2受体拮抗剂，pKi 值为10.1，用于治疗腹泻型肠易激综合症（IBS-D）。 了解更多 -
GW679769 (Casopitant)
Catalog No. A13103 -
Vofopitant (GR 205171)
Catalog No. A12793 -
MK-0517 (Fosaprepitant)
Catalog No. A11756 neurokinin-1 receptor 拮抗剂MK-0517 (Fosaprepitant,L-758,298)是Aprepitant的水溶性磷酰基前药，它是NK1拮抗剂。 了解更多 -
Aprepitant (MK-0869)
Catalog No. A10083 neurokinin-1 receptor 拮抗剂Aprepitant (MK-0869)被归类为NK1拮抗剂。已经显示，阿瑞匹坦通过阻止P物质降落在大脑神经元受体上，从而抑制细胞毒性化疗药物引起的急性呕吐和延迟呕吐。还显示出它能增加5-HT3受体拮抗剂恩丹西酮和皮质类固醇地塞米松的活性，它们也可用于预防化学疗法引起的恶心和呕吐。 了解更多
19 个项目
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