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GW3965 HCl

Catalog No. A11204
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LXR-like receptors 激动剂

GW3965 HCl是一种选择性的口服活性肝X受体（LXR）完全激动剂。了解更多

Product Citations (3)

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- Mohácsik P, .et al. A Transgenic Mouse Model for Detection of Tissue-Specific Thyroid Hormone Action, Endocrinology, 2018, Feb 1;159(2):1159-1171 PMID: 29253128
- Pencheva N, .et al. Broad-spectrum therapeutic suppression of metastatic melanoma through nuclear hormone receptor activation., Cell., 2014, 156(5):986-1001 PMID: 24581497
- Bin Dong, .et al. High-fructose diet downregulates long-chain acyl-CoA synthetase 3 expression in liver of hamsters via impairing LXR/RXR signaling pathway, J Lipid Res., 2013, May; 54(5): 1241-1254. PMID: 23427282
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RGX-104 free Acid

Catalog No. A21513
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LXR agonist

RGX-104 free Acid is an orally bioavailable and potent liver-X nuclear hormone receptor (LXR) agonist that modulates innate immunity via transcriptional activation of the ApoE gene. 了解更多

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GW3965

Catalog No. A15100
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Liver X Receptor 激动剂

GW3965是hLXRα和hLXRβ的有效选择性LXR激动剂，EC50分别为190和30 nM。了解更多

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- B Dong ,etc. High-fructose diet downregulates long-chain acyl-CoA synthetase 3 expression in liver of hamsters via impairing LXR/RXR signaling pathway. Journal of lipid research, 2013, 54(5), 1241-1254.
- N Pencheva ,etc. Broad-spectrum therapeutic suppression of metastatic melanoma through nuclear hormone receptor activation. Cell, 2014, 156(5), 986-1001.