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搜索结果：“glucagon receptor”

“glucagon receptor”的搜索结果

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GW3965 HCl

Catalog No. A11204
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LXR-like receptors 激动剂

GW3965 HCl是一种选择性的口服活性肝X受体（LXR）完全激动剂。了解更多

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- Mohácsik P, .et al. A Transgenic Mouse Model for Detection of Tissue-Specific Thyroid Hormone Action, Endocrinology, 2018, Feb 1;159(2):1159-1171 PMID: 29253128
- Pencheva N, .et al. Broad-spectrum therapeutic suppression of metastatic melanoma through nuclear hormone receptor activation., Cell., 2014, 156(5):986-1001 PMID: 24581497
- Bin Dong, .et al. High-fructose diet downregulates long-chain acyl-CoA synthetase 3 expression in liver of hamsters via impairing LXR/RXR signaling pathway, J Lipid Res., 2013, May; 54(5): 1241-1254. PMID: 23427282
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NMDA

Catalog No. A12751
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NMDA receptor 激动剂

NMDA是一种原型NMDA受体激动剂。了解更多

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Eletriptan hydrobromide

Catalog No. A11418
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5-HT1B/1D receptor 激动剂

Eletriptan hydrobromide是一种选择性SR-1B/SR-1D激动剂。了解更多

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- Li Li, .et al. Delineating a serotonin 1B receptor circuit for appetite suppression in mice, J Exp Med, 2022, Aug 1;219(8):e20212307 PMID: 35796804
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Carvedilol

Catalog No. A11843
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β2-adrenergic receptor

Carvedilol是具有抗氧化特性的β1和β2肾上腺素能受体（AR）激动剂。了解更多

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Prednisone (Adasone)

Catalog No. A10752
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Glucocorticoid Receptor 激动剂

Prednisone (Adasone)可降低粘膜TNF-a的产生，肠道通透性和NF-kB表达水平。了解更多

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Aripiprazole (Abilify)

Catalog No. A11801
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5-HT1A receptor 激动剂

Aripiprazole (Abilify)是人5-HT1A受体部分激动剂，Ki为4.2 nM。了解更多

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- Jaime Osuna-Luque, .et al. Behavioral Mechanisms That Depend on Dopamine and Serotonin in Caenorhabditis elegans Interact With the Antipsychotics Risperidone and Aripiprazole, J Exp Neurosci, 2018, 12: 1179069518798628 PMID: 30245571
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Almotriptan malate (Axert)

Catalog No. A11799
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5-HT Receptor 激动剂

Almotriptan malate (Axert)是一种选择性的5-羟色胺1B/1D（5-HT1B/1D）受体激动剂，用于治疗成人偏头痛。了解更多

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- Li Li, .et al. Delineating a serotonin 1B receptor circuit for appetite suppression in mice, J Exp Med, 2022, Aug 1;219(8):e20212307 PMID: 35796804
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GW842166X

Catalog No. A11253
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CB2 receptor 激动剂

GW842166X是一种选择性的非大麻类CB2受体激动剂，EC50为63 nM，对CB1受体没有显著的活性。了解更多

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Clomipramine HCl

Catalog No. A10231
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5-HT Receptor 激动剂

Clomipramine HCl是下列转运蛋白的阻滞剂：5-羟色胺转运蛋白 (SERT)(Ki = 0.14 nM)，去甲肾上腺素转运蛋白（NET）(Ki = 54 nM)，多巴胺转运蛋白（DAT）(Ki = 3，020 nM)，甘氨酸转运蛋白（GlyT/LeuT）。了解更多

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Bethanechol chloride

Catalog No. A10180
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Muscarinic receptor 激动剂

Bethanechol chloride是拟副交感神经的胆碱氨基甲酸酯，可选择性刺激毒蕈碱受体，而不会对烟碱样受体产生任何影响。了解更多

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CGS 21680 HCl Hydrate

Catalog No. A11619
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Adenosine A2A Receptor 激动剂

CGS 21680 HCl是一种特定的腺苷A2A亚型受体激动剂。了解更多

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- Qian Wang, .et al. cAMP-producing chemogenetic and adenosine A2a receptor activation inhibits the inwardly rectifying potassium current in striatal projection neurons, Neuropharmacology, 2019, 148: 229-243 PMID: 30659840
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Detomidine hydrochloride

Catalog No. A10298
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Adrenergic Receptor 激动剂

Detomidine hydrochloride是具有镇痛作用的镇静剂。α2-肾上腺素能激动剂产生剂量依赖性的镇静和镇痛作用，并通过激活α2儿茶酚胺受体介导，从而引起负反馈反应，从而减少兴奋性神经递质的产生。了解更多

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Prucalopride

Catalog No. A11771
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5-HT Receptor 激动剂

Prucalopride是一种选择性的，高亲和力的5-HT4受体激动剂，作用于5-HT4A和5-HT4B受体，Ki分别为2.5 nM和8 nM，比作用于5-HT受体亚型选择性高290倍以上。了解更多

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- Pierre Meschin, .et al. p11 modulates calcium handling through 5-HT4R pathway in rat ventricular cardiomyocytes., Cell Calcium, 2015, Dec;58(6):549-57 PMID: 26427584
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Pramipexole dihydrochloride monohyrate

Catalog No. A10747
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Dopamine Receptor 激动剂

Pramipexole dihydrochloride monohyrate是非麦角灵类的多巴胺激动剂，适用于治疗早期帕金森氏病（PD）和不安腿综合征（RLS）。了解更多

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Phenylephrine HCl

Catalog No. A11666
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α1-adrenergic receptor 激动剂

Phenylephrine HCl是一种选择性的α1肾上腺素能受体激动剂，主要用作减充血剂，扩张瞳孔和增加血压的药物。了解更多

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Betamethasone dipropionate

Catalog No. A10130
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Glucocorticoid Receptor 激动剂

Betamethasone Dipropionate是糖皮质激素类固醇，具有抗炎和免疫抑制特性。了解更多

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Ramelteon (TAK-375)

Catalog No. A10777
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MT1/MT2-Receptor 激动剂

Ramelteon (TAK-375)是melatonin受体激动剂，对褪黑激素MT1（IC50 = 28.5±8.55 pM）和MT2（20.1±9.25 pM）受体均具有高亲和力，并且相对于MT3受体具有选择性。了解更多

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ADL5859 HCl

Catalog No. A11072
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Opioid Receptor 激动剂

ADL5859 HCl是高效的选择性δ阿片受体激动剂，Ki值为0.84 nM，ED50值为20 nM。了解更多

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Andarine (GTX-007)

Catalog No. A10076
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Androgen Receptor 激动剂

Andarine (GTX-007)是研究性的选择性雄激素受体调节剂（SARM）。了解更多

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Hexestrol

Catalog No. A10451
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Estrogen/progestogen Receptor 激动剂

Hexestrol是一种致癌的合成雌激素，可抑制微管聚合和带状结构的形成。它是脂质过氧化的抑制剂。了解更多

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Tianeptine sodium

Catalog No. A10931
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5-HT Receptor 激动剂

Tianeptine钠是体内和体外的选择性5-羟色胺再摄取促进剂（SSRE）。了解更多

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Mosapride citrate

Catalog No. A10607
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5-HT4-receptor 激动剂

Mosapride citrate起5-HT4受体激动剂和5-HT3受体拮抗剂的作用。了解更多

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