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搜索结果：“MK 1775”

“MK 1775”的搜索结果

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Sitagliptin

Catalog No. A14377
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DDP-4 抑制剂

Sitagliptin是二肽基肽酶-4（DPP-4）抑制剂类别降糖药（抗糖尿病药）。了解更多

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- Hae Jin Kim, .et al. Potentiation of endothelium-dependent vasorelaxation of mesenteric arteries from spontaneously hypertensive rats by gemigliptin, a dipeptidyl peptidase-4 inhibitor class of anti-diabetic drug, Korean J Physiol Pharmacol, 2018, Nov; 22(6): 713-719 PMID: 30402032
- Chintan N. Koyani, .et al. Saxagliptin but Not Sitagliptin Inhibits CaMKII and PKC via DPP9 Inhibition in Cardiomyocytes, Front Physiol, 2018, 9: 1622 PMID: 30487758
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MK-3102

Catalog No. A13310
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DPP-4 抑制剂

Omarigliptin (MK-3102)是一种竞争性的、可逆的DPP-4抑制剂(IC50 = 1.6 nM, Ki = 0.8 nM)。在所有检测的蛋白酶中，包括QPP, FAP, PEP, DPP8和DPP9等，对DPP-4具有高选择性，具有微弱的离子通道活性（IC50 > 30 μM at IKr, Caγ1.2, and Naγ1.5）。了解更多

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Sitagliptin phosphate monohydrate

Catalog No. A10848
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DDP-4 抑制剂

Sitagliptin phosphate monohydrate是二肽基肽酶-4（DPP-4）类的抗糖尿病（抗高血糖）药物。 DPP-4酶的抑制作用被认为会增加胰高血糖素样肽1（GLP-1），从而抑制胰高血糖素释放，刺激胰岛素释放并降低血糖。了解更多

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