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RI-2

Catalog No. A20992
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RAD51 inhibitor

RI-2 is a reversible RAD51 inhibitor, with an IC50 of 44.17 μM, and specifically inhibits homologous recombination repair in human cells. 了解更多

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CDKI-73

Catalog No. A21467
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CDK9 inhibitor

CDKI-73 is a potent CDK9 inhibitor with Ki of 4 nM; shows selective toxicity to CLL cells(LD50=80 nM) versus normal B cell and normal CD34+ cell(LD50>20 uM). 了解更多

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T56-LIMKi

Catalog No. A12266
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LIMK2 inhibitor

T56-LIMKi is a selective inhibitor of LIMK2; inhibits the growth of Panc-1 cells with an IC50 of 35.2 μM. 了解更多

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AAPK-25

Catalog No. A19085
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Aurora/PLK dual 抑制剂

AAPK-25 is a potent and selective Aurora/PLK dual inhibitor with anti-tumor activity, which can cause mitotic delay and arrest cells in a prometaphase, reflecting by the biomarker histone H3Ser10 phosphorylation and followed by a surge in apoptosis. 了解更多

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Ras-IN-3144

Catalog No. A17222
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pan-RAS inhibitor

Ras-IN-3144 is a pan-RAS inhibitor which inhibits RAS signaling pathways in cancer cells and prevents the growth of RAS mutant mouse cancer xenografts. 了解更多

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MRTX1257

Catalog No. A17223
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KRAS-G12C inhibitor

MRTX1257 is a potent, selective, covalent and irreversible inhibitor of KRAS G12C, MRTX1257 inhibited KRAS dependent ERKphosphorylation in the H358cell assay with an IC50= 900 pM. 了解更多

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NG52

Catalog No. A12494
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Cell cycle-regulating kinase 抑制剂

NG52 (Compound 52)是细胞周期调节激酶Cdc28p（IC50 = 7 μM）和相关Pho85p激酶（IC50 = 2 μM）的有效，可渗透细胞，可逆，选择性和ATP兼容的抑制剂。了解更多

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EHop-016

Catalog No. A12740
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Rac GTPase Inhibitor

EHop-016 is a potent and specific inhibitor of Rac1 and Rac3 GTPase activity that inhibits Vav2 interaction with Rac, Rac-activated PAK1, lamellipodia formation, and cell migration. 了解更多

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