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搜索结果：“MK 1775”

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CMK

Catalog No. A11368
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RSK2 kinase inhibitor

CMK is a RSK2 kinase inhibitor which exhibits similar potency but less chemical stability compared with FMK. 了解更多

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FMK

Catalog No. A11423
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RSK 抑制剂

FMK是p90核糖体蛋白S6激酶RSK1和RSK2的有效，高度特异性和不可逆的抑制剂。Fmk结合在CTKD ATP结合位点，并抑制Ser386处的RSK自磷酸化。Fmk诱导人类表达FGFR3的t（4; 14）阳性多发性骨髓瘤细胞发生明显凋亡。了解更多

Product Citations (1)

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- Huang-Ming Chang, .et al. FGF23 ameliorates ischemia-reperfusion induced acute kidney injury via modulation of endothelial progenitor cells: targeting SDF-1/CXCR4 signaling, Cell Death Dis, 2021, Apr 17;12(5):409 PMID: 33866326

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