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LY294002

Catalog No. A10547
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PI3K 抑制剂

LY294002是PI3k抑制剂（IC50约为10μM）和酪蛋白激酶II抑制剂。了解更多

Product Citations (7)

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- Ming-Chun Hung, .et al. AKT phosphorylation as a predictive biomarker for PI3K/mTOR dual inhibition-induced proteolytic cleavage of mTOR companion proteins in small cell lung cancer, Cell Biosci, 2022, 12: 122 PMID: 35918763
- Chien-Feng Li, .et al. EMP2 induces cytostasis and apoptosis via the TGF β/SMAD/SP1 axis and recruitment of P2RX7 in urinary bladder urothelial carcinoma, Cell Oncol (Dordr), 2021, Aug 2 PMID: 34339014
- Hiroharu Sakai, .et al. BRAP2 inhibits the Ras/Raf/MEK and PI3K/Akt pathways in leukemia cells, thereby inducing apoptosis and inhibiting cell growth, Exp Ther Med, 2021, March 5 PMID: 33747195
- Cheng Zhou, .et al. GLI1 reduces drug sensitivity by regulating cell cycle through PI3K/AKT/GSK3/CDK pathway in acute myeloid leukemia, Cell Death Dis, 2021, Mar 3;12(3):231 PMID: 33658491
- Daniel Limonta, .et al. Fibroblast growth factor 2 enhances Zika virus infection in human fetal brain, J Infect Dis, 2019, 2019 PMID: 30799482
- Lv H, .et al. CXCL8 gene silencing promotes neuroglial cells activation while inhibiting neuroinflammation through the PI3K/Akt/NF-κB-signaling pathway in mice with ischemic stroke, J Cell Physiol, 2018, Oct 26 PMID: 30362547
- Hui Liang, .et al. Targeting the PI3K/AKT pathway via GLI1 inhibition enhanced the drug sensitivity of acute myeloid leukemia cells, Sci Rep, 2017, 7: 40361 PMID: 28098170
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LY 303511

Catalog No. A15147
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PI3K 抑制剂

LY303002是LY294002的非活性类似物，是一种mTOR抑制剂，不抑制PI3-K。了解更多

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SF1126

Catalog No. A12704
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Pan PI3K 抑制剂

SF1126是一种水溶性小分子前药，包含泛PI3K/mTOR抑制剂LY294002/SF1101与含RGD的四肽SF1174共轭，具有潜在的抗肿瘤和抗血管生成活性。了解更多

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