“MK-2206 dihydrochloride”的搜索结果
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ROCK inhibitor
Y-33075 dihydrochloride is a selective ROCK inhibitor with an IC50 of 3.6 nM.
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ROCK 抑制剂
SR 3677 dihydrochloride是一种有效的选择性Rho激酶抑制剂(ROCK-II和ROCK-I的IC50值分别为3和56 nM)。
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ROCK 抑制剂
HA-1077 dihydrochloride通过充当细胞内Ca2+拮抗剂来抑制血管平滑肌收缩。
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ROCK 抑制剂
H-1152 dihydrochloride是一种异喹啉磺酰胺衍生物,是Rho激酶的一种更特异,更强且可透过膜的抑制剂,Ki值为1.6 nM,但对其他丝氨酸/苏氨酸激酶的抑制作用较弱。
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CDK4/CDK6 inhibitor
Lerociclib dihydrochloride (G1T38 dihydrochloride) is a potent and selective inhibitor of CDK4/CDK6, with IC50s of 1 nM and 2 nM for CDK4/CyclinD1 and CDK6/CyclinD3, respectively.
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CHK1 inhibitor
GDC-0575 dihydrochloride (ARRY-575 dihydrochloride) is an orally bioavailable CHK1 inhibitor, with an IC50 of 1.2 nM, and has antitumor activity.
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