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Crisaborole (AN2728)
Catalog No. A12776 PDE4 抑制剂?AN2728是一种局部给药的含硼抗炎化合物，可抑制PDE4活性，从而抑制TNFalpha，IL-12，IL-23和其他细胞因子的释放。抑制PDE4的 IC50 值为0.49 μM。 了解更多 -
Rosiglitazone (BRL-49653)
Catalog No. A10807 PPAR 激动剂Rosiglitazone (BRL-49653)是有效的降糖药，也是有效的噻唑烷二酮类胰岛素增敏剂，在大鼠，3T3-L1和人体脂肪细胞中IC50分别为12，4和9 nM。Rosiglitazone是PPAR-gamma的配体，对PPAR-alpha没有结合力。 了解更多 -
Tesaglitazar
Catalog No. A20891 PPAR alpha/gamma agonistTesaglitazar is a dual peroxisome proliferator-activated receptor (PPAR) alpha/gamma agonist that is more potent on PPARγ than on PPARα, with EC50s of 13.4 μM and 3.6 μM for rat PPARα and human PPARα, respectively. 了解更多 -
Chiglitazar
Catalog No. A12701 PPARα/γ dual agonistChiglitazar is a PPARα/γ dual agonist, with EC50s of 1.2, 0.08, 1.7 μM for PPARα, PPARγ and PPARδ, respectively. 了解更多 -
NXT629
Catalog No. A18771 PPAR-α antagonistNXT629 is a potent, selective, and competitive PPAR-α antagonist, with an IC50 of 77 nM for human PPARα, shows high selectivity over other nuclear hormone receptor, such as PPARδ, PPARγ, ERβ, GR and TRβ, IC50s are 6.0, 15, 15.2, 32.5 and >100 μM, respectively. 了解更多 -
Peliglitazar racemate
Catalog No. A21411 dual α/γ PPAR activatorPeliglitazar racemate is the racemate of Peliglitazar. Peliglitazar is a novel dual α/γ PPAR activator. 了解更多 -
Indeglitazar
Catalog No. A21148 PPAR agonistIndeglitazar is an orally available peroxisome proliferator-activated receptor (PPAR) pan-agonist for all three PPAR subtypes alpha (α), delta (δ) and gamma (γ). 了解更多 -
Terphenyllin
Catalog No. A18967 Terphenyllin is a naturally abundant p-terphenyl metabolite isolated from the coral derived fungus Aspergillus candidus, has signi?cant α-glucosidase inhibitory activity. 了解更多 -
Celgosivir
Catalog No. A13118 -
CUDC-305 (DEBIO-0932 )
Catalog No. A12648 HSP90 抑制剂CUDC-305 (DEBIO-0932) 是一种新型的热休克蛋白90（HSP90）抑制剂，对HSP90 alpha/beta具有很强的亲和力，对HSP90α和HSP90β的IC50值分别为100和103nM。具有很高的口服生物利用度，并且对多种癌细胞系均具有强大的抗增殖活性（平均IC50为220 nmol/L）。包括许多对护理标准（SOC）药物有抵抗力的非小细胞肺癌（NSCLC）细胞系。 了解更多
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