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mTOR 抑制剂
CC-223是一种有效的mTOR激酶抑制剂(IC50 = 16 nM),其敏感性是相关脂质激酶PI3K-alpha(IC50 = 4 uM)的> 150倍。
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dual PI3K and mTOR kinase inhibitor
Dactolisib Tosylate (BEZ235 Tosylate) is a dual PI3K and mTOR kinase inhibitor with IC50 values of 4, 75, 7, 5 nM for PI3Kα, β, γ, δ, respectively. Dactolisib Tosylate (BEZ235 Tosylate) inhibits mTORC1 and mTORC2.
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PI3K/mTOR inhibitor
NSC781406 is a highly potent PI3K and mTOR inhibitor with an IC50 of 2 nM for PI3Kα.
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