“sb269970 hcl”的搜索结果

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  1. SKF 89976A HCl

    Catalog No. A10849
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    GABA uptake 抑制剂
    SKF 89976A HCl是一种有效的GABA吸收抑制剂,hGAT-1,rGAT-2,hGAT-3和hBGT-1的IC50分别为0.13、550、944和7210μM。 了解更多
  2. Biperiden HCl

    Catalog No. A10147
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    Muscarinic receptor antagonist
    Biperiden HCl是毒蕈碱受体拮抗剂,对M1亚型表现出一定的选择性。 了解更多
  3. Ticlopidine HCl

    Catalog No. A11690
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    Ticlopidine是一种二磷酸腺苷(ADP)受体抑制剂。它通过阻断ADP受体来改变血小板膜的功能,从而抑制血小板聚集。这防止了糖蛋白IIb/IIIa的构象变化,从而使血小板与血纤蛋白原结合。 了解更多
  4. Phenoxybenzamine hydrochloride

    Catalog No. A10719
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    α-adrenergic (AR) 拮抗剂/CaM 抑制剂
    Phenoxybenzamine hydrochloride是一种细胞可渗透的,非特异性的,不可逆的α-肾上腺素(AR)拮抗剂,也可作为CaM抑制剂。 了解更多
  5. Pitofenone Hydrochloride

    Catalog No. A17053
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    Antispasmodic Agent
    Pitofenone Hydrochloride是抗痉化合物。它是乙酰胆碱酯酶活性的有效抑制剂。 了解更多
  6. Mecamylamine Hydrochloride

    Catalog No. A17884
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    nAChR antagonist
    Mecamylamine hydrochloride is a nAChR antagonist previously used to treat hypertension. It displays a wide variety of activities, including reducing depression-like behaviors in subjects with Tourette's syndrome and improving rates of smoking cessation. 了解更多
  7. Tacrine HCl

    Catalog No. A17374
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    AChE & butyrylcholinesterase inhibitor
    Tacrine is a derivative of aminoacridine that functions as an inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (IC50s = 31 and 26.5 nM, respectively). 了解更多
  8. Cevimeline hydrochloride

    Catalog No. A18092
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    mAChR agonist
    Cevimeline (Evoxac) Hcl is a parasympathomimetic and muscarinic agonist, with particular effect on M3 receptors; used in the treatment of dry mouth associated with sjogren's syndrome. 了解更多
  9. Dimebon 2HCl

    Catalog No. A10312
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    Neuroprotectant
    Dimebon dihydrochloride是一种非选择性的抗组胺药,具有增强认知能力。 了解更多
  10. 5-Iodo-A-85380 2HCl

    Catalog No. A13639
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    nAChR 激动剂
    5-Iodo-A-85380 2HCl是针对a4b2和a6b2烟碱乙酰胆碱受体的强效亚型选择性激动剂。 了解更多
  11. GW791343 trihydrochloride

    Catalog No. A21204
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    P2X7 allosteric modulator
    GW791343 3Hcl is a P2X7 allosteric modulator; exhibits species-specific activity and acts as a negative allosteric modulator of human P2X7 (pIC50 = 6.9 - 7.2). 了解更多
  12. Tacrine HCl Hydrate

    Catalog No. A16970
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    AChE and BChE 抑制剂
    Tacrine hydrochloride hydrate是乙酰(AChE)和丁酰胆碱酯酶(BChE)的抑制剂,IC50分别为31 nM和25.6 nM。 了解更多
  13. Adiphenine HCl

    Catalog No. A11716
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    AChR抑制剂
    Adiphenine Hydrochloride是烟碱受体抑制剂,IC50为15μM,用作解痉药物。 了解更多
  14. Diphenidol HCl

    Catalog No. A14244
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    M2/M3 拮抗剂
    Diphenidol HCl是毒蕈碱M2和M3受体的有效拮抗剂,pKb为6.72和7.02。 了解更多
  15. Deoxyvasicine HCl

    Catalog No. A13925
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    AChE 抑制剂
    Desoxypeganine hydrochloride是一种AChE(乙酰胆碱酯酶)抑制剂,已用于治疗阿尔茨海默氏痴呆症。 了解更多
  16. Tropisetron HCL

    Catalog No. A14375
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    5-HT3 receptor 拮抗剂
    Tropisetron HCL是选择性的5-HT3受体拮抗剂和α7烟碱样受体激动剂,对5-HT3受体的IC50为70.1±0.9 nM。 了解更多
  17. ABT-418 HCl

    Catalog No. A13688
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    nAChR 激动剂
    ABT-418 HCl是神经元烟碱型乙酰胆碱受体激动剂。 了解更多
  18. Fexofenadine HCl

    Catalog No. A11859
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    COX 抑制剂/histamine H1 receptor 激动剂
    Fexofenadine Hydrochloride是一种抗组胺药,可抑制Cox-1,Cox-2,并且是组胺H1受体激动剂,IC50为246 nM。 了解更多
  19. GW791343 HCl

    Catalog No. A11107
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    P2X7 modulator
    GW791343 HCl充当人P2X7的负变构调节剂(pIC50 = 6.9-7.2)和大鼠P2X7的正变构调节剂。 了解更多
  20. A-438079 HCl

    Catalog No. A12597
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    P2X7 receptor 拮抗剂
    A-438079 HCl是一种竞争性P2X7受体拮抗剂(抑制人重组P2X7细胞系中Ca2+流入的pIC50 = 6.9)。在其他P2受体上没有活性(IC50 > 10 uM)。 了解更多

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