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MRK-016
Catalog No. A12046 GABAA α5 receptor agonistMRK-016 is a selective, orally bioavailable inverse agonist of GABAA α5 receptor, with an EC50 of 3 nM for GABAA α5, and Kis of 0.83, 0.85, 0.77?and 1.4?nM for human?GABAA?α1β3γ2, GABAA?α2β3γ2, GABAA?α3β3γ2, and GABAA?α5β3γ2, respectively; MRK-016 also readily penetrates the CNS. 了解更多 -
alpha-Amyloid Precursor Protein Modulator
Catalog No. A13094 α-淀粉样前体蛋白调节剂是细胞可渗透的苯并内酰胺衍生的PKC激活剂（PKCα的Ki = 11.9 nM），即使在人类原纤维中为100 nM时，也能有效增强淀粉样前体蛋白（APP）的非淀粉样生成性α-加工。 了解更多 -
Varenicline Hydrochloride
Catalog No. A21539 α4β2 nAChR partial agonistVarenicline Hydrochloride (CP 526555 hydrochloride) is a high affinity, selective α4β2 nicotine acetylcholine receptor (nAChR) partial agonist and full α7 nAChR agonist. 了解更多 -
Basmisanil
Catalog No. A21321 GABAAα5 modulatorBasmisanil is a highly selective GABAAα5 negative allosteric modulator. 了解更多 -
(-)-(S)-B-973B
Catalog No. A18761 α7 nAChR modulator-)-(S)-B-973B is a potent allosteric agonist and positive allosteric modulator of α7 nAChR, with antinociceptive activity. 了解更多 -
Anisodamine
Catalog No. A18215 alpha-1 adrenergic receptors / mAChRs inhibitorAnisodamine is an inhibitor of alpha-1 adrenergic receptors and mAChRs isolated from Chinese solanacea plant. 了解更多 -
Gaboxadol hydrochloride
Catalog No. A21730 GABAA receptors agonistGaboxadol hydrochloride (Lu 02-030 hydrochloride) is a selective agonist at GABAA receptors that contain α4-δ subunits, and has anxiolytic and sedative effects. 了解更多 -
Eicosatetraynoic acid
Catalog No. A19008 COX/LOX inhibitorEicosatetraynoic acid (ETYA) is a nonspecific inhibitor of cyclooxygenase and lipoxygenase (ID50=8 μM and 4 μM, respectively). Eicosatetraynoic acid (ETYA) activates PPARα and PPARγ chimeras at 10 ?M?? 了解更多
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