“alpha ergocryptine”的搜索结果
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Integrin alpha4beta1 抑制剂
BIO-1211是整联蛋白alpha4beta1抑制剂。
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αV integrins 抑制剂
CWHM 12可以抑制所有5个alpha V整联蛋白。CWHM12不仅以与遗传删除方法相同的方式预防纤维化,还可以防止肝和肺中现有纤维化的进展,并逆转了由纤维化对这些器官造成的某些损害。
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α4β1/α4β7 integrin 拮抗剂
Firategrast (SB 683699)是一种口服可生物利用的alpha4 beta1/alpha4 beta7整联蛋白拮抗剂,旨在减少淋巴细胞向中枢神经系统(CNS)的运输。
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- Higuchi S, .et al. Inhibition of the integrin signal constitutes a mouse iPS cell niche, Dev Growth Differ, 2016, Sep;58(7):586-99 PMID: 27633818
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αVβ3 integrin inhibitor
Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with an IC50 of 20 nM.
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α4 integrin receptor inhibitor
Carotegrast is an orally available α4 integrin receptor inhibitor with anti-inflammatories activities.
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integrin α5β1 antagonist
ATN-161 trifluoroacetate salt is a novel integrin α5β1 antagonist, which inhibits angiogenesis and growth of liver metastases in a murine model.
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integrin α5β1 antagonist
ATN-161 is a novel integrin α5β1 antagonist, which inhibits angiogenesis and growth of liver metastases in a murine model.
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αvβ3 integrin antagonist
MK-0429 (L-000845704) is an orally active, potent, selective and nonpeptide αvβ3 integrin antagonist with an IC50 of 80 nM.
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integrin αvβ3 antagonist
Integrin Antagonists 27 is a small molecule integrin αvβ3 antagonist with binding affinity of 18 nM, as s novel anticancer agent.
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α4β1/α9β1 抑制剂
R-BC154是高亲和力的荧光α4β1/α9 9β1抑制剂。
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α9β1/α4β1 integrin 抑制剂
BOP sodium salt是新型的双重alpha9beta1/alpha4beta1整联蛋白抑制剂。
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Integrin receptor antagonist
GLPG0187 is a broad spectrum integrin receptor antagonist with antitumor activity; inhibits αvβ1-integrin with an IC50 of 1.3 nM.
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α1β1 抑制剂
Obtustatin是高度有效的整联蛋白α1β1抑制剂(α1β1与IV型胶原的结合的IC 50 = 0.8 nM)。与α2β1,βIIbβ3,αvβ3,α4β1,β5β6,α9β1和α4β7相比,α1β1具有选择性。在鸡绒膜尿囊炎模型中抑制FGF2刺激的血管生成。在Lewis肺癌的协同小鼠模型中显示抗肿瘤功效;阻止人黑素瘤在裸鼠中的生长。
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α2β1 integrin 抑制剂
BTT-3033是α2β1整联蛋白抑制剂。
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