“MK-2206 dihydrochloride”的搜索结果
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5-HT1D receptor 拮抗剂
BRL-15572是一种选择性的h5-HT1D拮抗剂,相对于h5-HT1B表现出60倍的选择性,对一系列其他受体类型的亲和力很小或没有亲和力。
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DAT and SLC6A2 抑制剂
GBR-12935 dihydrochloride是一种有效的选择性多巴胺再摄取抑制剂。
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5-HT1A and α1-adrenergic receptor 拮抗剂
Naftopidil 2HCl是选择性5-HT1A和α1-肾上腺素能受体拮抗剂,IC50分别为0.1μM和0.2μM。
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dopamine re-uptake 抑制剂
Vanoxerine 2HCl (GBR-12909)是哌嗪衍生物,是一种有效的、选择性的多巴胺摄取(dopamine uptake)抑制剂。
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Cetirizine Dihydrochloride是第二代抗组胺药,是羟嗪的主要代谢产物,是用于治疗过敏,花粉症,血管性水肿和荨麻疹的消旋选择性H1受体反向激动剂。
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Pramipexole dihydrochloride是对D3受体表现出选择性的多巴胺受体激动剂。
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dopamine uptake 抑制剂
GBR 12783 dihydrochloride是一种非常有效的选择性多巴胺摄取抑制剂(抑制大鼠纹状体突触体中[3H]-多巴胺摄取的IC50为1.8 nM)。
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H3 receptor 拮抗剂
Bavisant dihydrochloride是一种人类H3受体的高选择性,口服活性拮抗剂。
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Dopamine receptor 拮抗剂
cis-(Z)-Flupentixol dihydrochloride是多巴胺受体拮抗剂、抗精神病药物、抗精神病药物。
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dopamine 激动剂
Dexpramipexole dihydrochloride是一种神经保护剂和弱非麦角灵多巴胺激动剂。
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H3 receptor 拮抗剂
Bavisant dihydrochloride hydrate是人类H3受体的高度选择性口服活性拮抗剂。
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NK1 receptor antagonist
Vofopitant dihydrochloride (GR 205171A) is a potent, selective and orally available tachykinin neurokinin 1(NK1) receptor antagonist.
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Dopamine Receptor 激动剂
Pramipexole dihydrochloride monohyrate是非麦角灵类的多巴胺激动剂,适用于治疗早期帕金森氏病(PD)和不安腿综合征(RLS)。
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L-isomer of cetirizine and histamine H1 receptor antagonist
Levocetirizine dihydrochloride is a L-isomer of cetirizine and histamine H1 receptor antagonist. It incrases levels of CD4+ CD25+ T cells and decreases levels of eosinophils, decreasing allergy symptoms.
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5-HT1A receptor agonist
Lesopitron dihydrochloride is a full and selective 5-HT1A receptor agonist with IC50 of 125 nM in rat hippocampal membranes.
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S1P inhibitor
PF429242 dihydrochloride is a reversible and competitive S1P inhibitor with an IC50 of 175 nM.
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dopamine D2 receptor antagonist
JNJ-37822681 dihydrochloride is a potent, specific, centrally active, fast-dissociating dopamine D2 receptor antagonist with a moderate binding affinity for the dopamine D2L receptor (Ki =158 nM), which has potential for the treatment of schizophrenia and bipolar disorder.
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dopamine D4 receptor partial agonist
Ro 10-5824 dihydrochloride is a selective dopamine D4 receptor partial agonist, with Ki of 5.2 nM.
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dopamine D3 receptor antagonist
SB-277011 dihydrochloride (SB-277011A dihydrochloride) is a potent, selective, orally bioavailable and brain penetrate dopamine D3 receptor antagonist, with pKis of 8.0, 6.0, <5.2 and 5.9 for D3, D2, 5-HT1B, and 5-HT1D receptors, respectively.
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