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14 个项目
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Vericiguat
Catalog No. A21031 guanylate cyclase stimulatorVericiguat (BAY1021189) is a potent, orally available and soluble guanylate cyclase stimulator. 了解更多 -
Vofopitant dihydrochloride
Catalog No. A21543 NK1 receptor antagonistVofopitant dihydrochloride (GR 205171A) is a potent, selective and orally available tachykinin neurokinin 1(NK1) receptor antagonist. 了解更多 -
Masupirdine mesylate
Catalog No. A21409 5-HT6 receptor antagonistMasupirdine mesylate (SUVN-502 mesylate) is a potent, selective, orally bioavailable, and brain penetrant 5-HT6 receptor antagonist (Ki of 2.04 nM for human 5-HT6 receptor). 了解更多 -
SB-277011 dihydrochloride
Catalog No. A21353 dopamine D3 receptor antagonistSB-277011 dihydrochloride (SB-277011A dihydrochloride) is a potent, selective, orally bioavailable and brain penetrate dopamine D3 receptor antagonist, with pKis of 8.0, 6.0, <5.2 and 5.9 for D3, D2, 5-HT1B, and 5-HT1D receptors, respectively. 了解更多 -
Basimglurant
Catalog No. A21225 mGlu5 negative allosteric modulatorBasimglurant (RG7090) is a potent, selective and orally available mGlu5 negative allosteric modulator with a Kd of 1.1 nM. 了解更多 -
L-371,257
Catalog No. A21219 oxytocin receptor antagonistL-371,257 is an orally bioavailable, non-blood-brain barrier penetrant, selective and competitive antagonist of oxytocin receptor (pA2=8.4) with high affinity at both the oxytocin receptor (Ki=19 nM) and vasopressin V1a receptor (Ki=3.7 nM). 了解更多 -
β3-AR agonist 1
Catalog No. A12777 β3-adrenergic receptor agonistβ3-AR agonist 1 (compound 15) is a highly potent, selective, and orally available β3-adrenergic receptor (β3-AR) agonist (EC50=18 nM), being inactive to β1-, β2-, and α1A-AR (β1/β3, β2/β3, and α1A/β3>556-fold). 了解更多 -
Alosetron (Hydrochloride(1:X))
Catalog No. A11309 Serotonin 5HT3-receptor antagonistAlosetron Hydrochloride(1:X) (GR 68755 Hydrochloride(1:X)) is a Serotonin 5HT3-receptor antagonist that is used in treatment of irritable bowel syndrome. 了解更多 -
Trimebutine maleate
Catalog No. A18115 ?- opioid receptor agonistTrimebutine Maleate is a drug with antimuscarinic and weak mu opioid agonist effects. Trimebutine Maleate modulates the calcium and potassium channels, relieves abdominal pain in patients with irritable bowel syndrome. 了解更多 -
Tianeptine sodium
Catalog No. A10931
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