“MK-2206 dihydrochloride”的搜索结果
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p38 MAPK 抑制剂
DBM 1285 dihydrochloride是p38 MAPK抑制剂。在巨噬细胞和体内抑制p38磷酸化和LPS诱导的TNF-α产生。
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p38 MAPK 抑制剂
SKF 86002 Dihydrochloride是p38 MAP激酶的抑制剂(IC50 = 0.1-1 uM)。有效抑制人单核细胞中LPS诱导的IL-1和TNF-α的产生(IC50 = 1 uM)。
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Raf 抑制剂
ML 786 dihydrochloride是一种有效的Raf激酶抑制剂(B-RafV600E,C-Raf和野生型B-Raf的IC50值分别为2.1、2.5和4.2 nM)。
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Raf kinase inhibitor
B-Raf inhibitor 1 dihydrochloride is a potent Raf kinase inhibitor with Kis of 1 nM, 1 nM, and 0.3 nM for B-RafWT, B-RafV600E, and C-Raf, respectively.
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p38α MAPK inhibitor
MW-150 dihydrochloride dihydrate (MW01-18-150SRM dihydrochloride dihydrate) is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM.
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