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“glucagon receptor”的搜索结果

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  1. MPEP
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    MPEP

    Catalog No. A12589
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    mGlu5 receptor 拮抗剂
    MPEP是mGlu5受体亚型（IC50 = 36 nM）的有效且高度选择性的非竞争性拮抗剂，并且是mGlu4受体的正构构调节剂。 了解更多
  2. LY 379268
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    LY 379268

    Catalog No. A13123
    mGlu2 receptor 激动剂
    LY 379268是高选择性的II类mGlu受体激动剂（对于hmGlu2和hmGlu3而言，EC50值分别为2.69和4.48 nM），其选择性是I类和III类受体的80倍以上。 了解更多
  3. MPEP HCl
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    MPEP HCl

    Catalog No. A13236
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    mGlu5 receptor 拮抗剂
    MPEP HCl是对mGlu5a受体亚型（IC50 = 36 nM）的有效，高度选择性的非竞争性拮抗剂，但在浓度高达30 uM的mGlu1b受体上无激动剂或拮抗剂活性。 了解更多
  4. Ibotenic Acid
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    Ibotenic Acid

    Catalog No. A14006
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    NMDA& mGlu receptor 激动剂
    Ibotenic Acid是最初从鹅膏菌属物种中分离出来的一种神经兴奋性氨基酸，它起着NMDA和代谢型谷氨酸受体激动剂的作用。 了解更多
  5. Kainic acid monohydrate
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    Kainic acid monohydrate

    Catalog No. A13485
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    Kainate receptor 激动剂
    Kainic acid monohydrate是海藻酸酯类离子型谷氨酸受体激动剂。可在体内诱发癫痫发作和神经退行性变，也已用于在啮齿动物中诱发实验性癫痫和检查兴奋性诱发的神经元凋亡机制。 了解更多
  6. CBiPES HCl
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    CBiPES HCl

    Catalog No. A15811
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    mGlu2 receptor modulator
    CBiPES HCl是mGluR-2的选择性正变构调节剂，IC50值为98.2 nM。 了解更多
  7. VU6005649
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    VU6005649

    Catalog No. A17023
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    CNS penetrant mGlu7/8 receptor 激动剂
    VU6005649是一种CNS渗透性mGlu7/8受体激动剂，对mGlu7受体和mGlu8受体的EC50分别为0.65 μM和2.6 μM。 了解更多
  8. VU0652835
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    VU0652835

    Catalog No. A18885
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    mGlu5 modulator
    VU0652835 is a metabotropic glutamate receptor subtype 5 (mGlu5) negative allosteric modulator with an IC50 of 81 nM. 了解更多
  9. ADX88178
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    ADX88178

    Catalog No. A20922
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    mGluR4 PAM
    ADX88178 is a potent metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) with an EC50 of 4 nM for human mGluR4. 了解更多
  10. LY2794193
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    LY2794193

    Catalog No. A19131
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    mGlu3 receptor agonist
    LY2794193 is a highly potent and selective mGlu3 receptor agonist (hmGlu3 Ki=0.927 nM??EC50=0.47 nM; hmGlu2 Ki=412 nM??EC50=47.5 nM). 了解更多
  11. Lu AF21934
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    Lu AF21934

    Catalog No. A12140
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    mGlu4 receptor modulator
    Lu AF21934 is a selective and brain-penetrant mGlu4 receptor positive allosteric modulator with an IC50 of 500 nM for human mGlu4. 了解更多
  12. LY2812223
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    LY2812223

    Catalog No. A21100
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    mGlu2 receptor agonist
    LY2812223 is a highly potent, functionally selective mGlu2 receptor agonist with mGlu2 binding affinity for mGlu2 and mGlu3 (Ki=144 nM and 156 nM, respectively). 了解更多
  13. TCN238
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    TCN238

    Catalog No. A21191
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    mGlu4 receptor modulator
    TCN238 is a positive allosteric mGlu4 receptor modulator with an EC50 of 1 μM. 了解更多
  14. Mavoglurant
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    Mavoglurant

    Catalog No. A21223
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    mGlu5 receptor antagonist
    Mavoglurant is a structurally novel, non-competitive mGlu5 receptor antagonist, has an IC50 of 30 nM in a functional assay with human mGluR5. 了解更多
  15. Mavoglurant racemate
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    Mavoglurant racemate

    Catalog No. A21799
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    mGlu5 receptor antagonist
    Mavoglurant (racemate) is the racemate of mavoglurant. Mavoglurant is a novel, non-competitive mGlu5 receptor antagonist. 了解更多
  16. Methoxy-PEPy
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    Methoxy-PEPy

    Catalog No. A21899
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    mGlu5 receptor antagonist
    Methoxy-PEPy is a potent and highly selective mGlu5 receptor antagonist with IC50 of 1 nM. 了解更多
  17. Eglumegad
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    Eglumegad

    Catalog No. A21005
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    group II (mGlu2/3) receptor agonist
    Eglumegad (LY354740) is a highly potent and selective group II (mGlu2/3) receptor agonist with IC50s of 5 and 24 nM on transfected human mGlu2 and mGlu3 receptors, respectively. 了解更多
  18. VU 0361737
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    VU 0361737

    Catalog No. A12467
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    mGlu4 receptors modulator
    VU 0361737是mGluR-4的选择性正变构调节剂（人和大鼠受体的EC50值分别为240和110 nM）。 了解更多
  19. VU 0364770
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    VU 0364770

    Catalog No. A12139
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    mGlu4 receptors modulator
    VU 0364770是mGlu4受体的正变构调节剂，在表达mGlu4的HEK 293细胞中EC50值为290 nM。 了解更多
  20. O-Phospho-L-serine
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    O-Phospho-L-serine

    Catalog No. A21159
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    group III mGluR receptors agonist
    O-Phospho-L-serine is the immediate precursor to L-serine in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8); O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist for mGluR2. 了解更多
  21. L-APB
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    L-APB

    Catalog No. A21872
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    mGluRs M3 agonist
    L-APB is a potent and specific agonist for the group III mGluRs, with EC50s of 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6 and mGlu7 receptors, respectively. 了解更多

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