“MK-2206 dihydrochloride”的搜索结果

产品 1 到 50 共 116个

每页
页面:
  1. 1
  2. 2
  3. 3

设置升序顺序
  1. Mitoxantrone Hydrochloride

    Catalog No. A10596
    Quick View
    Mitoxantrone Dihydrochloride是一种抗病毒,抗菌,抗原生动物,免疫调节和抗肿瘤细胞抑制性蒽醌衍生物。 了解更多
  2. Quinacrine 2HCl

    Catalog No. A13242
    Quick View
    Quinacrine dihydrochloride是组胺N-甲基转移酶抑制剂。 了解更多
  3. Nitrarine 2HCl

    Catalog No. A13911
    Quick View
    Nitrarine dihydrochloride在实验性心律不齐中具有镇静作用。它的抗心律不齐特性是由于其对膜的稳定作用及其冠状动脉扩张作用。Nitrarine dihydrochloride是新卡因胺和奎尼丁的3-4倍,其效果持续时间是这些产品的2-5倍。 了解更多
  4. K-7174 2HCl

    Catalog No. A15446
    Quick View
    Cell adhesion 抑制剂
    K-7174 dihydrochloride是一种新型的细胞粘附抑制剂;抑制由IL-1beta或TNF-alpha诱导的血管细胞粘附分子1(VCAM-1)的表达。 了解更多
  5. Sardomozide HCl

    Catalog No. A15987
    Quick View
    polyamine synthesis 抑制剂
    Sardomozide dihydrochloride是第二代多胺合成抑制剂,可抑制多胺生物合成酶S-腺苷甲硫氨酸脱羧酶(SAMDC)的活性。 了解更多
  6. HA-100 (C1)

    Catalog No. A17019
    Quick View
    PKs 抑制剂
    HA-100 dihydrochloride是具有添加的哌嗪基磺酰基的异喹啉化合物,可充当蛋白激酶(PKs)的抑制剂,包括PKA,PKC和PKG(IC50分别为8、12和4 μM)。 了解更多
  7. BRL-15572 dihydrochloride

    Catalog No. A11178
    5-HT1D receptor 拮抗剂
    BRL-15572是一种选择性的h5-HT1D拮抗剂,相对于h5-HT1B表现出60倍的选择性,对一系列其他受体类型的亲和力很小或没有亲和力。 了解更多
  8. Meclizine 2HCl

    Catalog No. A11700
    Quick View
    Meclizine是人类的孕烷X受体(hPXR)激动剂。它具有抗胆碱能,中枢神经系统抑制作用和局部麻醉作用。其止吐和抗眩晕作用尚不完全清楚,但其主要的抗胆碱能特性是部分原因。 了解更多
  9. NNC 55-0396

    Catalog No. A15188
    Quick View
    Calcium channel blocker
    NNC 55-0396是Mibefradil衍生物,是一种高度选择性的T型钙通道阻滞剂;分别在INS-1细胞中抑制Cav3.1 T型通道和HVA电流的IC50值为6.8和> 100μM。 了解更多
  10. GTS-21 (DMBX-A)

    Catalog No. A15950
    Quick View
    nAChR 激动剂
    GTS-21 dihydrochloride (DMBX-A)是一种选择性的α7烟碱乙酰胆碱受体激动剂,最近已被确定为一种有希望的炎症治疗方法。 了解更多
  11. Cefotiam hydrochloride

    Catalog No. A17481
    Quick View
    anti-microbial
    Cefotetan Hydrochloride is a second-generation cephalosporin that is active against some strains of β-lactamase producing bacteria. It shows anti-microbial activity against Gram-positive and Gram-negative bacteria; it is more efficacious against Gram-negative and anaerobic bacteria 了解更多
  12. IT1t

    Catalog No. A20408
    Quick View
    CXCR4 antagonist
    IT1t is a potent CXCR4 antagonist; inhibits CXCL12/CXCR4 interaction with an IC50 of 2.1 nM. 了解更多
  13. Varenicline HCl

    Catalog No. A22519
    Quick View
    Varenicline is a nicotinic receptor partial agonist. 了解更多
  14. CFI-400437 HCl

    Catalog No. A22463
    Quick View
    CFI-400437 is a potent and selective inhibitor of polo-like kinase 4 (PLK4). 了解更多
  15. GBR-12935 2HCl

    Catalog No. A11937
    Quick View
    DAT and SLC6A2 抑制剂
    GBR-12935 dihydrochloride是一种有效的选择性多巴胺再摄取抑制剂。 了解更多
  16. Flurazepam dihydrochloride

    Catalog No. A13279
    Quick View
    Flurazepam dihydrochloride具有抗焦虑,抗惊厥,镇静和骨骼肌松弛的特性。 了解更多
  17. Nolatrexed Dihydrochloride

    Catalog No. A13261
    Quick View
    Thymidylate synthase 抑制剂
    Nolatrexed Dihydrochloride是一种抗叶酸胸苷酸合酶抑制剂。 了解更多
  18. NVP DPP 728 dihydrochloride

    Catalog No. A15320
    Quick View
    DPP-4 抑制剂
    NVP DPP 728 dihydrochloride是一种有效的活性二肽基肽酶(DPP)-IV抑制剂,Ki和IC50值分别为11 nM和14 nM。 了解更多
  19. CP 31398 dihydrochloride

    Catalog No. A15346
    Quick View
    p53 stabilizer
    CP 31398 dihydrochloride是p53稳定剂。在具有突变型或野生型p53的癌细胞系中稳定p53的活性构象并提高p53的活性。在体内抑制小的人类肿瘤异种移植物的生长。 了解更多
  20. KX2-391 2HCl

    Catalog No. A11471
    Quick View
    Src 抑制剂
    Tirbanibulin dihydrochloride是首个靶向Src肽底物位点的临床Src抑制剂(拟肽类),在癌细胞系中GI50为9-60 nM。 了解更多
  21. Lomerizine dihydrochloride

    Catalog No. A16599
    Quick View
    L-type 拮抗剂
    Lomerizine dihydrochloride是L型和T型Ca2+通道和TRp5通道的拮抗剂,用于治疗偏头痛和眩晕。 了解更多
  22. Pyrithioxin dihydrochloride

    Catalog No. A18137
    Quick View
    neurotropic agent
    Pyrithioxine HCl is a neurotropic agent which reduces permeability of blood-brain barrier to phosphate. It has no vitamin B6 activity. 了解更多
  23. Pirenzepine dihydrochloride

    Catalog No. A17916
    Quick View
    M1 muscarinic receptor antagonist
    Pirenzepine dihydrochloride (LS519) is a selective M1 muscarinic receptor antagonist. 了解更多
  24. Naftopidil 2HCl

    Catalog No. A10619
    Quick View
    5-HT1A and α1-adrenergic receptor 拮抗剂
    Naftopidil 2HCl是选择性5-HT1A和α1-肾上腺素能受体拮抗剂,IC50分别为0.1μM和0.2μM。 了解更多
  25. Manidipine 2HCl

    Catalog No. A10554
    Quick View
    Manidipine dihydrochloride是Manidipine的HCl盐形式,Manidipine是Ca2+电流的钙通道阻滞剂,IC50为2.6 nM。 了解更多
  26. Vanoxerine 2HCl (GBR-12909)

    Catalog No. A10725
    Quick View
    dopamine re-uptake 抑制剂
    Vanoxerine 2HCl (GBR-12909)是哌嗪衍生物,是一种有效的、选择性的多巴胺摄取(dopamine uptake)抑制剂。 了解更多
  27. H 89 2HCl

    Catalog No. A11935
    Quick View
    PKA 抑制剂
    H 89 dihydrochloride是一种可渗透细胞的,选择性的,可逆的,具有ATP竞争性的有效蛋白激酶抑制剂。 了解更多
  28. Cetirizine Dihydrochloride

    Catalog No. A10195
    Quick View
    Cetirizine Dihydrochloride是第二代抗组胺药,是羟嗪的主要代谢产物,是用于治疗过敏,花粉症,血管性水肿和荨麻疹的消旋选择性H1受体反向激动剂。 了解更多
  29. Pramipexole dihydrochloride

    Catalog No. A12536
    Quick View
    Pramipexole dihydrochloride是对D3受体表现出选择性的多巴胺受体激动剂。 了解更多
  30. GBR 12783 dihydrochloride

    Catalog No. A13128
    Quick View
    dopamine uptake 抑制剂
    GBR 12783 dihydrochloride是一种非常有效的选择性多巴胺摄取抑制剂(抑制大鼠纹状体突触体中[3H]-多巴胺摄取的IC50为1.8 nM)。 了解更多
  31. BAY 61-3606 dihydrochloride

    Catalog No. A15017
    Quick View
    Syk 抑制剂
    BAY 61-3606 dihydrochloride是一种有效的Syk激酶抑制剂(Ki = 7.5 nM)。 了解更多
  32. Inolitazone dihydrochloride

    Catalog No. A15129
    Quick View
    PPARγ 激动剂
    Inolitazone dihydrochloride是一种新型的高亲和力PPARγ激动剂,可激活PPARγ,其EC50约为罗格列酮的EC50,对RIE细胞无影响。 了解更多
  33. Alexidine dihydrochloride

    Catalog No. A15382
    Quick View
    PTPMT1 抑制剂
    Alexidine dihydrochloride是烷基双(双胍)防腐剂,已用于漱口水中以消除形成斑块的微生物。 了解更多
  34. Bavisant dihydrochloride

    Catalog No. A15015
    Quick View
    H3 receptor 拮抗剂
    Bavisant dihydrochloride是一种人类H3受体的高选择性,口服活性拮抗剂。 了解更多
  35. GGACK Dihydrochloride

    Catalog No. A16057
    Quick View
    Urokinase 抑制剂
    GGACK Dihydrochloride是尿激酶(uPA(ICkin <1 ?M),凝血因子VIIa,凝血因子IXa,凝血因子Xa和胰蛋白酶的有效且不可逆的抑制剂。 了解更多
  36. DBM 1285 dihydrochloride

    Catalog No. A16058
    Quick View
    p38 MAPK 抑制剂
    DBM 1285 dihydrochloride是p38 MAPK抑制剂。在巨噬细胞和体内抑制p38磷酸化和LPS诱导的TNF-α产生。 了解更多
  37. Mibefradil dihydrochloride

    Catalog No. A12482
    Quick View
    Calcium channel blocker
    Mibefradil dihydrochloride是钙通道阻滞剂,对T型Ca2+通道具有中等选择性,对T型和L型通道的IC50值分别为2.7 uM和18.6 uM。 了解更多
  38. Cefepime Dihydrochloride Monohydrate

    Catalog No. A17272
    Quick View
    Cefepime Dihydrochloride Monohydrate is a broad-spectrum cephalosporin with enhanced coverage against Gram-positive and Gram-negative bacteria. 了解更多
  39. Minaprine dihydrochloride

    Catalog No. A17722
    Quick View
    MAO-A inhibitor
    Minaprine is a reversible inhibitor of MAO-A; weakly inhibit acetylcholinesterase; an antidepressant for treatment of depression. 了解更多
  40. Y-33075 dihydrochloride

    Catalog No. A11611
    Quick View
    ROCK inhibitor
    Y-33075 dihydrochloride is a selective ROCK inhibitor with an IC50 of 3.6 nM. 了解更多
  41. Dimebon 2HCl

    Catalog No. A10312
    Quick View
    Neuroprotectant
    Dimebon dihydrochloride是一种非选择性的抗组胺药,具有增强认知能力。 了解更多
  42. GYKI-52466 dihydrochloride

    Catalog No. A10444
    Quick View
    AMPA and Kainate 拮抗剂
    GYKI-52466 dihydrochloride是选择性非竞争性AMPA受体拮抗剂(对于AMPA、红藻氨酸和AMPA诱导的反应,IC50值分别为10-20、~ 450和> > 50 μM)。 了解更多
  43. SR 3677 dihydrochloride

    Catalog No. A12674
    Quick View
    ROCK 抑制剂
    SR 3677 dihydrochloride是一种有效的选择性Rho激酶抑制剂(ROCK-II和ROCK-I的IC50值分别为3和56 nM)。 了解更多
  44. E-4031 dihydrochloride

    Catalog No. A12857
    Quick View
    K+ channel blocker?
    E-4031 dihydrochloride是KV11.1(hERG)通道的选择性阻滞剂;禁止快速延迟整流器K+电流(IKr)。 了解更多
  45. 1400W Dihydrochloride

    Catalog No. A13583
    Quick View
    INOS 抑制剂
    1400W Dihydrochloride是一种缓慢,紧密结合,有效和高度选择性的诱导型一氧化氮合酶抑制剂(Kd = 7 nM)。对nNOS和eNOS具有选择性(Ki值分别为2和50μM)。细胞可渗透并在体内具有活性。 了解更多
  46. TPT-260 (Dihydrochloride)

    Catalog No. A13966
    Quick View
    TPT-260是噻吩硫脲衍生物。 了解更多
  47. HA-1077 dihydrochloride

    Catalog No. A13785
    Quick View
    ROCK 抑制剂
    HA-1077 dihydrochloride通过充当细胞内Ca2+拮抗剂来抑制血管平滑肌收缩。 了解更多
  48. cis-(Z)-Flupentixol dihydrochloride

    Catalog No. A12347
    Quick View
    Dopamine receptor 拮抗剂
    cis-(Z)-Flupentixol dihydrochloride是多巴胺受体拮抗剂、抗精神病药物、抗精神病药物。 了解更多
  49. Dexpramipexole dihydrochloride

    Catalog No. A15066
    Quick View
    dopamine 激动剂
    Dexpramipexole dihydrochloride是一种神经保护剂和弱非麦角灵多巴胺激动剂。 了解更多
  50. AT7867 2HCl

    Catalog No. A15006
    Quick View
    Akt 抑制剂
    AT7867 dihydrochloride是一种有效的ATP竞争性Akt1/2/3和p70S6K/PKA抑制剂,IC50分别为32 nM/17 nM/47 nM和85 nM/20 nM,在AGC激酶家族之外几乎没有活性。 了解更多

产品 1 到 50 共 116个

每页
页面:
  1. 1
  2. 2
  3. 3

设置升序顺序
Rewards