“abl”的搜索结果

10 个项目

每页

设置升序顺序
    • 最新产品

    KL1333

    Catalog No. A17234
    Quick View
    NAD+ Modulator
    KL1333 is an orally available, small organic molecule that reacts with NAD(P)H:quinone oxidoreductase 1 (NQO1) as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation. KL-1333 Improves Energy Metabolism and Mitochondrial Dysfunction in MELAS Fibroblasts. 了解更多
    • 最新产品

    PUN30119

    Catalog No. A17232
    Quick View
    PUN30119, also known as Imidazole ketone erastin (IKE), is a potent, metabolically stable inhibitor of system xc- and inducer of ferroptosis potentially suitable for in vivo applications. 了解更多
  1. Lasofoxifene Tartrate

    Catalog No. A18097
    Quick View
    selective Estrogen receptor modulator
    Lasofoxifene tartrate is a third-generation selective estrogen receptor modulator. 了解更多
  2. PZ-2891

    Catalog No. A18880
    Quick View
    PANK modulator
    PZ-2891 is an orally bioavailable, brain penetrant pantothenate kinase (PANK) modulator. PZ-2891 act as an orthosteric inhibitor at high concentrations and an allosteric activator at lower sub-saturating concentrations. PZ-2891 inhibits human pantothenate kinases PANK1β, PANK2, and PANK3 with IC50s of 40.2 nM, 0.7 nM and 1.3 nM, respectively. 了解更多
  3. BNC375

    Catalog No. A18503
    Quick View
    α7 nAChR Modulator
    BNC375 is a Potent, Selective, and Orally Available Type I Positive Allosteric Modulator of α7 nAChRs. 了解更多
  4. E6130

    Catalog No. A20056
    Quick View
    CX3CR1 modulator
    E6130 is an orally available and highly selective CX3CR1 modulator, that may be effective for treatment of inflammatory bowel disease. 了解更多
  5. MA-0204

    Catalog No. A19031
    Quick View
    PPARδ modulator
    MA-0204 is a potent, highly selective and orally available peroxisome proliferator activated receptor δ (PPARδ) modulator with EC50s of 0.4 nM, 7.9 nM and 10 nM for human, mouse and rat PPARδ, respectively. Potential treatment for Duchene Muscular Dystrophy (DMD). 了解更多
  6. GNE 0723

    Catalog No. A12757
    Quick View
    NMDAR modulator
    GNE 0723 is a brain permeable positive allosteric modulator of NMDAR, with an EC50 of 21 nM for GluN2A, 7.4 and 6.2 μM for GluN2C and GluN2D, respectively. 了解更多
  7. RAD140

    Catalog No. A21205
    Quick View
    androgen receptor modulator
    RAD140 is a potent, orally bioavailable, nonsteroidal selective androgen receptor modulator (SARM). 了解更多
  8. Basimglurant

    Catalog No. A21225
    Quick View
    mGlu5 negative allosteric modulator
    Basimglurant (RG7090) is a potent, selective and orally available mGlu5 negative allosteric modulator with a Kd of 1.1 nM. 了解更多

10 个项目

每页

设置升序顺序
Rewards