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￥ 0.00 “sb269970 hcl”的搜索结果
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Dorzolamide HCL
Catalog No. A10333 carbonic anhydrase 抑制剂Dorzolamide HCl是一种碳酸酐酶抑制剂。它是一种抗青光眼剂，以滴眼剂的形式局部使用。盐酸度尔佐胺用于降低开角型青光眼和高眼压患者的眼内压升高。 了解更多 -
Fasudil HCl (HA-1077)
Catalog No. A10381 ROCK 抑制剂Fasudil HCl (HA-1077)是一种环状核苷酸依赖性蛋白激酶抑制剂和Rho相关激酶抑制剂（IC50 = 10.7μM）。 了解更多 -
BMS-1166 hydrochloride
Catalog No. A21481 PD-1/PD-L1 interaction inhibitorBMS-1166 hydrochloride is a potent PD-1/PD-L1 interaction inhibitor with an IC50 of 1.4 nM. BMS-1166 antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation. 了解更多 -
CSRM617 Hydrochloride
Catalog No. A18438 OC2 inhibitorCSRM617 Hydrochloride is an inhibitor of the transcription factor ONECUT2 (OC2), thereby suppressing metastasis in mice. 了解更多 -
Molindone hydrochloride
Catalog No. A17647 MAO inhibitorMolindone HCl is a D2 dopamine receptor antagonist. It also acts as a MAO inhibitor. 了解更多 -
Proadifen HCl
Catalog No. A17386 Cytochrome P450 inhibitorProadifen hydrochloride is a Cytochrome P450 inhibitor (IC50 = 19μM). 了解更多 -
T-3775440 hydrochloride
Catalog No. A18340 LSD1 inhibitorT-3775440 (hydrochloride) is an irreversible lysine-specific histone demethylase (LSD1) inhibitor with an IC50 value of 2.1 nM. 了解更多 -
Tacrine HCl Hydrate
Catalog No. A16970 AChE and BChE 抑制剂Tacrine hydrochloride hydrate是乙酰（AChE）和丁酰胆碱酯酶（BChE）的抑制剂，IC50分别为31 nM和25.6 nM。 了解更多 -
Pazopanib HCl (GW786034)
Catalog No. A10699 VEGFR/PDGFR/FGFR 抑制剂Pazopanib HCl (GW786034)是VEGFR-1，VEGFR-2，VEGFR-3，PDGFR-a/β和c-kit的有效且选择性的多靶点酪氨酸激酶抑制剂，可阻止肿瘤生长并抑制血管生成。 了解更多 -
Irinotecan HCl Trihydrate (Campto)
Catalog No. A10479 Topoisomerase 抑制剂Irinotecan (CPT 11)是喜树碱家族的一种化合物，是参与细胞DNA复制和转录的拓扑异构酶1的抑制剂。 了解更多 -
Lexibulin dihydrochloride
Catalog No. A21774 tubulin polymerisation inhibitorLexibulin 2Hcl (CYT-997 2Hcl) is a potent tubulin polymerisation inhibitor with IC50 of 10-100 nM in cancer cell lines; with potent cytotoxic and vascular disrupting activity in vitro and in vivo. 了解更多 -
Azacosterol
Catalog No. A13295 -
K-7174 2HCl
Catalog No. A15446 Cell adhesion 抑制剂K-7174 dihydrochloride是一种新型的细胞粘附抑制剂；抑制由IL-1beta或TNF-alpha诱导的血管细胞粘附分子1（VCAM-1）的表达。 了解更多 -
KX2-391 2HCl
Catalog No. A11471 Src 抑制剂Tirbanibulin dihydrochloride是首个靶向Src肽底物位点的临床Src抑制剂(拟肽类),在癌细胞系中GI50为9-60 nM。 了解更多 -
AT7867 2HCl
Catalog No. A15006 Akt 抑制剂AT7867 dihydrochloride是一种有效的ATP竞争性Akt1/2/3和p70S6K/PKA抑制剂，IC50分别为32 nM/17 nM/47 nM和85 nM/20 nM，在AGC激酶家族之外几乎没有活性。 了解更多 -
Glycyl-H 1152 2HCl
Catalog No. A13659 ROCK 抑制剂Glycyl-H 1152 2HCl是一种选择性有效的ROCK抑制剂（ROCKII，Aurora A，CAMKII，PKG，PKA和PKC的IC50值分别为0.0118、2.35、2.57、3.26，> 10和> 10 uM。） 了解更多 -
Dorsomorphin 2HCl
Catalog No. A13720 BMP 抑制剂Dorsomorphin 2HCl (BML-275)是BMP信号传导的选择性小分子抑制剂，可促进胚胎干细胞的心肌发生。Dorsomorphin通过抑制骨形态发生蛋白信号转导逆转乳腺癌起始细胞的间质表型。 了解更多 -
Puromycin 2HCl
Catalog No. A14268 -
TAS 103 2HCl
Catalog No. A14141 -
GBR-12935 2HCl
Catalog No. A11937 -
BMS-790052 2HCl
Catalog No. A11336 -
Vanoxerine 2HCl (GBR-12909)
Catalog No. A10725 dopamine re-uptake 抑制剂Vanoxerine 2HCl (GBR-12909)是哌嗪衍生物，是一种有效的、选择性的多巴胺摄取（dopamine uptake）抑制剂。 了解更多 -
Vatalanib (PTK787) 2HCl
Catalog No. A10967 VEGFR 抑制剂Vatalanib (PTK787) 2HCl是一种小分子蛋白激酶抑制剂，可抑制抑制所有已知VEGF受体以及血小板衍生的生长因子受体β和c-kit的血管生成，但对VEGFR-2的选择性最高。 了解更多 -
Y-27632 2HCl
Catalog No. A11001 ROCK 抑制剂Y-27632是一种Rho相关的线圈激酶（ROCK）抑制剂，可提高人类胚胎干细胞（hESCs）的克隆效率。比对其他激酶包括PKC，cAMP依赖性蛋白激酶，MLCK和PAK的作用强200多倍。 了解更多 -
Nefazodone hydrochloride
Catalog No. A17622 5-HT2 receptors inhibitorNefazodone HCl is an inhibitor of 5-HT2 receptors, SERT, NET, and hERG K+ channels used to treat mood disorders. It decreases immobility time in the forced swim test. 了解更多 -
Tacrine HCl
Catalog No. A17374 AChE & butyrylcholinesterase inhibitorTacrine is a derivative of aminoacridine that functions as an inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (IC50s = 31 and 26.5 nM, respectively). 了解更多 -
IPI-504 (Retaspimycin HCl)
Catalog No. A11269 -
Nepicastat HCl
Catalog No. A11172 -
Benazepril HCl
Catalog No. A10123 -
PD153035 (HCl salt)
Catalog No. A10702 -
Piperidolate hydrochloride
Catalog No. A18144 antimuscarinicPiperidolate hydrochloride is an antimuscarinic, Also a potential inhibitor of human glutathione transferase P1-1. 了解更多 -
Promazine hydrochloride
Catalog No. A17638 D2DR inhibitorPromazine Hydrochloride is a phenothiazine compound and D2DR inhibitor. Promazine Hydrochloride has been employed in studies investigating dopamine-stimulated glycosylation of brain proteins in vitro. It has actions similar to chlorpromazine but with less antipsychotic activity. 了解更多 -
AX-024 hydrochloride
Catalog No. A18332 TNF receptor inhibitorAX-024 is an orally available inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation (IC50 value 1 nM). Inhibiting an immediate TCR signal has promise for treating a broad spectrum of human T cell-mediated autoimmune and inflammatory diseases. 了解更多 -
Pargyline hydrochloride
Catalog No. A17288 MAO inhibitorPargyline hydrochloride is an irreversible inhibitor of monoamine oxidase (MAO) that is used clinically to treat moderate hypertension. 了解更多 -
Pitofenone Hydrochloride
Catalog No. A17053 -
AN3365
Catalog No. A16329 -
TGR-1202 hydrochloride (Umbralisib HCl)
Catalog No. A16278 PI3Kδ 抑制剂TGR-1202 hydrochloride是一种口服的下一代PI3Kδ抑制剂，在基于酶和细胞的测定中抑制PI3Kδ活性，IC50和EC50值分别为22.2和24.3 nM。 了解更多 -
BI 1467335 (PXS 4728A)
Catalog No. A16082 SSAO/VAP-1 抑制剂BI 1467335 (PXS 4728A)是一种非常有效和高度选择性的化合物，正在开发中，用于治疗心脏代谢疾病，例如肝脏相关疾病非酒精性脂肪性肝炎（NASH）。 了解更多 -
MRT68921
Catalog No. A15880 -
Asenapine HCl
Catalog No. A15002 adrenergic receptor/5-HT receptor 抑制剂Asenapine hydrochloride抑制肾上腺素能受体（α1，α2A，α2B，α2C）的Ki为0.25-1.2 nM，还抑制5-HT受体（1A，1B，2A，2B，2C，5A，6、7），Ki为0.03- 4.0 nM。 了解更多 -
Vandetanib HCl
Catalog No. A15271 -
TG 100801 HCl
Catalog No. A15261 VEGFr2 抑制剂TG 100801 HCl是TG 100572（HY-10184）的前药，TG 100572是一种多靶点激酶抑制剂，可抑制选择性生长因子受体酪氨酸激酶和Src家族激酶，IC50值为2/7/2/1/0.5 nM或VEGFR1/VEGFR2/FGFR1/Src/Fyn kianse分别。 了解更多 -
TG 100572 HCl
Catalog No. A15260 VEGFR2/Src kinase 抑制剂TG 100572 HCl是一种多靶点激酶抑制剂，可抑制选择性生长因子受体酪氨酸激酶和Src家族激酶，分别对VEGFR1/VEGFR2/FGFR1/Src/Fyn kianse的IC50值为2/7/2/1/0.5 nM。 了解更多 -
SB-505124 HCl
Catalog No. A15232 -
CC-401 hydrochloride
Catalog No. A15037 -
Nisoxetine hydrochloride
Catalog No. A13418 Noradrenalin re-uptake 抑制剂Nisoxetine hydrochloride是去甲肾上腺素转运蛋白的选择性强抑制剂，对一系列其他神经递质受体几乎没有或没有亲和力。Nisoxetine hydrochloride是SLC6A2的抑制剂。 了解更多
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