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AFP464

Catalog No. A20978
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HIF-1?? inhibitor

AFP464, is an active HIF-1α inhibitor with an IC50 of 0.25 μM, also is a potent aryl hydrocarbon receptor (AhR) activator. 了解更多

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ZINC13466751

Catalog No. A12522
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HIF-1α/von Hippel-Lindau interaction inhibitor

ZINC13466751 is a potent inhibitor of HIF-1α/von Hippel-Lindau interaction with an IC50 of 2.0 ?M. 了解更多

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EL-102

Catalog No. A20925
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HIF1α inhibitor

EL102 is a inhibitor of HIF1α , Which can inhibit tubulin polymerisation and decreased microtubule stability. 了解更多

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(Rac)-PT2399

Catalog No. A21376
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HIF-2α inhibitor

(Rac)-PT2399 (Compound 10e), the racemate of PT2399, acts as a potent and specific hypoxia-inducible factor 2a (HIF-2α) inhibitor with an IC50 of 0.01 μM. 了解更多

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PT-2385

Catalog No. A21561
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HIF-2α inhibitor

PT-2385 is a selective HIF-2α inhibitor with a Ki of less than 50 nM. 了解更多

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PX-478 HCl

Catalog No. A14319
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HIF-1alpha 抑制剂

PX-478 HCl是HIF-1alpha抑制剂，也是具有潜在抗肿瘤活性小分子。PX-478对已建立的人类肿瘤异种移植物具有出色的活性，可提供具有HIF-1水平正相关的延长的生长延迟的肿瘤消退。PX-478是高度水溶性的分子，具有良好的i.v.，i.p.和p.o.抗肿瘤活性。了解更多

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PT2977

Catalog No. A18465
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HIF-2alpha inhibitor

PT2977 is HIF-2alpha inhibitor with an IC50 of 9 nM. 了解更多

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