“alpha ergocryptine”的搜索结果
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HIF-2alpha inhibitor
PT2977 is HIF-2alpha inhibitor with an IC50 of 9 nM.
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HIF-1alpha 抑制剂
PX-478 HCl是HIF-1alpha抑制剂,也是具有潜在抗肿瘤活性小分子。PX-478对已建立的人类肿瘤异种移植物具有出色的活性,可提供具有HIF-1水平正相关的延长的生长延迟的肿瘤消退。PX-478是高度水溶性的分子,具有良好的i.v.,i.p.和p.o.抗肿瘤活性。
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HIF-2α inhibitor
PT-2385 is a selective HIF-2α inhibitor with a Ki of less than 50 nM.
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HIF-2α inhibitor
(Rac)-PT2399 (Compound 10e), the racemate of PT2399, acts as a potent and specific hypoxia-inducible factor 2a (HIF-2α) inhibitor with an IC50 of 0.01 μM.
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HIF1α inhibitor
EL102 is a inhibitor of HIF1α , Which can inhibit tubulin polymerisation and decreased microtubule stability.
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HIF-1α/von Hippel-Lindau interaction inhibitor
ZINC13466751 is a potent inhibitor of HIF-1α/von Hippel-Lindau interaction with an IC50 of 2.0 ?M.
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Syk/PI3K inhibitor
SRX3207 is an orally active and first-in-class dual Syk/PI3K inhibitor, with IC50 values of 10.7 nM and 861 nM for Syk and PI3Kα, respectively. SRX3207 relieves tumor immunosuppression.
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HIF-1?? inhibitor
AFP464, is an active HIF-1α inhibitor with an IC50 of 0.25 μM, also is a potent aryl hydrocarbon receptor (AhR) activator.
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