你的浏览器似乎禁用了 JavaScript。
您必须在浏览器中启用JavaScript才能使用本网站的功能。

微信关注
申请试用装

主页 /
搜索结果：“glucagon receptor”

“glucagon receptor”的搜索结果

Quick View
MK 3207 HCl

Catalog No. A10598
Quick View

添加到收藏
CGRP Receptor 拮抗剂

MK 3207 hydrochloride是一种有效的CGRP受体拮抗剂，IC50为0.12 nM。了解更多

Product Citations (1)

Bulk Inquiry
- Marlene Dallmayer, .et al. Targeting the CALCB/RAMP1-axis inhibits growth of Ewing sarcoma, bioRxiv, 2018, 2018
Quick View
Zibotentan (ZD4054)

Catalog No. A11006
Quick View

添加到收藏
ETA-receptor 拮抗剂

Zibotentan (ZD4054)是一种有效且特异性的ETA受体（内皮素A受体）拮抗剂（IC50 = 21 nM），对ETB没有抑制活性。了解更多

Product Citations (1)

Bulk Inquiry
- Tony Ngo, .et al. Orphan receptor ligand discovery by pickpocketing pharmacological neighbors, Nat Chem Biol, 2017, Feb; 13(2): 235-242 PMID: 27992882
Quick View
Ramelteon (TAK-375)

Catalog No. A10777
Quick View

添加到收藏
MT1/MT2-Receptor 激动剂

Ramelteon (TAK-375)是melatonin受体激动剂，对褪黑激素MT1（IC50 = 28.5±8.55 pM）和MT2（20.1±9.25 pM）受体均具有高亲和力，并且相对于MT3受体具有选择性。了解更多

Bulk Inquiry Free Sample
Quick View
Puerarin (Kakonein)

Catalog No. A10759
Quick View

添加到收藏
5-HT2C receptor 拮抗剂

Puerarin (Kakonein)是几种已知的异黄酮之一。Puerarin是5-HT2C受体和苯二氮卓类拮抗剂。Puerarin正在研究作为一种自微乳化药物递送系统。了解更多

Product Citations (3)

Bulk Inquiry
- Takashi Azuma, .et al. Removal of pharmaceuticals in water by introduction of ozonated microbubbles, SEP PURIF TECHNOL, 2019, Apr; 212: 483-489
- Azuma T, .et al. Distribution of six anticancer drugs and a variety of other pharmaceuticals, and their sorption onto sediments, in an urban Japanese river, Environ Sci Pollut Res Int, 2017, Aug;24(23):19021-19030 PMID: 28660504
- Azuma T, .et al. Detection of pharmaceuticals and phytochemicals together with their metabolites in hospital effluents in Japan, and their contribution to sewage treatment plant influents, Sci Total Environ, 2016, Apr 1;548-549:189-197 PMID: 26802347
Quick View
Naftopidil 2HCl

Catalog No. A10619
Quick View

添加到收藏
5-HT1A and α1-adrenergic receptor 拮抗剂

Naftopidil 2HCl是选择性5-HT1A和α1-肾上腺素能受体拮抗剂，IC50分别为0.1μM和0.2μM。了解更多

Bulk Inquiry
Quick View
PNU-120596

Catalog No. A11203
Quick View

添加到收藏
Nicotinic (α7) Receptor Modulator

PNU-120596是α7神经元烟碱型乙酰胆碱受体的正变构调节剂。了解更多

Bulk Inquiry Free Sample
Quick View
BRL-15572 dihydrochloride

Catalog No. A11178
添加到收藏
5-HT1D receptor 拮抗剂

BRL-15572是一种选择性的h5-HT1D拮抗剂，相对于h5-HT1B表现出60倍的选择性，对一系列其他受体类型的亲和力很小或没有亲和力。了解更多

Bulk Inquiry
Quick View
5-hydroxymethyl tolterodine (PNU 200577)

Catalog No. A11166
Quick View

添加到收藏
muscarinic receptor 拮抗剂

5-hydroxymethyl tolterodine (PNU 200577)是托特罗定的代谢产物，tolterodine是一种用于治疗尿失禁的毒蕈碱受体拮抗剂。了解更多

Bulk Inquiry Free Sample
Quick View
Aprepitant (MK-0869)

Catalog No. A10083
Quick View

添加到收藏
neurokinin-1 receptor 拮抗剂

Aprepitant (MK-0869)被归类为NK1拮抗剂。已经显示，阿瑞匹坦通过阻止P物质降落在大脑神经元受体上，从而抑制细胞毒性化疗药物引起的急性呕吐和延迟呕吐。还显示出它能增加5-HT3受体拮抗剂恩丹西酮和皮质类固醇地塞米松的活性，它们也可用于预防化学疗法引起的恶心和呕吐。了解更多

Product Citations (1)

Bulk Inquiry Free Sample
- Kodji X, .et al. Sensory nerves mediate spontaneous behaviors in addition to inflammation in a murine model of psoriasis, FASEB J, 2018, Sep 11:fj201800395RR PMID: 30204499
Quick View
Cyproterone acetate

Catalog No. A11409
Quick View

添加到收藏
Androgen Receptor 拮抗剂

Cyproterone acetate是17-羟孕酮的合成衍生物，可作为雄激素受体拮抗剂以及具有弱孕激素和糖皮质激素活性的弱孕激素受体激动剂。了解更多

Bulk Inquiry Free Sample
Quick View
Bexarotene (LGD1069)

Catalog No. A11094
Quick View

添加到收藏
Retinoid X Receptor Ligand

Bexarotene (LGD1069)是一种高度选择性的类维生素A X受体（RXR）激动剂。了解更多

Bulk Inquiry Free Sample
Quick View
ADL5859 HCl

Catalog No. A11072
Quick View

添加到收藏
Opioid Receptor 激动剂

ADL5859 HCl是高效的选择性δ阿片受体激动剂，Ki值为0.84 nM，ED50值为20 nM。了解更多

Bulk Inquiry Free Sample
Quick View
Andarine (GTX-007)

Catalog No. A10076
Quick View

添加到收藏
Androgen Receptor 激动剂

Andarine (GTX-007)是研究性的选择性雄激素受体调节剂（SARM）。了解更多

Bulk Inquiry Free Sample
Quick View
Ki16425

Catalog No. A10501
Quick View

添加到收藏
LPA Receptor 拮抗剂

ki16425是对LPA1和LPA3具有选择性的LPA受体拮抗剂，对人LPA1、LPA2和LPA3受体分别显示Ki值为0.34、6.5和0.93 μM。了解更多

Product Citations (5)

Bulk Inquiry Free Sample
- Maria F Fernandes, .et al. Glucagon-like Peptide-1 Secretion Is Inhibited by Lysophosphatidic Acid, Int J Mol Sci, 2022, Apr 9;23(8):4163 PMID: 35456981
- Rieko Suenaga, .et al. Lateral access mechanism of LPA receptor probed by molecular dynamics simulation, PLoS One, 2022, Feb 3;17(2):e0263296 PMID: 35113924
- Inoue A, .et al. Illuminating G-Protein-Coupling Selectivity of GPCRs, Cell, 2019, Jun 13;177(7):1933-1947 PMID: 31160049
- Taniguchi R, .et al. Structural insights into ligand recognition by the lysophosphatidic acid receptor LPA6, Nature, 2017, Aug 17;548(7667):356-360 PMID: 28792932
- T. HASHIMOTO, .et al. Generalized pruritus in primary sclerosing cholangitis: implications of histamine release by lysophosphatidic acid., Br J Dermatol., 2015, Nov;173(5):1334-6 PMID: 26122943
Quick View
Hexestrol

Catalog No. A10451
Quick View

添加到收藏
Estrogen/progestogen Receptor 激动剂

Hexestrol是一种致癌的合成雌激素，可抑制微管聚合和带状结构的形成。它是脂质过氧化的抑制剂。了解更多

Bulk Inquiry Free Sample
Quick View
Agomelatine

Catalog No. A10048
Quick View

添加到收藏
5-HT Receptor 拮抗剂

Agomelatine是一种褪黑素激动剂（MT1和MT2受体）和5-HT2C拮抗剂。了解更多

Bulk Inquiry
Quick View
Amisulpride

Catalog No. A10067
Quick View

添加到收藏
Dopamine Receptor 拮抗剂

Amisulpride是一种非典型抗精神病药，用于治疗精神分裂症的精神病和双相情感障碍的躁狂发作。了解更多

Bulk Inquiry
Quick View
Bicalutamide (Casodex)

Catalog No. A10142
Quick View

添加到收藏
Androgen Receptor 拮抗剂

Bicalutamide (Casodex)是一种口服非甾体抗雄激素，用于治疗前列腺癌和多毛症。了解更多

Product Citations (5)

Bulk Inquiry Free Sample
- Mi Chen, .et al. TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation, EMBO Rep, 2022, Aug 3;23(8):e53468 PMID: 35785414
- Takashi Azuma, .et al. Removal of pharmaceuticals in water by introduction of ozonated microbubbles, SEP PURIF TECHNOL, 2019, Apr; 212: 483-489
- Anowara Khatun, .et al. Transcriptional Repression and Protein Degradation of the Ca2+-Activated K+ Channel KCa1.1 by Androgen Receptor Inhibition in Human Breast Cancer Cells, Front Physiol, 2018, 9: 312 PMID: 29713287
- Azuma T, .et al. Distribution of six anticancer drugs and a variety of other pharmaceuticals, and their sorption onto sediments, in an urban Japanese river, Environ Sci Pollut Res Int, 2017, Aug;24(23):19021-19030 PMID: 28660504
- Azuma T, .et al. Detection of pharmaceuticals and phytochemicals together with their metabolites in hospital effluents in Japan, and their contribution to sewage treatment plant influents, Sci Total Environ, 2016, Apr 1;548-549:189-197 PMID: 26802347
Quick View
Tianeptine sodium

Catalog No. A10931
Quick View

添加到收藏
5-HT Receptor 激动剂

Tianeptine钠是体内和体外的选择性5-羟色胺再摄取促进剂（SSRE）。了解更多

Bulk Inquiry
Quick View
Mosapride citrate

Catalog No. A10607
Quick View

添加到收藏
5-HT4-receptor 激动剂

Mosapride citrate起5-HT4受体激动剂和5-HT3受体拮抗剂的作用。了解更多

Bulk Inquiry Free Sample
Quick View
FTY720 (Fingolimod)

Catalog No. A10408
Quick View

添加到收藏
S1P Receptor 拮抗剂

FTY720 (Fingolimod)是ISP-1(肉豆蔻酸)的衍生物，ISP-1是中国草药Iscaria sinclarii的真菌代谢物，也是鞘氨醇的结构类似物。了解更多

Product Citations (5)

Bulk Inquiry
- Tina Sepasi, .et al. Targeted gene delivery to the brain using CDX-modified chitosan nanoparticles, BioImpacts, 2022, 28 May
- Zengzi Zhou, .et al. Effects of immunomodulatory drug Fingolimod (FTY720) on Chlamydia dissemination and pathogenesis, Infect Immun, 2020, Oct 19;88(11):e00281-20 PMID: 32868341
- Mayu Idehara, .et al. Inulooligosaccharides in Atractylodis lanceae rhizoma and Atractylodis rhizoma of hochuekkito formula are essential for regulation of the pulmonary immune system of immuno-compromised mice, Traditional & Kampo Medicine, 2020, 22 July
- Luwa Yuan, .et al. 14-3-3 signal adaptor and scaffold proteins mediate GPCR trafficking, Sci Rep, 2019, 9:11156 PMID: 31371790
- Sakai Y, .et al. Peyer's patch-immunomodulating glucans from sugar cane enhance protective immunity through stimulation of the hemopoietic system, Int J Biol Macromol, 2018, Nov 22;124:505-514 PMID: 30471397

联系我们

Not your Region? View all Distributors

ADOOQ 产品质量保证

Guaranteed product quality, 365 days Unconditional Return & Replacement

We promise all products to perform as described.