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31 个项目
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Cenicriviroc Mesylate
Catalog No. A17028 CCR2/5 receptors 抑制剂Cenicriviroc(TAK-652,TBR-652)是CCR2和CCR5受体的抑制剂，可使其充当防止病毒进入人细胞的进入抑制剂 了解更多 -
LY 255283
Catalog No. A13090 -
Toll-Like Receptor 7 Ligand II
Catalog No. A12683 TLR7 LigandToll-Like Receptor 7 Ligand II是一种细胞可渗透的羟基腺嘌呤化合物，可作为强效且高度特异性的TLR7（toll样受体7）激动剂，对TLR2/3/5/8/9没有任何可检测的活性。它在刺激体外培养物中产生TLR7依赖性细胞因子方面比R848效力高10倍。 了解更多 -
Toll-like receptor modulator
Catalog No. A15264 Toll-like receptor modulator是一类在先天免疫系统中起关键作用的蛋白质。是一类在先天免疫系统中起关键作用的蛋白质。 了解更多 -
IRAK inhibitor 3
Catalog No. A11457 IL-1 receptor-associated kinase (IRAK) kinase modulatorIRAK inhibitor 3 is an interleukin-1 (IL-I) receptor-associated kinase (IRAK) kinase modulator extracted from patent WO2008030579 A2. 了解更多 -
Fexofenadine HCl
Catalog No. A11859 COX 抑制剂/histamine H1 receptor 激动剂Fexofenadine Hydrochloride是一种抗组胺药，可抑制Cox-1，Cox-2，并且是组胺H1受体激动剂，IC50为246 nM。 了解更多 -
AMG 487 S-enantiomer
Catalog No. A21874 CXCR3 antagonistAMG 487 S-enantiomer is the S enantiomer of AMG 487. AMG 487 is an antagonist of the chemokine receptor CXCR3. 了解更多 -
TLR7/8 agonist 1 dihydrochloride
Catalog No. A21700 TLR7/8 agonistTLR7/8 agonist 1 dihydrochloride is a toll-like receptor (TLR7)/TLR8 dual-agonistic imidazoquinoline. 了解更多 -
SCH 546738
Catalog No. A21554 CXCR3 antagonistSCH 546738 is a potent, orally active and non-competitive CXCR3 antagonist, the affinity constant (Ki) of SCH 546738 binding to human CXCR3 receptor is determined to be 0.4 nM in multiple experiments. 了解更多 -
Resatorvid
Catalog No. A11543 TLR4 inhibitorResatorvid (TAK-242) is a selective Toll-like receptor 4 (TLR4) inhibitor and plays pivotal role in various inflammatory diseases. 了解更多 -
Kynurenic acid sodium
Catalog No. A20000 GPR35/CXCR8 agonistKynurenic acid sodium, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid sodium is also an agonist of GPR35/CXCR8. 了解更多 -
GPR35 agonist 1
Catalog No. A12462 GPR35/CXCR8 agonistGPR35 agonist 1 (compound 50) is a potent and specific G protein-coupled receptor-35 (GPR35)/CXCR8 agonist with an EC50 of 5.8 nM, displays good druggability. 了解更多 -
GSK2239633A
Catalog No. A12175 CCR4 antagonistGSK2239633A is a CC-chemokine receptor 4 (CCR4) antagonist, which inhibits the binding of [125I]-TARC to human CCR4 with a pIC50 of 7.96????0.11. 了解更多 -
PF-4878691
Catalog No. A12233 TLR7 agonistPF-4878691 (3M-852A) is a potent, orally active, and selective Toll-like receptor 7 (TLR7) agonist modelled to dissociate its antiviral and inflammatory activities. 了解更多 -
MD2-TLR4-IN-1
Catalog No. A18452 MD2-TLR4 inhibitorMD2-TLR4-IN-1 (compound 22m) is an inhibitor of myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex, inhibiting lipopolysaccharides (LPS)-induced expression of tumor necrosis factor alpha (TNF-α) and interleukin-6 (IL-6) in macrophages with IC50 values of 0.89 μM and 0.53 μM, respectively. 了解更多 -
CCR4 antagonist 2
Catalog No. A18471 CCR4 拮抗剂CCR4 antagonist 2 (Compound 31) is a novel potent, orally bioavailable small molecule antagonists of CC chemokine receptor 4 (CCR4) that inhibits Treg trafficking into the Tumor Microenvironment without suppressing the number of Treg in healthy tissues. 了解更多 -
Kynurenic acid
Catalog No. A16581 GPR35/CXCR8 拮抗剂Kynurenic acid, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid is also an agonist of GPR35/CXCR8. 了解更多 -
PF-04634817
Catalog No. A18659 CCR2 /CCR5 dual 拮抗剂PF-04634817 is an orally administered CCR2 and CCR5 chemokine receptor antagonist, for the treatment of diabetic nephropathies and diabetic macular oedema. 了解更多 -
Montelukast
Catalog No. A17780 LTR antagonistMontelukast (trade name Singulair) is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. 了解更多 -
MK-571 sodium salt
Catalog No. A15983 CysLT1 receptor 拮抗剂MK-571 sodium salt是一种选择性的口服活性CysLT1受体拮抗剂。它阻断LTD4而不是LTC4与人和豚鼠肺膜的结合，Ki值分别为0.22 nM和2.1 nM。 了解更多 -
Reparixin L-lysine salt
Catalog No. A15219 CXCL8 receptor 抑制剂Reparixin L-lysine salt是CXCL8受体的抑制剂，也抑制CXCR1和CXCR2的活化，已显示在各种损伤模型中减弱了炎症反应。 了解更多 -
MK-0679 (Verlukast)
Catalog No. A11607
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