“ab fubinaca”的搜索结果

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  1. VP3.15 dihydrobromide

    Catalog No. A21789
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    PDE7/GSK3 inhibitor
    VP3.15 dihydrobromide is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively. 了解更多
  2. SKL2001

    Catalog No. A16707
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    Wnt/β-catenin agonist
    SKL2001 is an agonist of the Wnt/β-catenin pathway, with anti-cancer activity. SKL2001 stabilizes intracellular β-catenin via disruption of the Axin/β-catenin interaction. 了解更多
  3. U18666A

    Catalog No. A20195
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    cholesterol synthesis/Hedgehog inhibitor
    U18666A, a cell permeable drug, is a cholesterol synthesis and transport inhibitor. 了解更多
  4. VP3.15

    Catalog No. A18538
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    dual PDE7/GSK-3 inhibitor
    VP3.15 is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively. VP3.15 has neuroprotective and neuroreparative activities, thus as potential combined anti-inflammatory and pro-remyelinating therapies for multiple sclerosis (MS). 了解更多
  5. NGP-555

    Catalog No. A17051
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    γ-Secretase Modulator
    NGP-555是一种γ-分泌酶调节剂,具有选择性机制,可减少Abeta 42,同时提高较短的Abeta形式,例如Abeta 37和38。 了解更多
  6. Bikinin

    Catalog No. A15526
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    GSK-3 抑制剂
    Bikinin是植物GSK-3/Shaggy-like激酶的有效抑制剂。激活BR受体下游的BR信号传导。 了解更多
  7. MRK 560

    Catalog No. A15304
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    γ-secretase 抑制剂
    MRK 560是一种可用的γ-分泌酶抑制剂,能够显着减少大鼠脑和CSF中的Abeta肽,并证实该大鼠可用于评估γ-分泌酶抑制剂对中枢神经系统Abeta的作用(40)体内水平。 了解更多
  8. TBB

    Catalog No. A15257
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    CK2 抑制剂
    TBB是酪蛋白激酶2(CK2)的高选择性,ATP/GTP竞争性抑制剂,对大鼠肝脏和人重组CK2的IC50分别为0.9和1.6 uM。 了解更多
  9. BC2059

    Catalog No. A14381
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    beta-catenin inhibitor
    BC2059 is an orally bioavailable and potent beta-catenin inhibitor. 了解更多

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