“sb269970 hcl”的搜索结果

产品 51 到 99 共 99个

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  1. SB 399885 HCl

    Catalog No. A14102
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    5-HT6 拮抗剂
    SB 399885 hydrochloride是一种有效的,脑渗透剂和口服活性的SR-6拮抗剂。它对SR-6的选择性比其他血清素受体高200倍(对于人类重组,天然大鼠和天然人类SR-6受体,pKi值分别为9.11、8.81和9.02)。 了解更多
  2. MPEP HCl

    Catalog No. A13236
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    mGlu5 receptor 拮抗剂
    MPEP HCl是对mGlu5a受体亚型(IC50 = 36 nM)的有效,高度选择性的非竞争性拮抗剂,但在浓度高达30 uM的mGlu1b受体上无激动剂或拮抗剂活性。 了解更多
  3. SDZ 205-557 HCl

    Catalog No. A13766
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    5-HT4 Receptor 拮抗剂
    SDZ 205-557 HCl是一种有效的选择性5-HT4 5-羟色胺受体拮抗剂。 了解更多
  4. CP 945598 HCl (Otenabant HCl)

    Catalog No. A11942
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    CB1 拮抗剂
    CP 945598 HCl (Otenabant HCl)是一种有效且高度选择性的CB1拮抗剂。 了解更多
  5. Isoprenaline HCl

    Catalog No. A10484
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    β adrenoceptor 激动剂
    Isoprenaline HCl或isoproterenol是非选择性β肾上腺素能激动剂,在结构上类似于肾上腺素。 了解更多
  6. Buspirone HCl

    Catalog No. A15687
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    5HT(1A) receptor 激动剂
    Buspirone hydrochloride是一种具有5-D(2)多巴胺能作用的血清素能(5HT(1A)受体激动剂)抗焦虑药,用于焦虑症。 了解更多
  7. SKF38393 HCl

    Catalog No. A15839
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    Dopamine Receptor 激动剂?
    SKF38393 HCl是D1激动剂,IC50为110 nM。 了解更多
  8. Cyclobenzaprine HCl

    Catalog No. A14255
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    5-HT2 receptor 拮抗剂
    Cyclobenzaprine HCl是一种肌肉松弛剂,可阻止疼痛感。 了解更多
  9. Promethazine HCl

    Catalog No. A14248
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    Histamine H1 receptor 拮抗剂
    Promethazine HCl是一种有效的组胺H1受体拮抗剂。 了解更多
  10. Azelastine HCl (Allergodil)

    Catalog No. A10117
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    Azelastine HCl (Allergodil)是有效的第二代选择性组胺拮抗剂(组胺-H1-受体拮抗剂)。 了解更多
  11. Cyclizine 2HCl

    Catalog No. A16472
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    Histamine H1 receptor 拮抗剂
    Cyclizine 2HCl是具有组胺H1受体拮抗剂活性的哌嗪衍生物。 了解更多
  12. JP 1302 2HCl

    Catalog No. A13412
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    α2C 拮抗剂
    JP 1302 2HCl是一种强效和选择性α2C拮抗剂。 了解更多
  13. A 943931 2HCl

    Catalog No. A13442
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    Histamine H4 receptor 拮抗剂
    943931 2HCl是一种有效的选择性组胺H4受体拮抗剂(人和大鼠受体的pKi值分别为7.15和8.12)。 了解更多
  14. Cetirizine Dihydrochloride

    Catalog No. A10195
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    Cetirizine Dihydrochloride是第二代抗组胺药,是羟嗪的主要代谢产物,是用于治疗过敏,花粉症,血管性水肿和荨麻疹的消旋选择性H1受体反向激动剂。 了解更多
  15. GBR-12935 2HCl

    Catalog No. A11937
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    DAT and SLC6A2 抑制剂
    GBR-12935 dihydrochloride是一种有效的选择性多巴胺再摄取抑制剂。 了解更多
  16. B-HT 920 2HCl

    Catalog No. A11341
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    D2 receptor 激动剂
    B-HT 920 2HCl是一种多巴胺激动剂,已被提议用作抗帕金森病药物。它还具有α1肾上腺素能和α2肾上腺素能激动剂活性。 了解更多
  17. Pramipexole dihydrochloride monohyrate

    Catalog No. A10747
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    Dopamine Receptor 激动剂
    Pramipexole dihydrochloride monohyrate是非麦角灵类的多巴胺激动剂,适用于治疗早期帕金森氏病(PD)和不安腿综合征(RLS)。 了解更多
  18. Plerixafor 8HCl (DB06809)

    Catalog No. A10913
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    CXCR4 拮抗剂
    Plerixafor 8HCl (DB06809)是CXCR4趋化因子受体拮抗剂,作用于CXCR4和CXCL12介导调节的趋化性, IC50分别为44 nM和5.7 nM。 了解更多
  19. Vanoxerine 2HCl (GBR-12909)

    Catalog No. A10725
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    dopamine re-uptake 抑制剂
    Vanoxerine 2HCl (GBR-12909)是哌嗪衍生物,是一种有效的、选择性的多巴胺摄取(dopamine uptake)抑制剂。 了解更多
  20. Naftopidil 2HCl

    Catalog No. A10619
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    5-HT1A and α1-adrenergic receptor 拮抗剂
    Naftopidil 2HCl是选择性5-HT1A和α1-肾上腺素能受体拮抗剂,IC50分别为0.1μM和0.2μM。 了解更多
  21. MCOPPB 3HCl

    Catalog No. A10561
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    NOP receptor 激动剂
    MCOPPB 3HCl是一种用作伤害感受器受体的有效和选择性激动剂的化合物,pKi为10.07。 了解更多
  22. Ziprasidone hydrochloride

    Catalog No. A16790
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    5-HT (serotonin)/dopamine receptor antagonist
    Ziprasidone Hcl(CP-88059 Hcl) is a combined 5-HT (serotonin) and dopamine receptor antagonist which exhibits potent effects of antipsychotic activity. 了解更多
  23. Nefazodone hydrochloride

    Catalog No. A17622
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    5-HT2 receptors inhibitor
    Nefazodone HCl is an inhibitor of 5-HT2 receptors, SERT, NET, and hERG K+ channels used to treat mood disorders. It decreases immobility time in the forced swim test. 了解更多
  24. Melitracen hydrochloride

    Catalog No. A17494
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    dopamine D1/2 receptor antagonist
    Melitracen HCl ia potential dopamine D1/2 receptor antagonist used to treat depression. It is often co-administered with flupenthixol as a treatment for trigeminal neuralgia. It does not effect cardiovascular function. 了解更多
  25. CBiPES HCl

    Catalog No. A15811
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    mGlu2 receptor modulator
    CBiPES HCl是mGluR-2的选择性正变构调节剂,IC50值为98.2 nM。 了解更多
  26. Moxonidine Hydrochloride

    Catalog No. A13416
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    imidazoline receptor 1 激动剂
    Moxonidine Hydrochloride (BDF5895)是咪唑啉1型受体(I1-R)选择性激动剂,为降压剂。 了解更多
  27. Trazodone HCl

    Catalog No. A11703
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    Trazodone HCl 是一种抗抑郁药,属于5-羟色胺受体拮抗剂和再摄取抑制剂。 了解更多
  28. MK 3207 HCl

    Catalog No. A10598
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    CGRP Receptor 拮抗剂
    MK 3207 hydrochloride是一种有效的CGRP受体拮抗剂,IC50为0.12 nM。 了解更多
  29. Metoclopramide hydrochloride hydrate

    Catalog No. A18072
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    Dopamine D2 antagonist
    Metoclopramide hydrochloride hydrate is a dopamine D2 antagonist that is used as an antiemetic. 了解更多
  30. Metipranolol hydrochloride

    Catalog No. A18064
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    β-adrenergic receptor antagonist
    Metipranolol (hydrochloride) is a non-selective β-adrenergic receptor (β-AR) antagonist. Formulations containing metipranolol have been used in the treatment of elevated IOP in patients with ocular hypertension or glaucoma. 了解更多
  31. Moxisylyte hydrochloride

    Catalog No. A17725
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    alpha-adrenergic blocking agent
    Moxisylyte hydrochloride is an alpha-adrenergic blocking agent that is used in Raynaud's disease. It is also used locally in the eye to reverse the mydriasis caused by phenylephrine and other sympathomimetic agents. 了解更多
  32. Promazine hydrochloride

    Catalog No. A17638
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    D2DR inhibitor
    Promazine Hydrochloride is a phenothiazine compound and D2DR inhibitor. Promazine Hydrochloride has been employed in studies investigating dopamine-stimulated glycosylation of brain proteins in vitro. It has actions similar to chlorpromazine but with less antipsychotic activity. 了解更多
  33. SCH 23390 HCl

    Catalog No. A13066
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    D1/D5 receptor 拮抗剂
    SCH 23390 HCl是一种有效的多巴胺受体拮抗剂(D1和D5受体亚型的Ki值分别为0.2 nM和0.3 nM)。 了解更多
  34. Atrasentan HCl

    Catalog No. A15007
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    Endothelin 拮抗剂 receptor
    Atrasentan hydrochloride是一种开发用于治疗前列腺癌的内皮素拮抗剂受体(IC50 = 0.0551 nM,ETA)。 了解更多
  35. Asenapine HCl

    Catalog No. A15002
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    adrenergic receptor/5-HT receptor 抑制剂
    Asenapine hydrochloride抑制肾上腺素能受体(α1,α2A,α2B,α2C)的Ki为0.25-1.2 nM,还抑制5-HT受体(1A,1B,2A,2B,2C,5A,6、7),Ki为0.03- 4.0 nM。 了解更多
  36. AMD-070 HCl

    Catalog No. A14997
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    CXCR4 拮抗剂
    在CXCR4 125I-SDF抑制结合试验中,AMD-070 HCl是一种有效的选择性CXCR4拮抗剂,IC50值为13 nM,抑制T-4型HIV-1(NL4.3株)在MT-4细胞中的复制和PBMC。 了解更多
  37. SB-408124 HCl

    Catalog No. A15231
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    OX Receptor 拮抗剂
    SB408124 Hydrochloride是OX1受体的非肽拮抗剂,全细胞和膜的Ki分别为57 nM和27 nM。表现出比OX2受体高50倍的选择性。 了解更多
  38. Xylazine HCl

    Catalog No. A13434
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    Adrenergic Receptor 激动剂
    Xylazine hydrochloride是α2A-AR、α2B-AR和α2C-AR的活化剂。 了解更多
  39. Octopamine hydrochloride

    Catalog No. A13419
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    Octopamine hydrochloride是一种无脊椎生物胺神经递质,与去甲肾上腺素相关,是肾上腺素受体激动剂。 了解更多
  40. lorcaserin hydrochloride (APD-356)

    Catalog No. A12598
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    serotonin 2C receptor 激动剂
    lorcaserin hydrochloride (APD-356)是血清素2C受体激动剂,可指示与减少热量饮食和增加体育锻炼以减轻慢性体重成人管理。 了解更多
  41. Tetrahydrozoline Hydrochloride

    Catalog No. A13080
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    Adrenergic Receptor 激动剂
    Tetrahydrozoline Hydrochloride是一种引起结膜血管收缩的α激动剂。 了解更多
  42. Oxymetazoline hydrochloride

    Catalog No. A10686
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    alpha-1 adrenergic 激动剂
    Oxymetazoline是一种选择性的α-1激动剂和部分α-2激动剂局部减充血剂,以盐酸羟甲唑啉的形式使用。 了解更多
  43. Olopatadine hydrochloride

    Catalog No. A10671
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    Olopatadine hydrochloride是一种双重作用的组胺H1受体拮抗剂和肥大细胞稳定剂。 了解更多
  44. Phenoxybenzamine hydrochloride

    Catalog No. A10719
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    α-adrenergic (AR) 拮抗剂/CaM 抑制剂
    Phenoxybenzamine hydrochloride是一种细胞可渗透的,非特异性的,不可逆的α-肾上腺素(AR)拮抗剂,也可作为CaM抑制剂。 了解更多
  45. Roxatidine acetate hydrochloride

    Catalog No. A11921
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    Roxatidine acetate hydrochloride是一种用于溃疡治疗的组胺H2受体拮抗剂。 了解更多
  46. Clomipramine HCl

    Catalog No. A10231
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    5-HT Receptor 激动剂
    Clomipramine HCl是下列转运蛋白的阻滞剂:5-羟色胺转运蛋白 (SERT)(Ki = 0.14 nM),去甲肾上腺素转运蛋白(NET)(Ki = 54 nM),多巴胺转运蛋白(DAT)(Ki = 3,020 nM),甘氨酸转运蛋白(GlyT/LeuT)。 了解更多
  47. Phenylephrine HCl

    Catalog No. A11666
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    α1-adrenergic receptor 激动剂
    Phenylephrine HCl是一种选择性的α1肾上腺素能受体激动剂,主要用作减充血剂,扩张瞳孔和增加血压的药物。 了解更多
  48. Rotigotine HCl

    Catalog No. A11118
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    Dopamine Receptor 激动剂
    Rotigotine hydrochloride是一种多巴胺D2和D3受体激动剂。D2和D3的Ki值分别为13和0.71 nM。 了解更多
  49. BRL 52537 HCl

    Catalog No. A11210
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    Opioid Receptors 激动剂
    BRL 52537 hydrochloride是一种高度选择性和有效的κ阿片类激动剂(Ki = 0.24 nM)。比吗啡强25倍。 了解更多

产品 51 到 99 共 99个

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