“glucagon receptor”的搜索结果

产品 201 到 250 共 493个

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  1. FTY720 (S)-Phosphate

    Catalog No. A21324
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    S1PR1 agonist
    FTY720 (S)-Phosphate is an agonist of S1P receptor 1 (S1PR1), used in the research of acute inflammatory diseases such as acute lung injury. 了解更多
  2. LPA1 antagonist 1

    Catalog No. A21301
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    LPA1 antagonist
    LPA1 antagonist 1 is a highly selective Lysophosphatidic Acid receptor-1 (LPA1) antagonist with an IC50 of 25 nM. 了解更多
  3. Capromorelin Tartrate

    Catalog No. A21238
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    GHSR agonist
    Capromorelin Tartrate is an orally active, potent growth hormone secretagogue receptor (GHSR) agonist, with Ki of 7 nM for hGHS-R1a. 了解更多
  4. Pavinetant

    Catalog No. A21174
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    NK3R antagonist
    Pavinetant (MLE-4901) is a neurokinin-3 receptor (NK3R) antagonist. 了解更多
  5. AMG 487

    Catalog No. A21162
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    CXCR3 antagonist
    AMG 487 is an orally active and selective antagonist of CXC chemokine receptor 3 (CXCR3) which inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM, respectively. 了解更多
  6. ADX88178

    Catalog No. A20922
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    mGluR4 PAM
    ADX88178 is a potent metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) with an EC50 of 4 nM for human mGluR4. 了解更多
  7. Cenerimod

    Catalog No. A20913
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    S1P1 agonist
    Cenerimod (ACT-334441) is a potent and orally available sphingosine 1-phosphate 1 receptor (S1P1) agonist extracted from patent WO 2016184939 A1 and WO 2011007324 A1, example 1, with an EC50 of 2.7 nM. 了解更多
  8. Loxapine

    Catalog No. A18073
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    D2DR/D4DR inhibitor
    Loxapine Succinate is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent. 了解更多
  9. NPS-2143 hydrochloride

    Catalog No. A11505
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    CaSR antagonist
    NPS-2143 hydrochloride (SB-262470A hydrochloride), an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist. 了解更多
  10. Kynurenic acid sodium

    Catalog No. A20000
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    GPR35/CXCR8 agonist
    Kynurenic acid sodium, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid sodium is also an agonist of GPR35/CXCR8. 了解更多
  11. GPR35 agonist 1

    Catalog No. A12462
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    GPR35/CXCR8 agonist
    GPR35 agonist 1 (compound 50) is a potent and specific G protein-coupled receptor-35 (GPR35)/CXCR8 agonist with an EC50 of 5.8 nM, displays good druggability. 了解更多
  12. LY2922470

    Catalog No. A12181
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    GPR40 agonist
    LY2922470 is a potent, selective and orally available agonist of the G protein-coupled receptor 40 (GPR40), with EC50s of 7 nM, 1 nM and 3 nM for human GPR40, mouse GPR40 and rat GPR40, respectively. 了解更多
  13. (+)-Cloprostenol

    Catalog No. A12979
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    prostaglandin F2α (PGF2α) analogue
    (+)-Cloprostenol is a prostaglandin F2α (PGF2α) analogue, and shows selective agonistic activity at the prostaglandin receptor. 了解更多
  14. AGN 192836

    Catalog No. A13013
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    α2 adrenergic agonist
    AGN 192836 is a potent and selective α2 adrenergic agonist with EC50s of 8.7, 41 and 6.6 nM for α2A, α2B and α2C receptor, respectively. 了解更多
  15. Deramciclane

    Catalog No. A13011
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    5-HT2A and 5-HT2C receptors antagonist
    Deramciclane has a high affinity for 5-HT2A and 5-HT2C receptors; it acts as an antagonist at both receptor subtypes and has inverse agonist properties at the 5-HT2C receptors without direct stimulatory agonist. 了解更多
  16. Befetupitant

    Catalog No. A13149
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    NK1R antagonist
    Befetupitant is a high-affinity, nonpeptide, competitive tachykinin 1 receptor (NK1R) antagonist. 了解更多
  17. G15

    Catalog No. A13675
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    GPER/GPR30 antagonist
    G15 is a high affinity and selective G-protein-coupled estrogen receptor (GPER/GPR30) antagonist with a Ki of 20 nM. 了解更多
  18. DJ-V-159

    Catalog No. A18853
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    GPRC6A agonist
    DJ-V-159 is an agonist for G protein-coupled receptor family C group 6 member A (GPRC6A). 了解更多
  19. Dicarbine

    Catalog No. A18925
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    Dopamine receptor blocker
    Dicarbine blocks dopamine receptors in various brain parts and prevents the depression of the conditioned defence reflexes caused by stimulation of the mesencephalic portion of the reticular formation. Dicarbine could be used to treat patients with schizophrenia and alcoholic psychosis in clinical. 了解更多
  20. PS372424

    Catalog No. A19421
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    Human CXCR3 拮抗剂
    PS372424, a three amino-acid fragment of CXCL10, is a specific human CXCR3 agonist with anti-inflammatory activity, which inhibits the binding of CXCR3 ligand CXCL10 to CXCR3 receptor with IC50 of 42 nM. 了解更多
  21. GSK726701A

    Catalog No. A20101
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    EP4 partial agonist
    GSK726701A is a novel prostaglandin E2 receptor 4 (EP4) partial agonist with a pEC50 of 7.4. 了解更多
  22. ONO-7300243

    Catalog No. A16644
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    LPA1 antagonist
    ONO-7300243 is a novel, potent lysophosphatidic acid receptor 1 (LPA1) antagonist with IC50 of 0.16 μM. 了解更多
  23. Kynurenic acid

    Catalog No. A16581
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    GPR35/CXCR8 拮抗剂
    Kynurenic acid, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid is also an agonist of GPR35/CXCR8. 了解更多
  24. Radioprotectin-1

    Catalog No. A18628
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    LPA2 agonist
    Radioprotectin-1 is a potent and specific nonlipid agonist of lysophosphatidic acid receptor 2 (LPA2), with an EC50 value of 25 nM for murine LPA2 subtype. 了解更多
  25. AS2717638

    Catalog No. A18630
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    LPA5 antagonist
    AS2717638 is an oral active and selective lysophosphatidic acid receptor 5 (LPA5) antagonist, with an IC50 of 38 nM for hLPA5. AS2717638 also significantly improves PGE2-, PGF2α-, and AMPA-induced allodynia. 了解更多
  26. USL311

    Catalog No. A18778
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    CXCR4 拮抗剂
    USL311 is a CXCR4 receptor antagonist which prevents the binding of stromal-cell derived factor-1 (SDF-1 or CXCL12) to CXCR4. 了解更多
  27. VU0652835

    Catalog No. A18885
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    mGlu5 modulator
    VU0652835 is a metabotropic glutamate receptor subtype 5 (mGlu5) negative allosteric modulator with an IC50 of 81 nM. 了解更多
  28. Mequitazine

    Catalog No. A18206
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    Histamine H1 antagonist
    Mequitazine is a potent histamine H1 antagonist or antihistamine. It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract. 了解更多
  29. Trimebutine maleate

    Catalog No. A18115
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    ?- opioid receptor agonist
    Trimebutine Maleate is a drug with antimuscarinic and weak mu opioid agonist effects. Trimebutine Maleate modulates the calcium and potassium channels, relieves abdominal pain in patients with irritable bowel syndrome. 了解更多
  30. Pizotifen

    Catalog No. A18107
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    5-HT receptor antagonist
    Pizotifen is a serotonin antagonist which acts mainly at the 5-HT1, 5-HT2A, and 5HT2C receptors with some antihistamine activity. 了解更多
  31. Dinoprost tromethamine

    Catalog No. A17505
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    Prostaglandin Receptor inhibitor
    Dinoprost Tromethamine, also known as Dinoprost Trometamol, is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient. 了解更多
  32. Benorylate

    Catalog No. A17501
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    Prostaglandin Receptor inhibitor
    Benorilate, also known as Win-11450, is an ester of aspirin and paracetamol with analgesic, antipyretic, and anti-inflammatory activity used in the treatment of rheumatoid diseases. Benorilate has less severe side effects than aspirin. 了解更多
  33. Loxapine Succinate

    Catalog No. A17347
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    D2DR and D4DR inhibitor
    Loxapine Succinate is a D2DR and D4DR inhibitor and serotonergic receptor antagonist. Loxapine succinate is an antipsychotic agent used in schizophrenia. 了解更多
  34. Dulaglutide

    Catalog No. A16987
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    GLP-1 receptor 激动剂
    Dulaglutide是胰高血糖素样肽1(GLP-1)受体激动剂。 了解更多
  35. Volinanserin

    Catalog No. A17115
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    5-HT2A receptor 拮抗剂
    Volananserin是高度选择性的5-HT2A受体拮抗剂。 了解更多
    • 最新产品

    TCS-OX2-29 HCl

    Catalog No. A17136
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    OX2 receptor 拮抗剂
    TCS-OX2-29 HCl是一种选择性OX2受体拮抗剂,IC50值为40 nM。 了解更多
  36. NSC-23026

    Catalog No. A17151
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    CXCR4 receptor modulator
    NSC-23026是CXCR4受体调节剂。 了解更多
  37. LY 344864 racemate

    Catalog No. A17015
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    5-HT1F receptor 激动剂
    LY 344864 racemate是5-HT1F受体激动剂。 了解更多
  38. VU6005649

    Catalog No. A17023
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    CNS penetrant mGlu7/8 receptor 激动剂
    VU6005649是一种CNS渗透性mGlu7/8受体激动剂,对mGlu7受体和mGlu8受体的EC50分别为0.65 μM和2.6 μM。 了解更多
  39. Temanogrel

    Catalog No. A17094
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    5-HT(2A) receptor 激动剂
    Temanogrel,也称为APD791,是一种高度选择性的5-羟基色胺2A受体反向激动剂,正在开发中,用于治疗动脉血栓形成。 了解更多
  40. GSK-269984A

    Catalog No. A17096
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    EP1 receptor 拮抗剂
    GSK-269984A是新型的EP1受体拮抗剂。pIC50 值为 7.9。 了解更多
  41. Bevenopran

    Catalog No. A17110
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    opioid receptor antagonis
    Bevenopran,也称为CB-5945,ADL-5945,MK-2402,OpRA III,是一种外周选择性μ-和δ-阿片样物质受体拮抗剂。 了解更多
  42. MRS1706

    Catalog No. A16868
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    adenosine A2B receptor 反向激动剂
    MRS1706是一种选择性腺苷A2B受体反向激动剂,对人A2B,A1,A2A和A3受体的Ki值分别为1.39、157、112和230 nM。 了解更多
  43. MRS1186

    Catalog No. A16870
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    Adenosine A3 receptor 拮抗剂
    MRS1186是一种有效的选择性人腺苷A3受体(hA3AR)拮抗剂,Ki为7.66 nM。 了解更多
  44. MRS1177

    Catalog No. A16871
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    Adenosine A3 receptor 拮抗剂
    MRS1177是一种有效的选择性人腺苷A3受体(hA3AR)拮抗剂,Ki为0.3 nM。 了解更多
  45. LP-211

    Catalog No. A16898
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    5-HT7 receptor 激动剂
    LP-211是血清素5-HT7受体的选择性激动剂,在大鼠克隆的5-HT7受体上的Ki值为0.58 nM,选择性是5-HT1A受体的300倍以上。 了解更多
  46. Tradipitant

    Catalog No. A16918
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    NK1 receptor 拮抗剂
    Tradipitant,也称为VLY-686和LY686017,是第二代神经激肽1受体拮抗剂,在临床前焦虑模型中表现出活性。 了解更多
  47. Eucalyptol

    Catalog No. A15662
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    5-HT3 receptor 抑制剂
    Eucalyptol是一种在桉树和其他植物中发现的双环单萜。它是5-HT3受体,钾通道,TNF-α的抑制剂。和IL-1β。 了解更多
  48. Senktide

    Catalog No. A16945
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    NK3 receptor 激动剂
    Senktide是神经介素K3(NK3)受体的有效选择性激动剂(EC50 = 0.5-3 nM)。 了解更多
  49. CGRP 8-37 (human)

    Catalog No. A16949
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    CGRP receptor 拮抗剂
    CGRP 8-37 (human)是人降钙素基因相关肽(hCGRP)片段,也是CGRP受体的拮抗剂。序列:Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn- Val-Gly-Ser-Lys-Ala-Phe;VTHRLAGLLSRSGGVVKNNFVPTNVGSKAF。 了解更多

产品 201 到 250 共 493个

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