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Auglurant

Catalog No. A20958
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mGlu5 antagonist

Auglurant (VU0424238) is a novel and selective mGlu5 antagonist with an IC50 value of 11 nM (rat) and an IC50 value of 14 nM (human). Auglurant (VU0424238) has an acceptable CNS penetration. 了解更多

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Basimglurant

Catalog No. A21225
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mGlu5 negative allosteric modulator

Basimglurant (RG7090) is a potent, selective and orally available mGlu5 negative allosteric modulator with a Kd of 1.1 nM. 了解更多

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