你的浏览器似乎禁用了 JavaScript。
您必须在浏览器中启用JavaScript才能使用本网站的功能。

微信关注
申请试用装

主页 /
搜索结果：“sb269970 hcl”

“sb269970 hcl”的搜索结果

Quick View
Pyrithioxin dihydrochloride

Catalog No. A18137
Quick View

添加到收藏
neurotropic agent

Pyrithioxine HCl is a neurotropic agent which reduces permeability of blood-brain barrier to phosphate. It has no vitamin B6 activity. 了解更多

Bulk Inquiry
Quick View
Rufloxacin hydrochloride

Catalog No. A18255
Quick View

添加到收藏
Rufloxacin HCl is a quinolone antibiotic and antibacterial. It inhibits B-cell differentiation in human mononuclear cells and acts as an inhibitor of Topo. 了解更多

Bulk Inquiry
Quick View
Difloxacin HCl

Catalog No. A18297
Quick View

添加到收藏
Difloxacin is a second-generation, broad-spectrum, concentration dependent antibiotic. 了解更多

Bulk Inquiry
Quick View
Ziprasidone hydrochloride

Catalog No. A16790
Quick View

添加到收藏
5-HT (serotonin)/dopamine receptor antagonist

Ziprasidone Hcl(CP-88059 Hcl) is a combined 5-HT (serotonin) and dopamine receptor antagonist which exhibits potent effects of antipsychotic activity. 了解更多

Bulk Inquiry
Quick View
MK-2206 2HCl

Catalog No. A10003
Quick View

添加到收藏
AKT 抑制剂

MK-2206 2HCl是Akt1/2/3的高选择性抑制剂，IC50分别为8 nM/12 nM/65 nM。了解更多

Product Citations (17)

Bulk Inquiry Free Sample
- Ming-Chun Hung, .et al. AKT phosphorylation as a predictive biomarker for PI3K/mTOR dual inhibition-induced proteolytic cleavage of mTOR companion proteins in small cell lung cancer, Cell Biosci, 2022, 12: 122 PMID: 35918763
- Yusuke Murase, .et al. Antitumor activity of the dual PI3K/mTOR inhibitor gedatolisib and the involvement of ABCB1 in gedatolisib resistance in canine tumor cells, Oncol Rep, 2022, Apr;47(4):61 PMID: 35088890
- Majid Momeny, .et al. Cediranib, a pan-inhibitor of vascular endothelial growth factor receptors, inhibits proliferation and enhances therapeutic sensitivity in glioblastoma cells, Life Sci, 2021, Dec 15;287:120100 PMID: 34715143
- Ali Nasrollahzadeh, .et al. Anti-proliferative activity of disulfiram through regulation of the AKT-FOXO axis: A proteomic study of molecular targets, Biochim Biophys Acta Mol Cell Res, 2021, Jun 26;1868(10):119087 PMID: 34182011
- Rona Aviram, .et al. Ultradian rhythms of AKT phosphorylation and gene expression emerge in the absence of the circadian clock components Per1 and Per2, PLoS Biol, 2021, Dec 30;19(12):e3001492 PMID: 34968386
- Cristina Rosell??-Busquets, .et al. Nystatin Regulates Axonal Extension and Regeneration by Modifying the Levels of Nitric Oxide, Front Mol Neurosci, 2020, 13: 56 PMID: 32317932
- Dai-Chi Liu, .et al. Chronic Activation of Gp1 mGluRs Leads to Distinct Refinement of Neural Network Activity Through Non-Canonical p53 and Akt Signaling, eNeuro, 2020, Mar 27;7(2):ENEURO.0438-19.2020 PMID: 32161037
- Nishihama K, .et al. Anti-apoptotic activity of human matrix metalloproteinase-2 attenuates diabetes mellitus, Metabolism, 2018, May;82:88-99 PMID: 29366755
- J Wei, .et al. Profiling the surface proteome identifies actionable biology for TSC1 mutant cells beyond mTORC1 signaling, bioRxiv, 2018, 2018
- Joo Sang Lee, .et al. Harnessing synthetic lethality to predict the response to cancer treatment, Nat Commun, 2018, 9: 2546 PMID: 29959327
- Wan-Ting Hu, .et al. The O-glycosylating enzyme GALNT2 suppresses the malignancy of gastric adenocarcinoma by reducing EGFR activities, Am J Cancer Res, 2018, 8(9): 1739-1751 PMID: 30323967
- Angela M. Gocher, .et al. Akt activation by Ca2+/calmodulin-dependent protein kinase kinase 2 (CaMKK2) in ovarian cancer cells, J Biol Chem, 2017, Aug 25; 292(34): 14188-14204 PMID: 28634229
- Kusuyama J, .et al. Constitutive activation of p46JNK2 is indispensable for C/EBPδ induction in the initial stage of adipogenic differentiation, Biochem J, 2017, Oct 5;474(20):3421-3437 PMID: 28887384
- Pi-Lin Sung, .et al. Periostin in tumor microenvironment is associated with poor prognosis and platinum resistance in epithelial ovarian carcinoma, Oncotarget, 2016, Jan 26; 7(4): 4036-4047 PMID: 26716408
- Mikaël M. Martino, .et al. Inhibition of IL-1R1/MyD88 signalling promotes mesenchymal stem cell-driven tissue regeneration, Nat Commun, 2016, 7: 11051 PMID: 27001940
- Dominik Schulz, .et al. HNSCC cells resistant to EGFR pathway inhibitors are hypermutated and sensitive to DNA damaging substances, Am J Cancer Res, 2016, 6(9): 1963-1975 PMID: 27725902
- Jewett KA, .et al. The tumor suppressor p53 guides GluA1 homeostasis through Nedd4-2 during chronic elevation of neuronal activity., J Neurochem., 2015, Oct;135(2):226-33 PMID: 26250624
Quick View
Y-27632 2HCl

Catalog No. A11001
Quick View

添加到收藏
ROCK 抑制剂

Y-27632是一种Rho相关的线圈激酶（ROCK）抑制剂，可提高人类胚胎干细胞（hESCs）的克隆效率。比对其他激酶包括PKC，cAMP依赖性蛋白激酶，MLCK和PAK的作用强200多倍。了解更多

Product Citations (27)

Bulk Inquiry Free Sample
- Sergio Pedraza-Arevalo, .et al. Differentiation of beta-like cells from human induced pluripotent stem cell-derived pancreatic progenitor organoids, STAR Protoc, 2022, Aug 30;3(3):101656 PMID: 36092820
- Ji-Hyun Lee, .et al. p57Kip2 imposes the reserve stem cell state of gastric chief cells, Cell Stem Cell, 2022, May 5; 29(5): 826-839 PMID: 35523142
- Adam Pietrobon, .et al. Renal organoid modeling of tuberous sclerosis complex reveals lesion features arise from diverse developmental processes, Cell Rep, 2022, Jul 5;40(1):111048 PMID: 35793620
- Sarkawt Hamad, .et al. High-efficient serum-free differentiation of endothelial cells from human iPS cells, Stem Cell Res Ther, 2022, Jun 11;13(1):251 PMID: 35690874
- Stasia Krishtul, .et al. Development of a bioactive microencapsulation platform incorporating decellularized extracellular matrix to entrap human induced pluripotent stem cells for versatile biomedical applications, Polym Adv Technol, 2022, 33( 11): 3842-3852
- Peter T Ruane, .et al. Trophectoderm differentiation to invasive syncytiotrophoblast is promoted by endometrial epithelial cells during human embryo implantation, Hum Reprod, 2022, Apr 1;37(4):777-792 PMID: 35079788
- Takayuki Miyoshi, .et al. Successful induction of human chemically induced liver progenitors with small molecules from damaged liver, J Gastroenterol, 2022, Jun;57(6):441-452 PMID: 35294680
- Ana-Maria Cujba, .et al. An HNF1α truncation associated with maturity-onset diabetes of the young impairs pancreatic progenitor differentiation by antagonizing HNF1β function, Cell Rep, 2022, Mar 1;38(9):110425 PMID: 35235779
- Dan Zhao, .et al. From crypts to enteroids: establishment and characterization of avian intestinal organoids, Poult Sci, 2022, Mar; 101(3): 101642 PMID: 35016046
- Antigoni Gogolou, .et al. Generating Enteric Nervous System Progenitors from Human Pluripotent Stem Cells, Curr Protoc, 2021, Jun;1(6):e137 PMID: 34102038
- Tiago De Oliveira, .et al. Effects of the Novel PFKFB3 Inhibitor KAN0438757 on Colorectal Cancer Cells and Its Systemic Toxicity Evaluation In Vivo, Cancers (Basel), 2021, Mar 2;S2451-9456(21)00095-7 PMID: 33671096
- Denise Muller, .et al. Functional apoptosis profiling identifies MCL-1 and BCL-xL as prognostic markers and therapeutic targets in advanced thymomas and thymic carcinomas, BMC Med, 2021, Nov 16;19(1):300 PMID: 34781947
- Ayumi Horikawa, .et al. A simple method of hiPSCs differentiation into insulin-producing cells is improved with vitamin C and RepSox, PloS one, 2021, Jul 12;16(7):e0254373 PMID: 34252142
- Hayato Mizuta, .et al. Gilteritinib overcomes lorlatinib resistance in ALK-rearranged cancer, Nat Commun, 2021, Feb 24;12(1):1261 PMID: 33627640
- Scott Bell, .et al. Lesch-Nyhan disease causes impaired energy metabolism and reduced developmental potential in midbrain dopaminergic cells, Stem Cell Reports, 2021, Jul 13;16(7):1749-1762 PMID: 34214487
- Shenyang Li, .et al. Effect of porcine corneal stromal extract on keratocytes from SMILE-derived lenticules, J Cell Mol Med, 2020, Dec 20;25(2):1207-1220 PMID: 33342057
- Takao FUCHIGAMI, .et al. Ameloblastoma cell lines derived from different subtypes demonstrate distinct developmental patterns in a novel animal experimental model, J Appl Oral Sci, 2020, 28: e20190558 PMID: 32348439
- Jing-Yu Lin, .et al. In vitro expansion of pancreatic islet clusters facilitated by hormones and chemicals, Cell Discov, 2020, 6: 20 PMID: 32284878
- Yu Huang, .et al. Development of Bifunctional Three-Dimensional Cysts from Chemically Induced Liver Progenitors, Stem Cells Int, 2019, 2019: 3975689 PMID: 31565060
- XinYan, .et al. Establishment of CSUASOi001-A, a non-integrated induced pluripotent stem cell line from urine-derived cells of a Chinese patient carrying RS1 gene mutation, Stem Cell Res, 2019, May 17 PMID: 31141763
- Daniela F. Duarte Campos, .et al. Corneal bioprinting utilizing collagen?\based bioinks and primary human keratocytes, J Biomed Mater Res A, 2019, April 22 PMID: 31012205
- Scott Bell, .et al. Mutations in ACTL6B Cause Neurodevelopmental Deficits and Epilepsy and Lead to Loss of Dendrites in Human Neurons, Am J Hum Genet, 2019, May 2;104(5):815-834 PMID: 31031012
- Ooi J, .et al. Unbiased Profiling of Isogenic Huntington Disease hPSC-Derived CNS and Peripheral Cells Reveals Strong Cell-Type Specificity of CAG Length Effects, Cell Rep, 2019, Feb 26;26(9):2494-2508 PMID: 30811996
- Scott Bell, .et al. Disruption of GRIN2B Impairs Differentiation in Human Neurons, Stem Cell Reports, 2018, Jul 10; 11(1):183-196 PMID: 29937144
- Christina Zarouchlioti, .et al. Antisense Therapy for a Common Corneal Dystrophy Ameliorates TCF4 Repeat Expansion-Mediated Toxicity, Am J Hum Genet, 2018, Apr 5; 102(4): 528-539 PMID: 29526280
- Ai Takemoto, .et al. A critical role of platelet TGF-β release in podoplanin-mediated tumour invasion and metastasis, Sci Rep, 2017, 7: 42186 PMID: 28176852
- Scott Bell, .et al. A Rapid Pipeline to Model Rare Neurodevelopmental Disorders with Simultaneous CRISPR/Cas9 Gene Editing, Stem Cells Transl Med, 2017, Mar; 6(3): 886-896 PMID: 28170165
Quick View
LY335979 (Zosuquidar 3HCl)

Catalog No. A10549
Quick View

添加到收藏
P-gp modulator

LY335979 (Zosuquidar trihydrochloride)是一种强效高选择性P-gp抑制剂。了解更多

Product Citations (1)

Bulk Inquiry Free Sample
- Leo Shen, .et al. A forward genetic screen identifies modifiers of rocaglate responsiveness, Sci Rep, 2021, Sep 16;11(1):18516 PMID: 34531456
Quick View
Vatalanib (PTK787) 2HCl

Catalog No. A10967
Quick View

添加到收藏
VEGFR 抑制剂

Vatalanib (PTK787) 2HCl是一种小分子蛋白激酶抑制剂，可抑制抑制所有已知VEGF受体以及血小板衍生的生长因子受体β和c-kit的血管生成，但对VEGFR-2的选择性最高。了解更多

Bulk Inquiry Free Sample
Quick View
MCOPPB 3HCl

Catalog No. A10561
Quick View

添加到收藏
NOP receptor 激动剂

MCOPPB 3HCl是一种用作伤害感受器受体的有效和选择性激动剂的化合物，pKi为10.07。了解更多

Bulk Inquiry Free Sample
Quick View
Naftopidil 2HCl

Catalog No. A10619
Quick View

添加到收藏
5-HT1A and α1-adrenergic receptor 拮抗剂

Naftopidil 2HCl是选择性5-HT1A和α1-肾上腺素能受体拮抗剂，IC50分别为0.1μM和0.2μM。了解更多

Bulk Inquiry
Quick View
Dimebon 2HCl

Catalog No. A10312
Quick View

添加到收藏
Neuroprotectant

Dimebon dihydrochloride是一种非选择性的抗组胺药，具有增强认知能力。了解更多

Bulk Inquiry Free Sample
Quick View
Manidipine 2HCl

Catalog No. A10554
Quick View

添加到收藏
Manidipine dihydrochloride是Manidipine的HCl盐形式，Manidipine是Ca2+电流的钙通道阻滞剂，IC50为2.6 nM。了解更多

Product Citations (1)

Bulk Inquiry
- Noriaki Ikemura,, .et al. Inhibitory effects of antihypertensive drugs on human cytochrome P450 2J2 activity: Potent inhibition by azelnidipine and manidipine, Chem -Biol Interact, 2019, 306:1-9
Quick View
Meclizine 2HCl

Catalog No. A11700
Quick View

添加到收藏
Meclizine是人类的孕烷X受体（hPXR）激动剂。它具有抗胆碱能，中枢神经系统抑制作用和局部麻醉作用。其止吐和抗眩晕作用尚不完全清楚，但其主要的抗胆碱能特性是部分原因。了解更多

Bulk Inquiry
Quick View
Vanoxerine 2HCl (GBR-12909)

Catalog No. A10725
Quick View

添加到收藏
dopamine re-uptake 抑制剂

Vanoxerine 2HCl (GBR-12909)是哌嗪衍生物，是一种有效的、选择性的多巴胺摄取（dopamine uptake）抑制剂。了解更多

Bulk Inquiry Free Sample
Quick View
Plerixafor 8HCl (DB06809)

Catalog No. A10913
Quick View

添加到收藏
CXCR4 拮抗剂

Plerixafor 8HCl (DB06809)是CXCR4趋化因子受体拮抗剂，作用于CXCR4和CXCL12介导调节的趋化性， IC50分别为44 nM和5.7 nM。了解更多

Product Citations (3)

Bulk Inquiry Free Sample
- Mei Zheng, .et al. CXCL12 inhibits hair growth through CXCR4, Biomed Pharmacother, 2022, Jun;150:112996 PMID: 35462338
- Asiedu KO, .et al. Bone marrow cell homing to sites of acute tibial fracture: 89Zr-oxine cell labeling with positron emission tomographic imaging in a mouse model, EJNMMI Res, 2018, Dec 13;8(1):109 PMID: 30547233
- Kingsley O. Asiedu, .et al. Bone marrow cell trafficking analyzed by 89Zr-oxine positron emission tomography in a murine transplantation model, Clin Cancer Res, 2017, Jun 1; 23(11): 2759-2768 PMID: 27965305
Quick View
Pramipexole dihydrochloride monohyrate

Catalog No. A10747
Quick View

添加到收藏
Dopamine Receptor 激动剂

Pramipexole dihydrochloride monohyrate是非麦角灵类的多巴胺激动剂，适用于治疗早期帕金森氏病（PD）和不安腿综合征（RLS）。了解更多

Bulk Inquiry
Quick View
BMS-790052 2HCl

Catalog No. A11336
Quick View

添加到收藏
NS5A 抑制剂

BMS-790052 2HCl是一种NS5A抑制剂，用于治疗丙型肝炎病毒(HCV)感染。了解更多

Product Citations (1)

Bulk Inquiry
- Shirasaki T, .et al. Impaired interferon signaling in chronic hepatitis C patients with advanced fibrosis via the transforming growth factor beta signaling pathway., Hepatology., 2014, 60(5):1519-30 PMID: 24962339
Quick View
B-HT 920 2HCl

Catalog No. A11341
Quick View

添加到收藏
D2 receptor 激动剂

B-HT 920 2HCl是一种多巴胺激动剂，已被提议用作抗帕金森病药物。它还具有α1肾上腺素能和α2肾上腺素能激动剂活性。了解更多

Bulk Inquiry
Quick View
H 89 2HCl

Catalog No. A11935
Quick View

添加到收藏
PKA 抑制剂

H 89 dihydrochloride是一种可渗透细胞的，选择性的，可逆的，具有ATP竞争性的有效蛋白激酶抑制剂。了解更多

Product Citations (2)

Bulk Inquiry Free Sample
- Guo Q, .et al. Antineuropathic pain actions of Wu-tou decoction resulted from the increase of neurotrophic factor and decrease of CCR5 expression in primary rat glial cells, Biomed Pharmacother, 2020, Mar;123:109812 PMID: 31945696
- Y Kaibori, .et al. EphA2 phosphorylation at Ser897 by the Cdk1/MEK/ERK/RSK pathway regulates M-phase progression via maintenance of cortical rigidity, the FASEB Journal, 2019, Jan 22:fj201801519RR PMID: 30668924
Quick View
GBR-12935 2HCl

Catalog No. A11937
Quick View

添加到收藏
DAT and SLC6A2 抑制剂

GBR-12935 dihydrochloride是一种有效的选择性多巴胺再摄取抑制剂。了解更多

Bulk Inquiry Free Sample
Quick View
Cetirizine Dihydrochloride

Catalog No. A10195
Quick View

添加到收藏
Cetirizine Dihydrochloride是第二代抗组胺药，是羟嗪的主要代谢产物，是用于治疗过敏，花粉症，血管性水肿和荨麻疹的消旋选择性H1受体反向激动剂。了解更多

Bulk Inquiry Free Sample
Quick View
Quinacrine 2HCl

Catalog No. A13242
Quick View

添加到收藏
Quinacrine dihydrochloride是组胺N-甲基转移酶抑制剂。了解更多

Bulk Inquiry
Quick View
Talniflumate

Catalog No. A13339
Quick View

添加到收藏
CaCC blocker

Talniflumate是一种钙激活的氯离子通道（CaCC）（hCLCA1/mCLCA3）阻滞剂；在细胞培养和动物模型中减少粘蛋白的合成和释放。了解更多

Bulk Inquiry
Quick View
TAS 103 2HCl

Catalog No. A14141
Quick View

添加到收藏
topoisomerase I/II 抑制剂

TAS 103 2HCl，也称为BMS-247615，是一种喹啉衍生物，在鼠和人肿瘤模型中显示出抗肿瘤活性。了解更多

Bulk Inquiry
Quick View
Puromycin 2HCl

Catalog No. A14268
Quick View

添加到收藏
protein synthesis 抑制剂

Puromycin 2HCl是一种氨基核苷抗生素，可作为蛋白质合成抑制剂。了解更多

Bulk Inquiry
Quick View
Nitrarine 2HCl

Catalog No. A13911
Quick View

添加到收藏
Nitrarine dihydrochloride在实验性心律不齐中具有镇静作用。它的抗心律不齐特性是由于其对膜的稳定作用及其冠状动脉扩张作用。Nitrarine dihydrochloride是新卡因胺和奎尼丁的3-4倍，其效果持续时间是这些产品的2-5倍。了解更多

Bulk Inquiry
Quick View
Dorsomorphin 2HCl

Catalog No. A13720
Quick View

添加到收藏
BMP 抑制剂

Dorsomorphin 2HCl (BML-275)是BMP信号传导的选择性小分子抑制剂，可促进胚胎干细胞的心肌发生。Dorsomorphin通过抑制骨形态发生蛋白信号转导逆转乳腺癌起始细胞的间质表型。了解更多

Product Citations (1)

Bulk Inquiry Free Sample
- Kameshima S, .et al. Eukaryotic elongation factor 2 (eEF2) kinase/eEF2 plays protective roles against glucose deprivation-induced cell death in H9c2 cardiomyoblasts, Apoptosis, 2019, Feb 8 PMID: 30737648
Quick View
Glycyl-H 1152 2HCl

Catalog No. A13659
Quick View

添加到收藏
ROCK 抑制剂

Glycyl-H 1152 2HCl是一种选择性有效的ROCK抑制剂（ROCKII，Aurora A，CAMKII，PKG，PKA和PKC的IC50值分别为0.0118、2.35、2.57、3.26，> 10和> 10 uM。）了解更多

Bulk Inquiry
Quick View
5-Iodo-A-85380 2HCl

Catalog No. A13639
Quick View

添加到收藏
nAChR 激动剂

5-Iodo-A-85380 2HCl是针对a4b2和a6b2烟碱乙酰胆碱受体的强效亚型选择性激动剂。了解更多

Bulk Inquiry
Quick View
RN-1 2HCl

Catalog No. A14344
Quick View

添加到收藏
MAO 抑制剂

RN-1 2HCl对LSD1的选择性优于单胺氧化酶(MAO)-A和MAO-B（在辣根过氧化物酶偶联测定中，IC50值分别为70 nM，0.51和2.79 μM）。了解更多

Bulk Inquiry
Quick View
CP 31398 2HCl

Catalog No. A13522
Quick View

添加到收藏
p53 stabilizer

CP 31398 2HCl已显示出可作为p53的稳定剂，并促进癌细胞系中p53的活性。了解更多

Bulk Inquiry
Quick View
A 943931 2HCl

Catalog No. A13442
Quick View

添加到收藏
Histamine H4 receptor 拮抗剂

943931 2HCl是一种有效的选择性组胺H4受体拮抗剂（人和大鼠受体的pKi值分别为7.15和8.12）。了解更多

Bulk Inquiry
Quick View
JP 1302 2HCl

Catalog No. A13412
Quick View

添加到收藏
α2C 拮抗剂

JP 1302 2HCl是一种强效和选择性α2C拮抗剂。了解更多

Bulk Inquiry
Quick View
AT7867 2HCl

Catalog No. A15006
Quick View

添加到收藏
Akt 抑制剂

AT7867 dihydrochloride是一种有效的ATP竞争性Akt1/2/3和p70S6K/PKA抑制剂，IC50分别为32 nM/17 nM/47 nM和85 nM/20 nM，在AGC激酶家族之外几乎没有活性。了解更多

Bulk Inquiry
Quick View
KX2-391 2HCl

Catalog No. A11471
Quick View

添加到收藏
Src 抑制剂

Tirbanibulin dihydrochloride是首个靶向Src肽底物位点的临床Src抑制剂(拟肽类),在癌细胞系中GI50为9-60 nM。了解更多

Bulk Inquiry
Quick View
K-7174 2HCl

Catalog No. A15446
Quick View

添加到收藏
Cell adhesion 抑制剂

K-7174 dihydrochloride是一种新型的细胞粘附抑制剂；抑制由IL-1beta或TNF-alpha诱导的血管细胞粘附分子1（VCAM-1）的表达。了解更多

Bulk Inquiry
Quick View
Pyridoxamine 2HCl

Catalog No. A16199
Quick View

添加到收藏
Pyridoxamine 2HCl是维生素B6的一种形式。化学上，它基于吡啶环结构，具有羟基，甲基，氨甲基和羟甲基取代基。了解更多

Bulk Inquiry
Quick View
Cyclizine 2HCl

Catalog No. A16472
Quick View

添加到收藏
Histamine H1 receptor 拮抗剂

Cyclizine 2HCl是具有组胺H1受体拮抗剂活性的哌嗪衍生物。了解更多

Bulk Inquiry
Quick View
Azacosterol

Catalog No. A13295
Quick View

添加到收藏
24-DHCR 抑制剂

Azacosterol可作为24-脱氢胆固醇还原酶（24-DHCR）的抑制剂，可防止去甾醇形成胆固醇。了解更多

Bulk Inquiry
Quick View
HAX1 Human

Catalog No. AP0623
Quick View

添加到收藏
HCLS1 Associated Protein X-1 Human Recombinant 了解更多

Bulk Inquiry
Quick View
HAX1 Antibody

Catalog No. AP3109
Quick View

添加到收藏
HCLS1-associated protein X-1, Mouse Anti Human 了解更多

Bulk Inquiry
Quick View
GW791343 trihydrochloride

Catalog No. A21204
Quick View

添加到收藏
P2X7 allosteric modulator

GW791343 3Hcl is a P2X7 allosteric modulator; exhibits species-specific activity and acts as a negative allosteric modulator of human P2X7 (pIC50 = 6.9 - 7.2). 了解更多

Bulk Inquiry
Quick View
MCOPPB triHydrochloride

Catalog No. A21722
Quick View

添加到收藏
nociceptin receptor agonist

MCOPPB 3Hcl is a nociceptin receptor agonist with pKi of 10.07; weaker activity at other opioid receptors. 了解更多

Bulk Inquiry
Quick View
Lexibulin dihydrochloride

Catalog No. A21774
Quick View

添加到收藏
tubulin polymerisation inhibitor

Lexibulin 2Hcl (CYT-997 2Hcl) is a potent tubulin polymerisation inhibitor with IC50 of 10-100 nM in cancer cell lines; with potent cytotoxic and vascular disrupting activity in vitro and in vivo. 了解更多

Bulk Inquiry
Quick View
Irinotecan HCl Trihydrate (Campto)

Catalog No. A10479
Quick View

添加到收藏
Topoisomerase 抑制剂

Irinotecan (CPT 11)是喜树碱家族的一种化合物，是参与细胞DNA复制和转录的拓扑异构酶1的抑制剂。了解更多

Bulk Inquiry Free Sample
Quick View
Pazopanib HCl (GW786034)

Catalog No. A10699
Quick View

添加到收藏
VEGFR/PDGFR/FGFR 抑制剂

Pazopanib HCl (GW786034)是VEGFR-1，VEGFR-2，VEGFR-3，PDGFR-a/β和c-kit的有效且选择性的多靶点酪氨酸激酶抑制剂，可阻止肿瘤生长并抑制血管生成。了解更多

Product Citations (4)

Bulk Inquiry Free Sample
- Aya Hasan Alshammari, .et al. Discrimination of hand-foot skin reaction caused by tyrosine kinase inhibitors based on direct keratinocyte toxicity and vascular endothelial growth factor receptor-2 inhibition, Biochem Pharmacol, 2022, Mar;197:114914 PMID: 35041812
- Majid Momeny, .et al. Cediranib, a pan-inhibitor of vascular endothelial growth factor receptors, inhibits proliferation and enhances therapeutic sensitivity in glioblastoma cells, Life Sci, 2021, Dec 15;287:120100 PMID: 34715143
- Hideharu Yamada, .et al. lncRNA HAR1B has potential to be a predictive marker for pazopanib therapy in patients with sarcoma, Oncol Lett, 2021, Jun;21(6):455 PMID: 33907565
- Majid Momeny, .et al. Cediranib, an inhibitor of vascular endothelial growth factor receptor kinases, inhibits proliferation and invasion of prostate adenocarcinoma cells, Eur J Pharmacol, 2020, 882:173298
Quick View
Azelastine HCl (Allergodil)

Catalog No. A10117
Quick View

添加到收藏
Azelastine HCl (Allergodil)是有效的第二代选择性组胺拮抗剂（组胺-H1-受体拮抗剂）。了解更多

Bulk Inquiry Free Sample
Quick View
Naltrexone HCl

Catalog No. A11723
Quick View

添加到收藏
Naltrexone HCl是一种阿片受体拮抗剂，主要用于治疗酒精依赖和阿片依赖。了解更多

Bulk Inquiry Free Sample
Quick View
Diltiazem HCl

Catalog No. A10311
Quick View

添加到收藏
Diltiazem HCl是一种非二氢吡啶（非DHP）药物，称为钙通道阻滞剂，用于治疗高血压，心绞痛和某些类型的心律不齐。了解更多

Bulk Inquiry Free Sample
Quick View
Spectinomycin HCl

Catalog No. A10861
Quick View

添加到收藏
Spectinomycin HCl是可用于治疗细菌感染，淋病的抗生素。了解更多

Bulk Inquiry Free Sample

联系我们

Not your Region? View all Distributors

最近查看过的产品

PSN632408

ADOOQ 产品质量保证

Guaranteed product quality, 365 days Unconditional Return & Replacement

We promise all products to perform as described.