“alpha ergocryptine”的搜索结果

产品 301 到 350 共 642个

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  1. Argininic acid

    Catalog No. A18854
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    Argininic acid is an α-amino acid that is used in the biosynthesis of proteins. 了解更多
  2. DCVC

    Catalog No. A12447
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    DCVC inhibits pathogen-stimulated TNF-α in human extra placental membranes in vitro. 了解更多
  3. TES-1025

    Catalog No. A13284
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    ACMSD inhibitor
    TES-1025 is a potent and selective human α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase (ACMSD) inhibitor with an IC50 of 13??3 nM. 了解更多
  4. Dactolisib Tosylate

    Catalog No. A11327
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    dual PI3K and mTOR kinase inhibitor
    Dactolisib Tosylate (BEZ235 Tosylate) is a dual PI3K and mTOR kinase inhibitor with IC50 values of 4, 75, 7, 5 nM for PI3Kα, β, γ, δ, respectively. Dactolisib Tosylate (BEZ235 Tosylate) inhibits mTORC1 and mTORC2. 了解更多
  5. Parsaclisib

    Catalog No. A13561
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    PI3Kδ inhibitor
    Parsaclisib is a potent and selective PI3Kδ inhibitor, with an IC50 of 1 nM at 1 mM ATP, and shows appr 20,000-fold selectivity for PI3Kα, PI3Kβ, PI3Kγ and 57 other kinases. 了解更多
  6. Apratastat

    Catalog No. A13330
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    dual TACE/MMPs inhibitor
    Apratastat is an orally active, potent, and reversible dual inhibitor of tumor necrosis factor-α converting enzyme (TACE) and matrix metalloproteinases (MMPs) . 了解更多
  7. TOFA

    Catalog No. A12276
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    ACCA inhibitor
    TOFA (RMI14514;MDL14514) is an allosteric inhibitor of acetyl-CoA carboxylase-α (ACCA ). 了解更多
  8. Elacestrant

    Catalog No. A12244
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    Estrogen receptor degrader
    Elacestrant (RAD1901) is an orally available selective estrogen receptor degrader (SERD) with IC50s of 48 and 870 nM for ERα and ERβ, respectively. 了解更多
  9. MDRTB-IN-1

    Catalog No. A13440
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    MDRTB-IN-1 (5aα) is an antibiotic which is against Mycobacterium tuberculosis H37Rv with a MIC90 value of 10.5 μM. 了解更多
  10. GLPG0187

    Catalog No. A13423
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    Integrin receptor antagonist
    GLPG0187 is a broad spectrum integrin receptor antagonist with antitumor activity; inhibits αvβ1-integrin with an IC50 of 1.3 nM. 了解更多
  11. Tyrosine kinase-IN-1

    Catalog No. A12486
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    multi-targeted tyrosine kinase inhibitor
    Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor with IC50s of 4, 20, 4, 2 nM for KDR, Flt-1, FGFR1 and PDGFRα, respectively. 了解更多
  12. Kynurenic acid sodium

    Catalog No. A20000
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    GPR35/CXCR8 agonist
    Kynurenic acid sodium, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid sodium is also an agonist of GPR35/CXCR8. 了解更多
  13. BOC-D-FMK

    Catalog No. A11356
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    caspase inhibitor
    Boc-D-FMK is a cell-permeable, irreversible and broad spectrum caspase inhibitor; inhibits apoptosis stimulated by TNF-α with an IC50 of 39 ?M. 了解更多
  14. ENMD-119

    Catalog No. A20915
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    ENMD-119 is a 2-methoxyestradiol analogue with antiproliferative and antiangiogenic activity, and is suitable for inhibiting HIF-1α and STAT3 in human HCC cells. 了解更多
  15. FR 167653 free base

    Catalog No. A21110
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    p38 MAPK inhibitor
    FR 167653 free base, an orally active and selective p38 MAPK inhibitor, is a potent suppressor of TNF-α and IL-1β production via specific inhibition of p38 MAPK activity. 了解更多
  16. Roquinimex

    Catalog No. A21125
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    Roquinimex (Linomide; PNU212616; ABR212616) is a quinoline derivative immunostimulant which increases NK cell activity and macrophage cytotoxicity; inhibits angiogenesis and reduces the secretion of TNF alpha. 了解更多
  17. L-655708

    Catalog No. A21181
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    GABAA receptor inverse agonist
    L-655708 is a potent α5 subunit-selective GABAA receptor inverse agonist (Ki = 0.45 nM). 了解更多
  18. Zonampanel

    Catalog No. A21199
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    glutamate receptor subtype antagonist
    Zonampanel (YM 872) is a selective antagonist of the glutamate receptor subtype, α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor. 了解更多
  19. Acumapimod

    Catalog No. A21325
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    p38 MAP kinase inhibitor
    Acumapimod (BCT197) is an orally active p38 MAP kinase inhibitor, with an IC50 of less than 1 μM for p38α.385.42 了解更多
  20. Amuvatinib hydrochloride

    Catalog No. A21503
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    multi-targeted tyrosine kinase inhibitor
    Amuvatinib hydrochloride (MP470 hydrochloride) is an orally bioavailable multi-targeted tyrosine kinase inhibitor with potent activity against mutant c-Kit, PDGFRα, Flt3, c-Met and c-Ret. 了解更多
  21. GDC-0927 Racemate

    Catalog No. A21507
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    estrogen receptor degrader
    GDC-0927 Racemate (SRN-927 Racemate) is a degrader of estrogen receptor, potently inhibits ER-α activity, with an IC50 of 0.2 nM, and is used in the research of ER-related diseases. 了解更多
  22. Succinyl phosphonate trisodium salt

    Catalog No. A21508
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    KGDHC inhibitor
    Succinyl phosphonate trisodium salt is an α-ketoglutarate dehydrogenase (KGDHC) inhibitor, effective inhibits (KGDHC) in muscle, bacterial, brain, and cultured human fibroblasts. 了解更多
  23. ENMD-2076 Tartrate

    Catalog No. A21583
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    multi-targeted kinase inhibitor
    ENMD-2076 Tartrate is a multi-targeted kinase inhibitor with IC50s of 1.86, 14, 58.2, 15.9, 92.7, 70.8, 56.4 nM for Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα, respectively. 了解更多
  24. MKC9989

    Catalog No. A21602
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    Hydroxy aryl aldehydes (HAA) inhibitor
    MKC9989 is a Hydroxy aryl aldehydes (HAA) inhibitor and also inhibits IRE1α with an IC50 of 0.23 to 44 μM. 了解更多
  25. Gaboxadol hydrochloride

    Catalog No. A21730
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    GABAA receptors agonist
    Gaboxadol hydrochloride (Lu 02-030 hydrochloride) is a selective agonist at GABAA receptors that contain α4-δ subunits, and has anxiolytic and sedative effects. 了解更多
  26. SKF-86002

    Catalog No. A21893
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    p38 MAP kinase inhibitor
    SKF-86002 is a potent inhibitor of p38 MAP kinase wit IC50 of 0.5-1 uM; inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50 = 1 μM). 了解更多
  27. PF-AKT400

    Catalog No. A21991
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    Akt inhibitor
    PF-AKT400 is a broadly selective, potent, ATP-competitive Akt inhibitor, displays 900-fold greater selectivity for PKBα (IC50=0.5 nM) than PKA (IC50=450 nM). 了解更多
  28. Ralfinamide mesylate

    Catalog No. A22002
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    Na+ channel blocker
    Ralfinamide mesylate (FCE-26742A mesylate) is an orally available Na+ channel blocker derived from α-aminoamide, with function of suppressing pain. 了解更多
  29. Ro 31-8220

    Catalog No. A21765
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    PKC inhibitor
    Ro 31-8220 is a potent PKC inhibitor, with IC50s of 5, 24, 14, 27, 24 and 23 nM for PKCα, PKCβI, PKCβII, PKCγ, PKCε and rat brain PKC, respectively. 了解更多
  30. ISA-2011B

    Catalog No. A20960
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    PIP5K?? inhibitor
    ISA-2011B is a PIP5Kα inhibitor with promising anticancer effects . 了解更多
  31. AFP464

    Catalog No. A20978
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    HIF-1?? inhibitor
    AFP464, is an active HIF-1α inhibitor with an IC50 of 0.25 μM, also is a potent aryl hydrocarbon receptor (AhR) activator. 了解更多
  32. TAS-116

    Catalog No. A20987
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    HSP90??/HSP90?? inhibitor
    TAS-116 is an oral bioavailable, ATP-competitive, highly specific HSP90α/HSP90β inhibitor (Kis of 34.7 nM and 21.3 nM, respectively) without inhibiting other HSP90 family proteins such as GRP94. TAS-116 demonstrates less ocular toxicity. 了解更多
  33. 2-Hydroxybutyric acid

    Catalog No. A19139
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    2-Hydroxybutyric acid (α-Hydroxybutyric acid ) is converted from 2-Aminobutyric acid, with 2-oxobutyric acid as an intermediate metabolite. 了解更多
  34. Quilseconazole

    Catalog No. A19305
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    fungal Cyp51 inhibitor
    Quilseconazole (VT-1129) is a potent, orally active fungal Cyp51 (lanosterol 14-α-demethylase) inhibitor, binds tightly to cryptococcal CYP51, but weakly inhibits humans CYP450 enzymes. 了解更多
  35. TyK2-IN-2

    Catalog No. A19361
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    TYK2 inhibitor
    TyK2-IN-2 (Compoud 18) is a potent and selective TYK2 inhibitor with IC50s of 7 nM, 0.1 μM and 0.05 μM for TYK2 JH2, IL-23 and IFNα, respectively. 了解更多
  36. BT18

    Catalog No. A19378
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    BT18 is a molecule mimic with function similar to glial cell line-derived neurotrophic factor (GDNF). BT18 shows an effect on GDNF family receptor GFRα1 and RET receptor tyrosine kinase RetA function. 了解更多
  37. Toyocamycin

    Catalog No. A19458
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    XBP1 inhibitor
    Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage, with an IC50 of 80 nM. 了解更多
  38. 2,2,5,7,8-Pentamethyl-6-Chromanol

    Catalog No. A19565
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    2,2,5,7,8-Pentamethyl-6-Chromanol (PMC) is the anti-oxidant moiety of vitamin E (α-tocopherol). 2,2,5,7,8-Pentamethyl-6-Chromanol has potent androgen receptor (AR) signaling modulation and anti-cancer activity against prostate cancer cell lines. 了解更多
  39. PI3K/mTOR Inhibitor-2

    Catalog No. A19621
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    dual pan-PI3K/mTOR inhibitor
    PI3K/mTOR Inhibitor-2 is a potent dual pan-PI3K/mTOR inhibitor with IC50s of 3.4/34/16/1 nM for PI3Kα/PI3Kβ/PI3Kδ/PI3Kγ and 4.7 nM for mTOR. Antitumor activity. 了解更多
  40. Melinamide

    Catalog No. A19631
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    cholesterol absorption inhibitor
    Melinamide, an amide derivative of an unsaturated long-chain fatty acid, is an inhibitor of cholesterol absorption with an IC50 of 20.9 μM. 了解更多
  41. N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea

    Catalog No. A19727
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    N-[(1R)-4-[(Aminoiminomethyl)amino]-1-[[[(1R)-1-(4-hydroxyphenyl)ethyl]amino]carbonyl]butyl]-α-phenylbenzeneacetamide is an anticonvulsant agent with potential for the treatment of generalized tonic-clonic and partial seizures. 了解更多
  42. CMPD101

    Catalog No. A19795
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    GRK2/GRK3 inhibitor
    CMPD101, is a novel membrane-permeable, small-molecule inhibitor of both GRK2 and GRK3 with IC50s of 18 nM and 5.4 nM. CMPD101 also inhibits ROCK-2 and PKCα (IC50s=1.4 μM and 8.1 μM, respectively). 了解更多
  43. Deriglidole

    Catalog No. A19898
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    peripheral adrenoceptor antagonist
    Deriglidole is a peripheral adrenoceptor antagonist with a high affinity for α2-adrenoceptors. 了解更多
  44. TES-991

    Catalog No. A19902
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    ACMSD inhibitor
    TES-991 is a potent and selective human α?Amino-β-carboxymuconate-ε-semialdehyde Decarboxylase (ACMSD) inhibitor, with an IC50 of 3 nM. 了解更多
  45. TR antagonist 1

    Catalog No. A19919
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    TR antagonist
    TR antagonist 1 is a high-affinity thyroid hormone receptor (TR) antagonist with IC50s of 36 and 22 nM for TRα and TRβ, respectively. 了解更多
  46. SNAP 94847

    Catalog No. A19925
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    MCHR1 antagonist
    SNAP 94847 is a novel, high affinity selective melanin-concentrating hormonereceptor1 (MCHR1) antagonist with (Ki= 2.2 nM, Kd=530 pM), it displays >80-fold and >500-fold selectivity over MCHα1A and MCHD2 receptors respectively. 了解更多
  47. GC 14

    Catalog No. A19928
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    thyroid hormone receptor antagonist
    GC 14 is a selective thyroid hormone receptor antagonist, with IC50 values of 35 nM and 200 nM for hTRβ and hTRα, respectively. 了解更多
  48. UCB9608

    Catalog No. A19941
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    PI4KIIIβ inhibitor
    UCB9608 is a potent, selective and orally active PI4KIIIβ inhibitor, with an IC50 of 11 nM, selective over PI3KC2 α, β, and γ lipid kinases. 了解更多
  49. H3B-5942

    Catalog No. A19960
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    estrogen receptor covalent antagonist
    H3B-5942 is a selective, irreversible and orally active estrogen receptor covalent antagonist, inactivates both wild-type and mutant ERα by targeting Cys530, with Kis of 1 nM and 0.41 nM, respectively. 了解更多
  50. A 1070722

    Catalog No. A19973
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    GSK-3 inhibitor
    A 1070722 is a potent and selective glycogen synthase kinase 3 (GSK-3) inhibitor, with a Ki of 0.6 nM for both GSK-3α and GSK-3β. 了解更多

产品 301 到 350 共 642个

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