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产品 451 到 500 共 2782个

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  1. Thalidomide-O-amido-C8-NH2

    Catalog No. A20174
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    Thalidomide-O-amido-C8-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. 了解更多
  2. Pyr3

    Catalog No. A20173
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    TRPC3 inhibitor
    Pyr3 is a selective inhibitor of transient receptor potential canonical channel 3 (TRPC3), with an IC50 of 700 nM for TRPC3-mediated Ca2+ influx. 了解更多
  3. MAT2A inhibitor 2

    Catalog No. A20171
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    MAT2A inhibitor
    MAT2A inhibitor 2 is a methionine adenosyltransferase 2A (MAT2A) inhibitor. 了解更多
  4. DC1

    Catalog No. A20170
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    DC1, an analogue of the minor groove-binding DNA alkylator CC-1065, is an antibody conjugate of cytotoxic DNA alkylators for the targeted treatment of cancer. 了解更多
  5. Polymyxin B nonapeptide

    Catalog No. A20168
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    Polymyxin B nonapeptide is a cyclic peptide obtained from Polymyxin B by proteolytic removal of its terminal amino acyl residue. Polymyxin B nonapeptide is less toxic, lacks bactericidal activity, and retains its ability to render gram-negative bacteria susceptible to several antibiotics by permeabilizing their outer membranes. 了解更多
  6. DPPC

    Catalog No. A20167
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    DPPC is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers. 了解更多
  7. Thalidomide-O-amido-PEG3-C2-NH2

    Catalog No. A20161
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    E3 ligase ligand-linker conjugate
    Thalidomide-O-amido-PEG3-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology. 了解更多
  8. GGsTop

    Catalog No. A20160
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    GGT inhibitor
    GGsTop (Nahlsgen) is a potent, non-toxic, highly selective and irreversible γ?glutamyl transpeptidase (GGT) inhibitor, with a Ki of 170 μM for Human GGT. 了解更多
  9. Jaspamycin

    Catalog No. A20153
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    PKA activator
    Jaspamycin (7-CN-7-C-Ino) is a potent activator of PKA, binding to the R site (PKAR), with an EC50 of 6.5 nM and Kd of 8 nM in Trypanosoma brucei. Jaspamycin (7-CN-7-C-Ino) does not bind with purified human PKARIα. Anti-parasite activity. 了解更多
  10. T-3764518

    Catalog No. A20150
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    SCD inhibitor
    T-3764518 is a novel and potent stearoyl coenzyme A desaturase (SCD) inhibitor with an IC50 of 4.7 nM. 了解更多
  11. DIQ3

    Catalog No. A20141
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    DIQ3 is a potent anti-cancer agent, nontoxic to normal human cell lines. 了解更多
  12. Thalidomide-O-amido-PEG3-C2-NH2 (TFA)

    Catalog No. A20133
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    E3 ligase ligand-linker conjugate
    Thalidomide-O-amido-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology. 了解更多
  13. Thalidomide-O-amido-C4-NH2 (TFA)

    Catalog No. A20120
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    E3 ligase ligand-linker conjugate
    Thalidomide-O-amido-C4-NH2 TFA (Cereblon Ligand-Linker Conjugates 6 TFA) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. 了解更多
  14. DAAO inhibitor-1

    Catalog No. A20117
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    DAAO inhibitor
    DAAO inhibitor-1 is a potent D-amino acid oxidase (DAAO) inhibitor with an IC50 of 0.12 μM. 了解更多
  15. Losmiprofen

    Catalog No. A20115
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    antiinflammatory agent
    Losmiprofen is a nonsteroidal antiinflammatory agent. 了解更多
  16. KB SRC 4

    Catalog No. A20111
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    c-Src inhibitor
    KB SRC 4 is a potent, and highly selective c-Src inhibitor, with a Ki of 44 nM and a Kd of 86 nM, and shows no inhibition on c-Abl up to 125 μM; KB SRC 4 has antitumor activity. 了解更多
  17. Thalidomide-O-amido-C8-NH2 (TFA)

    Catalog No. A20108
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    E3 ligase ligand-linker conjugate
    Thalidomide-O-amido-C8-NH2 TFA (Cereblon Ligand -Linker Conjugates 2 TFA) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. 了解更多
  18. Furprofen

    Catalog No. A20107
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    Furprofen is an non-steroidal anti-inflammatory drug (NSAID) with analgesic properties. Furprofen acts via the inhibition of prostaglandin (PGE) synthesis. Furprofen can be treated orally for the relief of pain. 了解更多
  19. Taurochenodeoxycholate-3-sulfate

    Catalog No. A20105
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    Taurochenodeoxycholate-3-sulfate is a bile salt found in urine. 了解更多
  20. Thalidomide-O-amido-C4-N3

    Catalog No. A20097
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    E3 ligase ligand-linker conjugate
    Thalidomide-O-amido-C4-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. 了解更多
  21. EIPA

    Catalog No. A20092
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    TRPP3 channel inhibitor
    EIPA (L593754; MH 12-43) is a TRPP3 channel inhibitor with an IC50 of 10.5 μM. EIPA (L593754; MH 12-43) also inhibits Na+/H+-exchanger (NHE) and macropinocytosis. 了解更多
  22. SB-772077B dihydrochloride

    Catalog No. A20090
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    ROCK inhibitor
    SB-772077B dihydrochloride is an aminofurazan-based Rho kinase (ROCK) inhibitor with IC50s of 5.6 nM and 6 nM toward ROCK1 and ROCK2, respevtively. 了解更多
  23. Pomalidomide-PEG4-C2-NH2

    Catalog No. A20076
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    Pomalidomide-PEG4-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology. 了解更多
  24. S 3304

    Catalog No. A20074
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    MMP inhibitor
    S 3304 is a novel matrix metalloproteinases (MMP) inhibitor specific for MMP-2 and MMP-9. 了解更多
  25. ML-18

    Catalog No. A20057
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    BRS-3 antagonist
    ML-18 is a non-peptide bombesin receptor subtype-3 (BRS-3) antagonist with an IC50 of 4.8 μM. 了解更多
  26. AZD-8529

    Catalog No. A20045
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    mGluR2 modulator
    AZD-8529 is a potent, highly selective and orally bioavailable positive allosteric modulator of mGluR2, with an EC50 of 285 nM, and shows no positive allosteric modulator responses at 20-25 M on the mGluR1, 3, 4, 5, 6, 7, and 8 subtypes. 了解更多
  27. AP5

    Catalog No. A20042
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    AP5 exhibits potent and selective agonism for the GPR40 receptor with positive allosteric modulation of endogenous ligands (AgoPAM). AP5 demonstrates a rat hIP1 EC50 of 0.49±0.28 nM against the GPR40 receptor. 了解更多
  28. BOS-172722

    Catalog No. A20031
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    MPS1 checkpoint
    BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint with an IC50 of 2 nM. 了解更多
  29. mTOR inhibitor-1

    Catalog No. A20029
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    mTOR inhibitor
    mTOR inhibitor-1 is a novel mTOR pathway inhibitor which can suppress cells proliferation and inducing autophagy. 了解更多
  30. Aspartyl-alanyl-diketopiperazine

    Catalog No. A20027
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    Aspartyl-alanyl-diketopiperazine (DA-DKP) is an immunomodulatory molecule generated by cleavage and cyclization from the N-terminus of human albumin and can modulate the inflammatory immune response through a molecular pathway implicated in T- lymphocyte anergy. 了解更多
  31. ODM-204

    Catalog No. A20025
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    androgen receptor/CYP17A1 dual inhibitor
    ODM-204 is novel nonsteroidal dual inhibitor of both androgen receptor and CYP17A1 enzyme, with IC50s of 80?nM and 22 nM, respectively. 了解更多
  32. Arachidonic acid

    Catalog No. A20014
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    Arachidonic acid is an essential fatty acid and a major constituent of biomembranes. 了解更多
  33. N6-(2-Phenylethyl)adenosine

    Catalog No. A20011
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    A1 adenosine receptor agonist
    N6-(2-Phenylethyl)adenosine is a selective A1 adenosine receptor agonist. 了解更多
  34. UVI 3003

    Catalog No. A20010
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    RXR antagonist
    UVI 3003 is a highly selective antagonist of retinoid X receptor (RXR), and inhibits xenopus and human RXRα in Cos7 cells, with IC50s of 0.22 and 0.24 μM, respectively. 了解更多
  35. LMP7-IN-1

    Catalog No. A19995
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    LMP7 inhibitor
    LMP7-IN-1 is an inhibitor of immunoproteasome (LMP7), may used in the research of inflammatory and autoimmune diseases, neurodegenerative diseases, proliferative diseases and cancer. 了解更多
  36. WAY-213613

    Catalog No. A19992
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    GLT-1/EAAT2 reuptake inhibitor
    WAY-213613 is a potent, selective nonsubstrate reuptake inhibitor of GLT-1/EAAT2 with IC50 of 85 nM EAAT2. 了解更多
  37. MGAT2-IN-1

    Catalog No. A19983
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    MGAT2 inhibitor
    MGAT2-IN-1 is an orally active inhibitor of monoacylglycerol acyltransferase (MGAT2) with IC50 of 7.8 and 2.4 nM for human and mouse MGAT2, respectively. 了解更多
  38. NFPS

    Catalog No. A19982
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    GlyT1 inhibitor
    NFPS is a selective, non-competitive glycine transporter-1 (GlyT1) inhibitor with IC50s of 2.8 nM and 9.8 nM for hGlyT1 and rGlyT1, respectively. 了解更多
  39. Reproxalap

    Catalog No. A19978
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    RASP sequestering agent
    Reproxalap (ADX-102) is a reactive aldehyde species (RASP) sequestering agent for the treatment of dry eye. Reproxalap (ADX-102) covalently binds aldehydes including malondialdehyde and 4-hydroxynonenal. 了解更多
  40. Diethylamino hydroxybenzoyl hexyl benzoate

    Catalog No. A19968
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    photostable UV-A absorber
    Diethylamino hydroxybenzoyl hexyl benzoate is a photostable UV-A absorber. 了解更多
  41. 3,4'-Dihydroxyflavone

    Catalog No. A19966
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    3,4'-Dihydroxyflavone (3,4'-DHF) is an oral active flavonoid with antiviral activity against Influenza A virus. 了解更多
  42. N-Nonyldeoxynojirimycin

    Catalog No. A19963
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    alpha-glucosidase/alpha-1,6-glucosidase inhibitor
    N-Nonyldeoxynojirimycin (NN-DNJ) is a potent inhibitor of alpha-glucosidase and alpha-1,6-glucosidase (IC50s, 0.42, 8.4 μM, respectively), inhibits glycogen breakdown. 了解更多
  43. PD-118057

    Catalog No. A19962
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    hERG channel activator
    PD-118057 is a human ether-a-go-go-related gene (hERG) channel activator that does not cause hERG blockade. 了解更多
  44. Prolylleucine

    Catalog No. A19961
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    Prolylleucine is a dipeptide containing branched-chain amino acids. 了解更多
  45. D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt

    Catalog No. A19958
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    D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt is the hexapotassium salt of D-myo-Inositol 1,4,5-trisphosphate (1,4,5-IP3), which is a second messenger that stimulates the discharge of calcium from the endoplasmic reticulum. 了解更多
  46. BRD4 degrader AT1

    Catalog No. A19956
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    Brd4 degrader
    BRD4 degrader AT1 is a highly selective Brd4 degrader based on PROTAC technology, with a Kd of 44 nM for Brd4BD2 in cells. 了解更多
  47. 4'-Methoxyflavonol

    Catalog No. A19955
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    4'-Methoxyflavonol is a synthesized flavone/flavonol with 1, 2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) bilayers. 了解更多
  48. S-methyl-KE-298

    Catalog No. A19954
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    S-methyl-KE-298 is an active metabolite of KE-298. KE-298 inhibits matrix metalloproteinase (MMP-1) production from rheumatoid arthritis (RA) synovial cells. 了解更多
  49. ML 145

    Catalog No. A19953
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    GPR35/CXCR8 antagonist
    ML 145 is a selective GPR35/CXCR8 antagonist with an IC50/EC50 of 20.1 nM, but not for the related GPR55 orphan receptor. GPR35 is expressed by various cells of the immune system and it may has potential as a therapeutic target in inflammatory disease. 了解更多
  50. UDP-GlcNAc Disodium Salt

    Catalog No. A19951
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    OGT donor substrate
    UDP-GlcNAc Disodium Salt (UDP-α-D-N-Acetylglucosamine Disodium Salt) is a donor substrate of O-GlcNAc transferase (OGT). 了解更多

产品 451 到 500 共 2782个

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  2. 9
  3. 10
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