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Zuranolone
Catalog No. A19805 GABAA receptor agonistZuranolone is a potent GABAA receptor agonist with EC50s of 296 and 163 nM for α1β2γ2 and α4β3δ GABAA receptors, respectively. 了解更多 -
1,2,3,6-Tetragalloylglucose
Catalog No. A19802 UGT1A1 inhibitor1,2,3,6-Tetragalloylglucose is a potent UDP glucuronosyltransferase 1 family, polypeptide A1 (UGT1A1) inhibitor, with a Ki of 1.68 μM. 了解更多 -
Duocarmycin MB
Catalog No. A19799 ADCs toxinDuocarmycin MB is an antibody drug conjugates (ADCs) toxin. Duocarmycin is a DNA alkylating agent that binds in the minor groove. Duocarmycin MB can be used against multi-drug resistant cell lines. 了解更多 -
ATRA-hydroxyimino
Catalog No. A19791 ATRA-hydroxyimino (CRABP-II ligand 1), the Retinoic acid (ATRA)-based moiety, binds to cIAP1 ligand (Bestatin) via a linker to form SNIPER to degrade CRABP-II in IMR-32 cells. 了解更多 -
PROTAC CRABP-II Degrader-1
Catalog No. A19782 CRABP-II degraderPROTAC CRABP-II Degrader-1 is a potent cellular retinoic acid binding protein (CRABP-II) degrader based on cIAp1. 了解更多 -
GSK3004774
Catalog No. A19779 CaSR agonistGSK3004774 is a potent, nonabsorbable agonist of CaSR, with an pEC50 of 7.3, 6.6 and 6.5 for human, mouse and rat CaSR, respectively. GSK3004774 shows an EC50 of 50 nM for human CaSR. 了解更多 -
PROTAC CRABP-II Degrader-2
Catalog No. A19773 CRABP-II degraderPROTAC CRABP-II Degrader-2 is a potent cellular retinoic acid binding protein (CRABP-II) degrader based on cIAp1. 了解更多 -
PROTAC CRABP-II Degrader-3
Catalog No. A19764 CRABP-II degraderPROTAC CRABP-II Degrader-3 is a potent cellular retinoic acid binding protein (CRABP-II) degrader based on cIAp1. 了解更多 -
Dabsyl chloride
Catalog No. A19755 amine derivatizing agentDabsyl chloride is an amine derivatizing agent, able to give rise to stable products that can be easily monitored spectrophotometrically at 460 nm; Dabsyl chloride also used for labeling amino acids. 了解更多 -
CDDO-dhTFEA
Catalog No. A19751 CDDO-dhTFEA (RTA dh404) is a synthetic oleanane triterpenoid compound which potently activates Nrf2 and inhibits the pro-inflammatory transcription factor NF-κB. 了解更多 -
INCB-057643
Catalog No. A19737 -
N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea
Catalog No. A19727 N-[(1R)-4-[(Aminoiminomethyl)amino]-1-[[[(1R)-1-(4-hydroxyphenyl)ethyl]amino]carbonyl]butyl]-α-phenylbenzeneacetamide is an anticonvulsant agent with potential for the treatment of generalized tonic-clonic and partial seizures. 了解更多 -
Fluorescein di(β-D-galactopyranoside)
Catalog No. A19707 β-galactosidase fluorogenic substrateFluorescein di(β-D-galactopyranoside) is a fluorogenic substrate for β-galactosidase (λex=485 nm, λem=535 nm). 了解更多 -
Oxyphenisatin acetate
Catalog No. A19700 Oxyphenisatin acetate, the pro-drug of oxyphenisatin, is used to be a laxative. 了解更多 -
5-Methoxyflavone
Catalog No. A19698 DNA polymerase-beta inhibitor5-Methoxyflavone, belonged to Flavonoid family, is a DNA polymerase-beta inhibitor and neuroprotective agent against beta-amyloid toxicity. 了解更多 -
Androstanolone acetate
Catalog No. A19688 androgen ligandAndrostanolone acetate is an androgen ligand, which targets androgen receptor (AR). Androstanolone acetate binds to cIAP1 ligand Bestatin via a linker to form PROTACs. 了解更多 -
Monochlorobimane
Catalog No. A19672 -
5α-Cholestan-3β-ol
Catalog No. A19653 5α-Cholestan-3β-ol is a derivitized steroid compound, which is isolated from the testes of White Carneau pigeons. 了解更多 -
Fradafiban
Catalog No. A19645 platelet glycoprotein IIb/IIIa antagonistFradafiban is a nonpeptide platelet glycoprotein IIb/IIIa antagonist, which binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM. 了解更多 -
Melinamide
Catalog No. A19631 cholesterol absorption inhibitorMelinamide, an amide derivative of an unsaturated long-chain fatty acid, is an inhibitor of cholesterol absorption with an IC50 of 20.9 μM. 了解更多 -
3-Aminopropionitrile fumarate (2:1)
Catalog No. A19629 3-Aminopropionitrile fumarate (2:1) is a lathyrogen which inhibits crosslinking of collagen. 了解更多 -
ABT-702 dihydrochloride
Catalog No. A19624 AK inhibitorABT-702 dihydrochloride is a potent adenosine kinase (AK) inhibitor (IC50=1.7 nM). 了解更多 -
VU0529331
Catalog No. A19614 potassium channel (non-GIRK1/X) activatorVU0529331 is a modestly selective non-GIRK1-containing G protein-gated, inwardly-rectifying, potassium channel (non-GIRK1/X) activator, with EC50s of 5.1 ?M and 5.2 ?M for GIRK2 and GIRK1/2 in HEK293 cells, respectively, also effective on GIRK4 homomeric channel. 了解更多 -
5,6,7-Trimethoxyflavone
Catalog No. A19612 p38-α MAPK inhibitor5,6,7-Trimethoxyflavone is a novel p38-α MAPK inhibitor with an anti-inflammatory effect. 5,6,7-Trimethoxyflavone is isolated from several plants including Zeyhera tuberculosa, Callicarpa japonica, and Kickxia lanigera. 了解更多 -
ReN-1869 hydrochloride
Catalog No. A19610 histamine H1 receptor antagonistReN 1869 hydrochloride is a novel, selective histamine H1 receptor antagonist, which demonstrates affinity to the histamine H1 receptor (guinea pig brain) with Ki of 0.19±0.04 μM and the non-selective ?? site (guinea pig brain) with Ki of 0.45 μM. 了解更多 -
Ketoisophorone
Catalog No. A19608 Ketoisophorone (4-Oxoisophorone) is a key intermediate in the synthesis of carotenoids and flavouring agents. Ketoisophorone is an industrially important cyclic endione. 了解更多 -
PF-06747711
Catalog No. A19605 RORγt inverse agonistPF-06747711 is a potent, selective, and orally active retinoic acid receptor-related orphan C2 (RORC2, also known as RORγt) inverse agonist, with an IC50 of 4.1 nM. Anti-skin inflammatory activity. 了解更多 -
MRE3008F20
Catalog No. A19604 adenosine A3 receptor antagonistMRE3008F20 is a highly potent and selective antagonist of adenosine A3 receptor (AA3R), inhibits agonist-induced cAMP elevation in resting T lymphocytes with an IC50 of 5 nM. 了解更多 -
L-Kynurenine
Catalog No. A19603 aryl hydrocarbon receptor agonistL-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist. 了解更多 -
DS-1040 Tosylate
Catalog No. A19600 TAFIa inhibitorDS-1040 Tosylate is an inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa), used for the treatment of acute ischemic stroke (AIS). 了解更多
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