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GABAA Modulator I
Catalog No. A22646 modulator of the GABAA receptor complexGABAA Modulator I is novel modulator of the GABAA receptor complex, and in particular for combating anxiety and related diseases. 了解更多 -
rac-BHFF
Catalog No. A22659 -
Hexamethonium Bromide
Catalog No. A16572 non-selective ganglionic nicotinic-receptor antagonist (nAChR) antagonistHexamethonium Bromide is a non-selective ganglionic nicotinic-receptor antagonist (nAChR) antagonist, with mixed competitive and noncompetitive activity. 了解更多 -
Toremifene citrate
Catalog No. A10940 estrogen-receptor modulatorToremifene citrate (Z-Toremifene citrate) is a second-generation selective estrogen-receptor modulator (SERM) in development for the prevention of osteoporosis. Toremifene citrate also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.07 ?M and 2.6 ?M, respectively. 了解更多 -
(20S)-Protopanaxatriol
Catalog No. A15649 LXRα inhibitor(20S)-Protopanaxatriol is a metabolite of ginsenoside, works through the glucocorticoid receptor (GR) and oestrogen receptor (ER), and is also a LXRα inhibitor. (20S)-Protopanaxatriol shows a broad spectrum of antitumor effects. 了解更多 -
Eplivanserin
Catalog No. A21967 5-HT2 receptor antagonistEplivanserin is a potent, selective and orally available 5-HT2 receptor antagonist, with an IC50 of 5.8 nM in rat cortical membrane, and a Kd of 1.14 nM. 了解更多 -
WAY-151932
Catalog No. A20821 vasopressin V2-receptor agonistWAY-151932 is a vasopressin V2-receptor agonist with IC50 of 80.3 nM and 778 nM in human-V2 binding and V1a binding assay. 了解更多 -
Phenylbiguanide
Catalog No. A20812 5-HT3 receptor selective agonistPhenylbiguanide is a 5-HT3 receptor selective agonist with an EC50 of 3.0±0.1 μM. 了解更多 -
(-)-Aspartic acid
Catalog No. A20810 -
BMY-25271
Catalog No. A20809 -
Deschloroclozapine
Catalog No. A20801 dual dopamine and serotonin receptor antagonistDeschloroclozapine is a dual dopamine and serotonin receptor antagonist with Kis of 200, 2500, 420, 39, 84, 40 nM for dopamine D1, D2,D4, and serotonin S2A, S2C, S3, respectively. 了解更多 -
trans-ACPD
Catalog No. A20779 metabotropic receptor agonisttrans-ACPD, a metabotropic receptor agonist, produces calcium mobilization and an inward current in cultured cerebellar Purkinje neurons. 了解更多 -
Solabegron
Catalog No. A20778 β3-adrenergic receptor agonistSolabegron (GW 427353) is a selective β3-adrenergic receptor agonist, stimulating cAMP accumulation in Chinese hamster ovary cells expressing the human β3-AR, with an EC50 value of 22 nM. 了解更多 -
Roluperidone
Catalog No. A20770 5-HT2/sigma 2 receptor antagonistRoluperidone, also known as MIN-101, CYR-101, and MT-210, is a 5-HT2A and sigma 2 receptor antagonist potentially for the treatment of schizophrenia. 了解更多 -
SB-616234A
Catalog No. A20764 5-HT1B receptor antagonistSB-616234A is a selective and orally bioavailable 5-HT1B receptor antagonist, with anxiolytic and antidepressant activity. 了解更多 -
GSK2018682
Catalog No. A20752 S1P1/S1P5 receptor agonistGSK2018682 is an agonist for S1P1 and S1P5 receptor with pEC50s of 7.7 and 7.2, respectively, and has no agonist activity towards human S1P2, S1P3, or S1P4. GSK2018682 is used in the research of multiple sclerosis. 了解更多 -
FPR Agonist 43
Catalog No. A20720 dual FPR1/FPR2/ALX agonistFPR Agonist 43 (compound 43) is a dual formyl peptide receptor 1 (FPR1) and formyl peptide receptor 2 (FPR2)/ALX agonist. 了解更多 -
Perzinfotel
Catalog No. A20708 NMDA receptor antagonistPerzinfotel (EAA-090) is a potent, selective, and competitive NMDA receptor antagonist with neuroprotective effects. Perzinfotel (EAA-090) shows high affinity (IC50=30 nM) for the glutamate site. 了解更多 -
CS-003 Free base
Catalog No. A20704 triple tachykinin receptor antagonistCS-003 Free base (CS-003), a triple tachykinin receptor antagonist, shows high affinities for human (Neurokinin) NK1, NK2 and NK3 receptors with Ki values of 2.3 nM, 0.54 nM and 0.74 nM, respectively. 了解更多 -
gamma-DGG
Catalog No. A20685 -
GLP-1R Antagonist 1
Catalog No. A20679 glucagon-like peptide 1 receptor antagonistGLP-1R Antagonist 1 (compound 5d) is an orally active, CNS penetrant and non-competitive antagonist of glucagon-like peptide 1 receptor (GLP-1R), with an IC50 of 650 nM. 了解更多 -
Sultopride
Catalog No. A20663 dopamine D2 receptor antagonistSultopride (LIN-1418) is a selective antagonist of dopamine D2 receptor. 了解更多 -
JNJ-18038683
Catalog No. A20659 5-HT7 receptor antagonistJNJ-18038683 is a 5-Hydroxytryptamine Type 7 (5-HT7) receptor antagonist, with pKis of 8.19, 8.20 for rat and human 5-HT7 in HEK293 cells, respectively. 了解更多 -
GSK1521498
Catalog No. A20649 μ-opioid receptor (MOR) antagonistGSK1521498 is a potent and selective μ-opioid receptor (MOR) antagonist. GSK1521498 is being used for the treatment of disorders of compulsive consumption of food, alcohol, and drugs. 了解更多 -
Adomeglivant
Catalog No. A20647 glucagon receptor antagonistAdomeglivant is a potent and selective glucagon receptor antagonist that is used in clinical trial for type 2 diabetes mellitus. 了解更多 -
Taprenepag isopropyl
Catalog No. A20604 EP2 receptor agonistTaprenepag isopropyl is a highly selective EP2 receptor agonist. 了解更多 -
Quinolinic acid
Catalog No. A20575 NMDA receptor agonistQuinolinic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway and thereby has the potential of mediating N-methyl-D-aspartate neuronal damage and dysfunction. 了解更多 -
Isoguvacine hydrochloride
Catalog No. A20563 -
JNJ16259685
Catalog No. A20545 mGlu1 receptor antagonistJNJ16259685 is a selective antagonist of mGlu1 receptor, and inhibits the synaptic activation of mGlu1 in a concentration-dependent manner with IC50 of 19 nM. 了解更多 -
Naltrindole hydrochloride
Catalog No. A20541 δ opioid receptor antagonistNaltrindole hydrochloride is a highly potent and selective non-peptide δ opioid receptor antagonist with a Ki of 0.02 nM. 了解更多 -
Nicotinamide N-oxide
Catalog No. A20532 CXCR2 receptor antagonistNicotinamide N-oxide, an in vivo nicotinamide metabolite, is a potent, and selective antagonist of the CXCR2 receptor. 了解更多
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